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is a web application that combines Information Retrieval and Extraction from Medline. It retrieves the Medline abstracts that match your search criteria in the same way PubMed does. Then it analyses them to offer a complete overview on associations between UniProt protein/gene names. The associations are ranked in three levels of confidence:

1. Ppi: Pattern matching (natural language processing), being the highest level, this method is precision based.
2. Co3: Tri Co-Occurrence, two protein/gene names are found in conjunction with a verb in a sentence. Overall, the number of times (the number of sentences) the three entities appear together is greater than what can be attributed to chance. This method offers an intermediate confidence level and is a mid step between precision and recall.
3. Co: Co-Occurrence, being the lowest level of confidence, is recall based.

The results are shown in a table that displays all the associations and links them to the sentences that support them as well as to the original abstracts. When appropriate, the involved verbs are also displayed. The table is sorted by relevance so that the associations better supported by the evidence are found higher up.

You can type term queries in the text box provided following the syntax conventions that can be found here. Your terms will be looked up throughout Medline and several abstracts will thus be retrieved and analysed. In the simple interface the higher limit is 500 to make the process quick. You can set a higher limit through the Advanced Search interface. By selecting relevant sentences and highlighting the biomedical terminology Protein Corral enhances your ability to acquire knowledge, relate facts, discover implications and have a good overview economizing the effort in reading.

Indexed fields: PMID, AbstractText, ArticleTitle, AuthorList, MeshHeadingList, DateCreated, DateCompleted, DateRevised, PubDate, Language, MedlineJournalInfo.

Take a minute to visit the sister application EBIMed.