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GO:1990333 mitotic checkpoint complex, CDC20-MAD2 subcomplex

Term Information

ID GO:1990333
Name mitotic checkpoint complex, CDC20-MAD2 subcomplex
Ontology Cellular Component
Definition A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.
PMID:15879521
Comment An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).
GONUTS GO:1990333 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact CDC20-MAD2 complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Protein complexes

Database ID Name
IntAct mad2-cdc20_yeast Mad2-Cdc20 complex

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:1990333:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:1990333. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:1990333 based on the entire annotation set Co-occurrence statistics for GO:1990333 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-03-29 Added RELATION is a GO:0044428 (nuclear part)
2014-03-29 Added RELATION is a GO:0043234 (protein complex)
2014-03-29 Added RELATION part of GO:0033597 (mitotic checkpoint complex)
2014-03-29 Added DEFINITION A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.
2014-03-29 Added SYNONYM CDC20-MAD2 complex
2014-03-29 Added TERM mitotic checkpoint complex, CDC20-MAD2 subcomplex

Term

Timestamp Action Category Detail
2014-03-29 Added TERM mitotic checkpoint complex, CDC20-MAD2 subcomplex

Definition/synonyms

Timestamp Action Category Detail
2014-03-29 Added DEFINITION A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.
2014-03-29 Added SYNONYM CDC20-MAD2 complex

Relationships

Timestamp Action Category Detail
2014-03-29 Added RELATION is a GO:0044428 (nuclear part)
2014-03-29 Added RELATION is a GO:0043234 (protein complex)
2014-03-29 Added RELATION part of GO:0033597 (mitotic checkpoint complex)
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