BLAST @ EBI

BLAST stands for Basic Local Alignment Search Tool. It is used to compare a novel sequence with those contained in nucleotide and protein databases by aligning the novel sequence with previously characterised genes. The emphasis of this tool is to find regions of sequence similarity, which will yield functional and evolutionary clues about the structure and function of this novel sequence. Regions of similarity detected via this type of alignment tool can be either local, where the region of similarity is based in 1 location, or global, where regions of similarity can be detected across otherwise unrelated genetic code.

Below is a list of all the BLAST's available at the EBI. Please note we also provide a 'Programmatic Access to BLAST'.

General BLAST Programs

Tool	Description
WU-BLAST2 Protein	Washington University BLAST2 for protein databases. (BLAST 2.0 with gaps)
WU-BLAST2 Nucleotide	Washington University BLAST2 for nucleotide databases. (BLAST 2.0 with gaps)
NCBI-BLAST2 Protein	NCBI BLAST2 (BLASTALL) program for protein databases.
NCBI-BLAST2 Nucleotide	NCBI BLAST2 (BLASTALL) program for nucleotide databases.

Specialised BLAST Programs

Tool	Description
WU-BLAST2 ASD	ASD BLAST server.
WU-BLAST2 Parasites	Parasite Genomes BLAST server
NCBI-BLAST2 EVEC	European BLAST2 Vector Searches. Check your sequences for vector contamination.
PSI-BLAST   [New Version]	Position specific iterative BLAST (PSI-BLAST) refers to a feature of BLAST 2.0 in which a profile is automatically constructed from the first set of BLAST alignments.
PSI-BLAST   [Old Version]	Position specific iterative BLAST (PSI-BLAST) refers to a feature of BLAST 2.0 in which a profile is automatically constructed from the first set of BLAST alignments.
PHI-BLAST	Pattern Hit Initiated BLAST (PHI-BLAST) treats two occurrence of the same pattern within the query sequence as two independent sequences.

Ensembl Genomes Blast Services New

• Blast EnsemblMetazoa
• Blast Ensembl Bacteria
• Blast EnsemblProtists

Ensembl WU-BLAST2 Programs

BLAST automatically annotated metazoan genomes
using BlastView.