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GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

This term is obsolete.
This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.

Term Information

ID GO:0072500
Name negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
Ontology Biological Process
Definition OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Comment This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.
GONUTS GO:0072500 Wiki Page

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Consider GO:0000122 Biological Process negative regulation of transcription from RNA polymerase II promoter
Consider GO:0004879 Molecular Function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
Consider GO:0030522 Biological Process intracellular receptor signaling pathway
Consider GO:0038049 Molecular Function ligand-activated RNA polymerase II transcription factor binding transcription factor activity

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0072500:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0072500. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0072500 based on the entire annotation set Co-occurrence statistics for GO:0072500 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-12-09 Updated TERM negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2011-12-09 Deleted DEFINITION Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2011-12-09 Added DEFINITION OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2011-12-09 Deleted RELATION is a GO:0034339 (regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor)
2011-12-09 Added OBSOLETION consider GO:0030522 (intracellular receptor signaling pathway)
2011-12-09 Added OBSOLETION consider GO:0004879 (ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity)
2011-12-09 Added OBSOLETION consider GO:0000122 (negative regulation of transcription from RNA polymerase II promoter)
2011-12-09 Added OBSOLETION consider GO:0038049 (ligand-activated RNA polymerase II transcription factor binding transcription factor activity)
2010-12-19 Added RELATION is a GO:0034339 (regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor)
2010-12-19 Added TERM negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2010-12-19 Added DEFINITION Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Term

Timestamp Action Category Detail
2011-12-09 Updated TERM negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2010-12-19 Added TERM negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

Obsoletions

Timestamp Action Category Detail
2011-12-09 Added OBSOLETION consider GO:0030522 (intracellular receptor signaling pathway)
2011-12-09 Added OBSOLETION consider GO:0004879 (ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity)
2011-12-09 Added OBSOLETION consider GO:0000122 (negative regulation of transcription from RNA polymerase II promoter)
2011-12-09 Added OBSOLETION consider GO:0038049 (ligand-activated RNA polymerase II transcription factor binding transcription factor activity)

Definition/synonyms

Timestamp Action Category Detail
2011-12-09 Deleted DEFINITION Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2011-12-09 Added DEFINITION OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2010-12-19 Added DEFINITION Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Relationships

Timestamp Action Category Detail
2011-12-09 Deleted RELATION is a GO:0034339 (regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor)
2010-12-19 Added RELATION is a GO:0034339 (regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor)
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