spacer

GO:0090398 cellular senescence

Term Information

ID GO:0090398
Name cellular senescence
Ontology Biological Process
Definition A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
GONUTS GO:0090398 Wiki Page
Acknowledgements This term was created by the GO Consortium with support from BHF logo

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0090398:
Relationship To GO:0090398 Child Term Child Term Name
Is a GO:0090400 stress-induced premature senescence
Is a GO:0090402 oncogene-induced cell senescence
Regulates GO:2000772 regulation of cellular senescence
Negatively regulates GO:2000773 negative regulation of cellular senescence
Positively regulates GO:2000774 positive regulation of cellular senescence

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0090398. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0090398 based on the entire annotation set Co-occurrence statistics for GO:0090398 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-01-07 Added DEFINITION A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
2011-01-07 Added TERM cellular senescence
2011-01-07 Added RELATION is a GO:0033554 (cellular response to stress)
2011-01-07 Added RELATION is a GO:0007569 (cell aging)

Term

Timestamp Action Category Detail
2011-01-07 Added TERM cellular senescence

Definition/synonyms

Timestamp Action Category Detail
2011-01-07 Added DEFINITION A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.

Relationships

Timestamp Action Category Detail
2011-01-07 Added RELATION is a GO:0033554 (cellular response to stress)
2011-01-07 Added RELATION is a GO:0007569 (cell aging)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
11ms