Dbfetch
ID HLA00532; SV 3; standard; DNA; HUM; 11474 BP. XX AC HLA00532; XX SV HLA00532.3 XX DT 01-AUG-1989 (Rel. 1.0.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 3) XX DE HLA-DPB1*15:01:01:01, Human MHC Class II sequence XX KW Human MHC; HLA; Class II; HLA-DPB1; Allele; HLA-DPB1*15:01:01:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-11474 RX PUBMED; 2512583. RA Begovich AB, Bugawan TL, Nepom BS, Klitz W, Nepom GT, Erlich HA; RT "A specific HLA-DP beta allele is associated with pauciarticular juvenile RT rheumatoid arthritis but not adult rheumatoid arthritis."; RL Proceedings of the National Academy of Sciences USA 86:9489-9493(1989). XX RN [2] RP 1-11474 RX PUBMED; 16189666. RA Reinders J, Rozemuller EH, van Gent R, Arts-Hilkes YH, van den Tweel JG, RA Tilanus MG; RT "Extended HLA-DPB1 polymorphism: an RNA approach for HLA-DPB1 typing."; RL Immunogenetics 57:790-794(2005). XX RN [3] RP 1-11474 RX PUBMED; 29879452. RA Klasberg S, Lang K, Gunther M, Schober G, Massalski C, Schmidt AH, Lange V, RA Schofl G; RT "Patterns of non-ARD variation in more than 300 full-length HLA-DPB1 RT alleles."; RL Human Immunology 80:44-52(2019). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AF492636; AF492636.1. DR EMBL; AY804141; AY804141.1. DR EMBL; LT599429; LT599429.1. DR EMBL; LT599430; LT599430.1. DR EMBL; M31779; M31779.1. DR EMBL; M62339; M62339.1. DR EMBL; X72079; X72079.1. XX FH Key Location/Qualifiers FH FT source 1..11474 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="European, Undefined" FT /cell_line="99100835" FT /cell_line="DKMS-LSL-DPB1-1366" FT /cell_line="DKMS-LSL-DPB1-1367" FT /cell_line="PLH" FT CDS join(367..466,5008..5271,9223..9504,10052..10162, FT 10492..10511) FT /codon_start=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*15:01:01:01" FT /product="MHC Class II HLA-DPB1*15:01:01:01 sequence" FT /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYVYQGRQECY FT AFNGTQRFLERYIYNRQEYARFDSDVGEFRAVTELGRPAAEYWNSQKDLLEERRAVPDR FT MCRHNYELVGPMTLQRRVQPKVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYICQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGTFMHRRSKKVQRGSA" FT UTR 1..366 FT exon 367..466 FT /number="1" FT intron 467..5007 FT /number="1" FT exon 5008..5271 FT /number="2" FT intron 5272..9222 FT /number="2" FT exon 9223..9504 FT /number="3" FT intron 9505..10051 FT /number="3" FT exon 10052..10162 FT /number="4" FT intron 10163..10491 FT /number="4" FT exon 10492..10511 FT /number="5" FT UTR 10512..11474 SQ Sequence 11474 BP; 3107 A; 2539 C; 2974 G; 2854 T; 0 other; taatccctgt agatgggcca gcagaatatt tgagatcacc ttcagagcaa agaaaacgca 60 taatctcccc aaacatcatg acttatctga ctggttaaaa tgagtatcac tgtctttcct 120 ccgtcatctt aagtgcatca caggctttat attttcagac ctttcatact aactttctgc 180 ctagtgagca atgactcata caaagctcag tgtccattgg ttcttttctc agactctgtc 240 caatcccagg gtcacagaag actacttggg ttcatggtct ctaatatttc aaacaggagc 300 tccctttagc gagtccttct tttcctgact gcagctcttt tcattttgcc atccttttcc 360 agctccatga tggttctgca ggtttctgcg gccccccgga cagtggctct gacggcgtta 420 ctgatggtgc tgctcacatc tgtggtccag ggcagggcca ctccaggtaa gagccgaact 480 gccattcttg gagggtctgg ctcagggaac aattcctagg ggacgttatc tttaagggat 540 caaattctga gacaggctgc gggggctcct gccctaaggc agtgtcctct cttcccagct 600 agagaaagag gttcatcccc tataggatag cttgctaccc tactggccta ttctctctcc 660 aaggacatgg gtacagtaaa cagagagagg tgcccagtgg tcagtatgct tgtctttggg 720 gaaaatggga ccaagaggtc ctggataacc ttggacagac aaggtttgca cagagagaag 780 ttggcaagtg caggctcctg ggcgtgttca tgtctgcatc cagcctggag gggactcagg 840 cagagagccc taagctggag tgtccaggct ctgaggatca ctgaggattc agtgctcacg 900 aagaatgcct cttattcccc agggtggagc aggagcccac atcccttgga caattaagga 960 gagaagggag ggagggggat aggttttagc ccctgaaggc attctcatta aaggtacttc 1020 tcccagcctc cccagaactt ggttagggta ctagagtggg ttgcgacttg taggaagaat 1080 gagatgaggt tgtgtgggtg catgacaggg attgagtgta ggttatcaga cagccaagga 1140 agcagtaacc aagtgaaaaa tctcttcttc ctgctgcctc cctgtggctg gtgtaatatt 1200 atggcatcta tgatccattg tttttctctc aggatactct caggatattt ctttttatat 1260 atatatatac tttaagttct agggtacatg tgcacaacgt gcaggtttgt tacatatgta 1320 tacatgtgcc atgttggtgt gctgcaccca ttaactcgtc atttacatta ggtatatttc 1380 ctaatgctat ccctcccccc tccccccacc ccacaacagg ccccggtgta tgatgttccc 1440 cttcctgtgt ccatgtgttc tcattgttca gttcccacct atgagtgaga acatgtggtc 1500 tttggttttt tgtccttgca atagtttgct gtgaatgatg gtttccagct tcctccatgt 1560 ccctacaaag gacatgaact catccttttt tatggctgca cagtattcca tggtgtatat 1620 gtgtgcattt tcttaatcca gtctatcact gatggacagt tgggttggtt ccaagtcttt 1680 gctattgtga atagtgccgc aataaacata tgtgtgcatg tgtctttata gcagcatgat 1740 ttataatcct ttgggtatat atccagtaat gggatggctg ggtcaaatgg tatttctagt 1800 tctagatctt tgaggaattg ccacactgtc ttgagatacc atctcacacc agttaaaatg 1860 gcgatcatta aaaagtcagg aaacaacagg tgctggagag gatgtggaga aataggaaca 1920 cttttactct gttggtggga ctgtaaacta gttcaaccat tgtactctca ggacatttct 1980 agtccaaatt tacaccaaca ctctgagagg aaggactgca aagtaggtac cttagttttc 2040 cactgacttc cacttttcct gcttacaccc ttcctcctag acctctccac acccctccta 2100 ggacacacct aaaaggtact gacatcatgt cacctcctca tctttcaggg tagcaaggtt 2160 ggaatctcct gaatacagcc cctcaagccc taaaacctct tatctattac ctcgggttca 2220 tgtccaggaa ggggaggaga acttgaactt atagtcacag aagggtgctg agaactaacc 2280 agcaggacgg ctcagccctg ggaactgcag aggggtgagg ctggggagag aggaggctgg 2340 agcagcactg gtgacactga acagtgtcag gaggaagtga cggatgcagc gcccccatcc 2400 cataggcaga gctgtcatgt gggatgaggg acagtgttgg gagccaccaa ggaaacccag 2460 aggtggggga gcagagagca gaagggggca tgtgatgctg ggcagtgaaa gggaggacgg 2520 gcaaaggctg ggttgaggtt tgtaggggga atgagatgag gcagtggagc catgtgacag 2580 ggactgaggg tagattactg gagctccctg cgtagaatga atgttcaatc aaaacctgct 2640 ggagggagag ctggagccat aggggagtgg gtaaagtggg cagggctgat tccacaattc 2700 cctgcatgct cccccaactc cacacacatc cccaacctca aacagggcac aagaccaaag 2760 ggctgaggag ccaggctata gcttaaagag gctgggggag aaaagcttgg ctgagacaac 2820 ccatagggag ctagaggttt ttaatatatc ctattctgaa taagagacga attcattcag 2880 atcagtggtt tcaaaccgtg ctctgggcaa ctcaattgct aagggttcca caaacaggat 2940 aaagtttctt atatacaaaa aaaatgaagg tttcaaatta caccataaaa cccctcattg 3000 cttatgtcta cttggcaggt aaaattccat ttcaaaagtt aaatgtactt aaaaaattac 3060 ctaagactgg gtaaattaaa aaaattaaat gttgcaaaga aaaaattcaa aattcttatt 3120 cttgaatgaa aaacgttctc ttactggtga ttgaggagga gaaacaaaga ctaacaaatg 3180 aaaatgggag aatccacact cagagtgggg caattgaaca ggcaggggcg gatggatggc 3240 agaggaggag gaatctggac tcaaggagct ggggggctct gggcctggaa tttcagggtc 3300 tggggcccaa ggcaccagga gaagaggcag gtcaggatat ctgagtcaag acctgggatc 3360 ttgccttagc aatgacactg gagactaaag gtggactcca tggtgccctt gagcccagcc 3420 ctaccccatc tccactatcc tctgccacca gctgtgcaac ttctgctagg ggtgaggtta 3480 ataaactgga gaagttaatt tgtggagcat gaaacagatg agcagaacaa tcacagcacc 3540 ttaatttccc cagtgtgccc aagaacagag caggcctgaa gacactcaaa cagaaacaaa 3600 catgtgccgt gtcactgata attctgtgta gacacacacc tgccagacac tgctcatggc 3660 actccctagg aagaacagca tgtgggaaag gctgccaaaa ttgttcatgt aaaaattaca 3720 tcaatgctgt cttcctcggt gctgcctatg cagctggcag ccatctcttc ctccacatca 3780 tggcctccct cagactcctc atgaaggata agatcctcaa aaagaggacc aacaagttca 3840 tgaggcacca atcagactga aatgtcaaaa ttaagcataa ctggcggaaa cccagaggtc 3900 ttaacagtag ggttcgtaga aggtccaagg gccagatctt gatgcccaac attgcttatg 3960 ggagcaacaa caacaacaaa aaacacatgc tgcccagtgg cttccagaag tttctggtcc 4020 acagcctcaa ggagctgaaa gtgctgctga tgtgcaacaa atcttactgt gctgagatcg 4080 ctcacaaaat ttcctccaga actgcaaagt catcatggaa agagtcaccc agccggccat 4140 cagagtcacc aaccccagta ccagggtgca cagctaagaa aatgagtaga aagttcatgt 4200 ccacgttttg tgtgtaaata aaaccataaa aactgccaaa aaaaattaca tcaatgcctc 4260 taaacccaaa ggactctacc cccacaggtc cctggttgtt gtggtgattt tcattgtgta 4320 aaatacttcc cacatctttt gacaccaagt ctttctgcag ccatgtttga aaattaactt 4380 tcaggctaca gagtctttct tataccaaag ttgaagaaag ttttaagaaa tatatttcta 4440 catttcctaa atgcaaaaca acaggagcaa gttgaggaat tctcaagaaa ctggtcgaga 4500 agagagagcg cttagctatg gaaaagagag agaaggaagg gagggcttcc tggaggaggt 4560 ggcatttgaa ccaggactga catcaggatg gaaatgtcag tcagggagtt aagtaggggg 4620 agcagctccg ccctccacgt ccccagctcc tcccgcccct gttttttctc ccagtgaccc 4680 caagtgaaac gtctccgcct cctccagcca ccagcagaag ggactgcctt cccctcagtg 4740 ctcgccactc ctagtgatca ctcagtgccc ctgagcagtg agtctcattc ttttcagtaa 4800 attctctctc tgcgtggtga gaaaacaggc ctggagaggc tctgcgaccc gcttaggacc 4860 acagaactcg atactaggaa aactcctatt ttaaaatcta gccctgagtg ggaagatttg 4920 ggaagaatcg ttaatattga gagagagagg gagaaagagg attagatgag agtggcgcct 4980 ccgctcatgt ccgccccctc cccgcagaga attacgtgta ccagggacgg caggaatgct 5040 acgcgtttaa tgggacacag cgcttcctgg agagatacat ctacaaccgg caggagtacg 5100 cgcgcttcga cagcgacgtg ggagagttcc gggcggtgac ggagctgggg cggcctgctg 5160 cggagtactg gaacagccag aaggacctcc tggaggagag gcgggcagtg ccggacagga 5220 tgtgcagaca caactacgag ctggtcgggc ccatgaccct gcagcgccga ggtgagtgag 5280 ggctttgggc cggcggtccc agggcagccc cgtgggcccg tgcccagggc gcaggagcag 5340 ccgggttggc ctaagggacc ttagtgccaa gcggaaaggg gactttgggt tggggattca 5400 ttgtggggag cccatctgga gcttgtcagg ggagcgagcg cggggacctg gactgggctg 5460 agcatggagt gaggaggacg ggagcagaga gacccccggg acttcatcag gcctggcagc 5520 tgactgcatg tggggtgaga aaaggaggcc acaggacagc gcgcaagggt gtggtgtgga 5580 gatggaggtg gagatggcac agcaggccac acagagaaga aacctgcagg gagatagctg 5640 ggtttgaggt gcttgagggg cagatgggtg gtctgatggg caggtagaca gaagggtctg 5700 cagccgggga ggagactggg atacatgaga ccatccaggg agagaggacc cagggggaag 5760 agcaaaggac tggatcctgg gaactggaca gttgtgattt ggccaagaca gaaaagcctg 5820 tgaaagagac caataaaacc caagtgcagt gtgaggagag gcccgcagag aagagtcttg 5880 gaagctgagg ggaggtgacc tcagcagcac agtggacagc ggtgccagtg acttgggaag 5940 gtcagaaaac agaagatgga aagtgggttt ggaaaccagg gagacctggg gagagcaggt 6000 tggccgcagc ggcaggagct ggaatgggag ggggtgcatg aggctgagtg tggcgcatcc 6060 tcctcggggc tgagatggat tttacttgtc ttgggttccc cacggctggc acagggcagt 6120 gtctgagttc attcatcttt ttccttcagg aagtctgggt gtaaagggat ggagagaggt 6180 gaggtgtgtg cagtaagagg atttctcaag gatgggacag gaaggccttg gagctttggc 6240 ttcctcctgt gaacttgtgg ggtggggagc ctggtgcacc aacctgaggg acctgaggga 6300 gtagtatcag gatgtgggat tgagccctgg accttttttc tagaaagagg aaaaaaatga 6360 agggaggagg aggaggaagc tggggagatc acacctttga ttttcttgtt cctggaaagt 6420 gaaaggaagt tcacctgcta ggagtgagaa ggtggacaca cagggtgggg atgaggtgag 6480 tgacatgagc ttaggaaagt tgctgaggta attggttgag agaggtgttc aaataaaagt 6540 aatgcaattg gcaaaaactg ttactaagac tttgtagagg cacaaatcag tgacatggca 6600 gcatcttctt tcacagtaat caactgccag attgcaggga gccctgatac cagcctaagg 6660 agtgtgagtt tctcctctag gcccacaggt ccccaacctc actcctccga agactctcct 6720 ggagatcatc tgtgatgtgc agatacccag actcactgcc ccgagactca gattccctgg 6780 gtagggaggt cgggggatct ctgcttgtaa tcagctccct agaggttccc atgtagccgg 6840 ataagtattg tcagaacact gaagattttt gaaaaatgaa aaagagaagg ttggagatgt 6900 gtcttcagaa gactactaag ggtgctgggt agaggaggga ccagaggcag ggagatgagg 6960 taggaaactg ctattatttg tcagggaaat tgcaatcaag aaatgagtta gaacagggaa 7020 aacacagagg caggggagag gtggaagggg gaggaaagga gtagtgacaa ttccagggtg 7080 tatgctcacc caaatctaga agtaattgag caaatgtttt ctgggcatta gagaaggcaa 7140 ctagaacaaa caggaatcct tgccttggtg aaatgtattt gaactgggtc agaaatgagg 7200 ccattgggta tcaagcctta actccagcgc cccctggagg tcgctgatgt ggctccaggc 7260 tgacctgctc ctgtcaaaga atattgagca agatgcctct catggaatgt tctgggacct 7320 taaaacagat acccaagtat tccccctgat ttcatggttc ccagaagctc tatggggaag 7380 aaattgtacg taattcacaa ctgagattta gacataagtt gaatagtgta atggacgttg 7440 agttaaccga ggtaatgaag tagtgagaca caggtgcccc tgaaataaac tcacattgag 7500 ggaagaggct gacaatgtgg atcagtctgt aaacaaggca aaaatacaat agggagtaag 7560 ggttgtgtgt cagttcaaga ctgtactttt acctggccca gcgccatgtt ggggtatttg 7620 tgttctccag gaagtagaaa ggaaagaact gagtgattag ggacctagaa gactaatttg 7680 agacattcct cttgatgaac tgttctctag ggtagtcctc tgaaagagct gttctctagt 7740 ggatctccct gaatgaactg ttctctagga gcacttgacc cttttctgtg tttgtttttt 7800 gttttgtgtt tgtgtttgtt tttgagacag gttctcgctc tgtctcccag gctggagtgc 7860 tgtggcgcca tcatgactca ctgcagcctc aacctcctgg gctcaagtga tcctcctgcc 7920 tcagcctccc atgtagctag aactacagat acatgtacca ccatgtctgg ctaatttatt 7980 tttcttttta gagatgggtt ctcactatgt tgcccaggct ggtctcgaaa ccctgggctc 8040 aagtgatcct cacgcctcag cctcccaaag tgctaagatt ataggcatga ccaccatgcc 8100 tggccttttc tgccttccga gaaggaaaaa ggtactggtg gcagagatcc aaaagaaaag 8160 ttgccagtgg cagtgtggaa attgacctga gaacaacaga acaagctggg gcacaaatgc 8220 aaagatgcag agggaggcaa catctggtta tctgtgagac cttcatggga cctgaagaca 8280 catccttttg gaaaaggatg ggatttctac tactcaagca tgtaggggct caggatatta 8340 tgtaaatatg aagattttga gtttttgtaa gtgaggtaaa aaaaatacct aggttattta 8400 cagaataaga catgtcaagc tctcttcatt ttctttgtat tttcatgaaa taaaggtatt 8460 agattaacag gccaccataa tgccattgtc tgtatatctt aatttcaaga tattatttga 8520 gtaatttttg catcctttgt atcaagatag aactttgaaa agacaggtaa tttcacagtt 8580 gattaaatat tctttgccca aattactttt ggttaaaatt tctcctatat gtgctacaga 8640 gtgcaaactc tgtctccctg ccattccgct atatacttac taattattat tttattcaag 8700 atcatgcatg ctctacttga aggtctatct tttcagtgct acccttaccc actagcctaa 8760 tcacattata tctattttca acatctagga atcaattacg tagtgaacat gcctaagaaa 8820 taataatctg ggcagatgca gtggctcagg cctgtaatcc cagcactttg agaggctgag 8880 cgggtggatc acttgaggtc aggagttggt caagtgctcc tagagaacca ggctgaccaa 8940 catggagaaa ccttgtctct actgataata caaaaattag ccaggtgagg tggcaggcac 9000 ctataatccc agctattcgg gaggctgagg aaggagaatt gcttgaaccc ctgaggtgga 9060 ggttgcagtg agccaatatt gcgccactgc attccagact tggcaacaga gcgacactcc 9120 acctcaacaa aaagaaagaa agagcgagat tacgtctcaa aaaaggaagg aaggaaggac 9180 aatctcaaat gctatttcat tattttcctt ccccactcgt agtccagcct aaggtgaacg 9240 tttccccctc caagaagggg cccctgcagc accacaacct gcttgtctgc cacgtgacag 9300 atttctaccc aggcagcatt caagtccgat ggttcctgaa tggacaggag gaaacagctg 9360 gggtcgtgtc caccaacctg atccgtaatg gagactggac cttccagatc ctggtgatgc 9420 tggaaatgac cccccagcag ggagacgtct acatctgcca agtggagcac accagcctgg 9480 acagtcctgt cactgtggag tggagtgagt ctctgatgac cgtctagacc ccacctctga 9540 agagcagggg actctctggc tctggggtcc actcatctta tcttctgcat ctataccctg 9600 gggccatgtc caaaccccat ctttcttcta taccagctcc tgagcatagt ttgaagccag 9660 ggcaatggag acttcctgac cttggcttag gggttcctga agattcatag ttctccccct 9720 tgtcagagaa tctagggaca ctggctgatc tcgaaaccct cacacacagg aactgacctc 9780 acacatagga acagttctct tctttcagca ttttagcctc ttctcaggca ttttgagagg 9840 caacttctag aatcagcatt tgccaccttg ttgaggtcac acccctgttc cggacatgag 9900 ggtggctctt tctgaatttc ctcttagcaa gctttttccc ctgcactgtc ttcatcccga 9960 tattctgcat cacgctccag aatctcagac aggacatgag tagggatgca gctggtggag 10020 gtgacactaa acctgggtct gtccttccca gaggcacagt ctgattctgc ccggagtaag 10080 acattgacgg gagctggggg cttcgtgctg gggctcatca tctgtggagt gggcaccttc 10140 atgcacagga ggagcaagaa aggtgagaaa gcctgcaagg tgagcgggac ttaccttccc 10200 ctggcatatt cacacttact ccatgatgag ggttcagaca gaaaagaaat gtcagaaagc 10260 tctagagacc actgaaatca gatagtcggg gaacaaacat gacctatggc gagaggggga 10320 tcccaggctg ggatcttaat gcagccagat gcatgaggtc ccaggtgctc agactcctgc 10380 ggggcatcca ttgagtggtg gtcaatggaa tttggtggga tggaaatgtt tctctaacta 10440 tctgaggtgg tttcaatggc tgaatacata acctttcctc tttcatttca gttcaacgag 10500 gatctgcata aacaggtaat attcctgctt tgatttcctt ggggggtggg ttacaggagg 10560 atatgactct tttctgtgca ttgtaatact gaggctcctc caggaaggga atctcaggca 10620 tgaacccctc tttcaacctc agctctcggg tgagtgggga aaaagcattg cacggctcca 10680 ttgctgaagg aagcagagat cagttctgtt ctttatcagc ctaagatgca gcctctcacc 10740 ataatttttc tctcctggac ttaaaggaag gaggccagca acctgggata acttgtcctt 10800 tacccccaca gggttcctga cctcaccgaa aagactaatg tgccttagaa caagcatttg 10860 ctgtgttttg ttagcacctg gttccaggac agaccctcag cttcccaaga ggatactgct 10920 gccaagaagt tgctctgaag tcagtttcta tcgttctgct ctttgattca aagcactgtt 10980 tctctcactg ggcctccaac catgttccct tcttcttagc accacaaata atcaaaaccc 11040 aacataagtg tttgttttcc tttaaaaata tgcatcaaat cgtctctcat tacttttctc 11100 tgagggtttt agtaaacagt aggagttaat aaagaagttc attttggttt acacgtagga 11160 aagaagagaa gcatgaaagt ggagatatgt taactattgt ataatgtggc ctgttataca 11220 tgacactctt ctgaattgac tgtatttcag tgagctgccc ccaaatcaag tttagtgccc 11280 tcatccattt atgtctcaga ccgctattct taactattca atggtgagca gactgcaaat 11340 ctgcctgata ggacccgtat tcccacagca ctaattcaac atatatctta ctgagagcat 11400 gttttatcat taccattaag aagttaaatg aacatcagaa tttaaaatca taaatataat 11460 ctaatacact ttaa 11474 //