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GO:0072376 protein activation cascade

Term Information

ID GO:0072376
Name protein activation cascade
Ontology Biological Process
Definition A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
GONUTS GO:0072376 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact protein activation pathway
exact protein activitory cascade

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0072376:
Relationship To GO:0072376 Child Term Child Term Name
Is a GO:0007598 blood coagulation, extrinsic pathway
Is a GO:0007597 blood coagulation, intrinsic pathway
Is a GO:0006956 complement activation
Is a GO:0002254 kinin cascade
Is a GO:0072377 blood coagulation, common pathway
Is a GO:0072378 blood coagulation, fibrin clot formation
Regulates GO:2000257 regulation of protein activation cascade
Positively regulates GO:2000259 positive regulation of protein activation cascade
Negatively regulates GO:2000258 negative regulation of protein activation cascade

Protein Annotation

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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0072376. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0072376 based on the entire annotation set Co-occurrence statistics for GO:0072376 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-11-28 Added RELATION is a GO:0044710 (single-organism metabolic process)
2013-11-28 Deleted RELATION is a GO:0044699 (single-organism process)
2012-10-09 Added RELATION is a GO:0044699 (single-organism process)
2010-11-25 Added DEFINITION A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
2010-11-25 Deleted DEFINITION A response to a stimulus that consists of a sequential series of modifications to a set of proteinsnwhere the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
2010-11-24 Added TERM protein activation cascade
2010-11-24 Added DEFINITION A response to a stimulus that consists of a sequential series of modifications to a set of proteinsnwhere the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
2010-11-24 Added RELATION is a GO:0050896 (response to stimulus)
2010-11-24 Added RELATION is a GO:0019538 (protein metabolic process)
2010-11-24 Added SYNONYM protein activitory cascade
2010-11-24 Added SYNONYM protein activation pathway

Term

Timestamp Action Category Detail
2010-11-24 Added TERM protein activation cascade

Definition/synonyms

Timestamp Action Category Detail
2010-11-25 Added DEFINITION A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
2010-11-25 Deleted DEFINITION A response to a stimulus that consists of a sequential series of modifications to a set of proteinsnwhere the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
2010-11-24 Added DEFINITION A response to a stimulus that consists of a sequential series of modifications to a set of proteinsnwhere the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
2010-11-24 Added SYNONYM protein activitory cascade
2010-11-24 Added SYNONYM protein activation pathway

Relationships

Timestamp Action Category Detail
2013-11-28 Added RELATION is a GO:0044710 (single-organism metabolic process)
2013-11-28 Deleted RELATION is a GO:0044699 (single-organism process)
2012-10-09 Added RELATION is a GO:0044699 (single-organism process)
2010-11-24 Added RELATION is a GO:0050896 (response to stimulus)
2010-11-24 Added RELATION is a GO:0019538 (protein metabolic process)
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