MeSH UP is an online tool for the automatic annotation of biomedical documents with Medical Subject Headings (MeSH) - a controlled vocabulary which has been demonstrated to improve document retrieval in the biomedical domain. A detailed description of this tool, its applications, evaluation and a comparison with other full-scale MeSH classifiers can be found in the following paper:

MeSH UP: Effective MeSH Text Classification for Improved Document Retrieval
Dolf Trieschnigg, Piotr Pezik, Vivian Lee, Franciska de Jong, Wessel Kraaij and Dietrich Rebholz-Schuhmann.
Bioinformatics Advance Access published on April 17, 2009, DOI 10.1093/bioinformatics/btp249.

We provide both manual and programmatic access to MeSH UP. For details, check our help page.