ECCB 2008 Workshop: Annotation, Interpretation and Management of Mutations (AIMM)

Mutations play a key role in the understanding of genetic mechanisms and complex diseases. This workshop will focus on solutions in text mining, data warehousing and machine learning that allow better integration of mutation relevant information into a bioinformatics infrastructure (e.g. workflows, databases, machine learning techniques). Altogether, the meeting participants will discuss methods for the prediction of phenotypic effects induced by mutations, the support to clinical decision processes involving mutations and the means that allow access and management of mutations with annotations from different data resources. Synergistic use of these technologies should facilitate inferences of knowledge from sequence to structure to function and to phenotypes. The workshop brings together members of different disciplines to improve know-how and technology transfer as well as better hypothesis generation for yet un-annotated mutations.

Agenda

The agenda and presentation slides are available here

Organizers

Keynote speakers

Intended audience

This workshop reaches out to the following participants: data architects working on data modeling and knowledge representation, data warehouse curators seeking to address a backlog of un-curated mutations from the literature, designers of mining solutions and services for unstructured text, machine learning specialists developing classifiers for predictive analyses, structural biologists involved in protein engineering and physicians involved in genome scale population studies. The workshop will consist of keynote talks reporting on the management of SNP data and giving better insights on the importance of non-synonymous SNPs on diseases. We invite both long (4000 words / 12 pages) and short papers (2000 words / 6 pages) on the topics listed below.

• novel information extraction, machine learning and other solutions to annotate SNPs
• solutions to manage and combine SNP data
• reports on the integration of bioinformatics solutions into the clinical context

Submissions can be made through the EasyChair submission page. All papers will be published in an online workshop proceedings with CEUR. Long papers may be invited to submit extended versions to a journal special issue.

Important Deadlines

• Paper Submission: July 18th
• Acceptance: August 8th
• Paper Final Version: August 18th
• Workshop: Monday, September 22, 2008
• Venue: ECCB2008 @ Cagliari, Sardinia - Italy