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GO:0090090 negative regulation of canonical Wnt signaling pathway

Term Information

ID GO:0090090
Name negative regulation of canonical Wnt signaling pathway
Ontology Biological Process
Definition Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GONUTS GO:0090090 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative regulation of canonical Wnt receptor signalling pathway
exact negative regulation of canonical Wnt-activated signaling pathway
exact negative regulation of Wnt receptor signaling pathway through beta-catenin
exact negative regulation of canonical Wnt receptor signaling pathway

GO Discussions

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Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR026837
InterPro IPR029775

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0090090:
Relationship To GO:0090090 Child Term Child Term Name
Is a GO:1901296 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
Is a GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
Is a GO:2000080 negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation
Is a GO:0072336 negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
Is a GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
Is a GO:1902844 positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0090090. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0090090 based on the entire annotation set Co-occurrence statistics for GO:0090090 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-11 Updated TERM negative regulation of canonical Wnt signaling pathway
2013-12-11 Deleted DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2013-12-11 Added DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2013-12-11 Added SYNONYM negative regulation of canonical Wnt-activated signaling pathway
2013-12-11 Added SYNONYM negative regulation of canonical Wnt receptor signaling pathway
2010-11-17 Added SYNONYM negative regulation of canonical Wnt receptor signalling pathway
2010-07-25 Updated TERM negative regulation of canonical Wnt receptor signaling pathway
2010-07-25 Added SYNONYM negative regulation of Wnt receptor signaling pathway through beta-catenin
2010-07-09 Deleted DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes.
2010-07-09 Added DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2009-10-31 Added TERM negative regulation of Wnt receptor signaling pathway through beta-catenin
2009-10-31 Added DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes.
2009-10-31 Added RELATION is a GO:0060828 (regulation of canonical Wnt signaling pathway)
2009-10-31 Added RELATION negatively regulates GO:0060070 (canonical Wnt signaling pathway)
2009-10-31 Added RELATION is a GO:0030178 (negative regulation of Wnt signaling pathway)

Term

Timestamp Action Category Detail
2013-12-11 Updated TERM negative regulation of canonical Wnt signaling pathway
2010-07-25 Updated TERM negative regulation of canonical Wnt receptor signaling pathway
2009-10-31 Added TERM negative regulation of Wnt receptor signaling pathway through beta-catenin

Definition/synonyms

Timestamp Action Category Detail
2013-12-11 Deleted DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2013-12-11 Added DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2013-12-11 Added SYNONYM negative regulation of canonical Wnt-activated signaling pathway
2013-12-11 Added SYNONYM negative regulation of canonical Wnt receptor signaling pathway
2010-11-17 Added SYNONYM negative regulation of canonical Wnt receptor signalling pathway
2010-07-25 Added SYNONYM negative regulation of Wnt receptor signaling pathway through beta-catenin
2010-07-09 Deleted DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes.
2010-07-09 Added DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2009-10-31 Added DEFINITION Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes.

Relationships

Timestamp Action Category Detail
2009-10-31 Added RELATION is a GO:0060828 (regulation of canonical Wnt signaling pathway)
2009-10-31 Added RELATION negatively regulates GO:0060070 (canonical Wnt signaling pathway)
2009-10-31 Added RELATION is a GO:0030178 (negative regulation of Wnt signaling pathway)
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