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GO:0070744 interleukin-27 complex

Term Information

ID GO:0070744
Name interleukin-27 complex
Ontology Cellular Component
Definition A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
PMID:15999093 PMID:19161428
Comment Note that this heterodimeric cytokine utilizes the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-35 uses for its beta chain. Also note that the product of the IL27 gene is the alpha subunit of IL-27. The functional IL-27 protein complex requires both subunits.
GONUTS GO:0070744 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact IL-27 complex
narrow EBI3
narrow p28
narrow IL27

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0070744:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0070744. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0070744 based on the entire annotation set Co-occurrence statistics for GO:0070744 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-06-26 Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 Added SYNONYM p28
2009-06-26 Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 Added RELATION is a GO:0043234 (protein complex)
2009-06-26 Added SYNONYM EBI3
2009-06-26 Added SYNONYM IL-27 complex
2009-06-26 Added SYNONYM IL27
2009-06-26 Added DEFINITION A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
2009-06-26 Added TERM interleukin-27 complex

Term

Timestamp Action Category Detail
2009-06-26 Added TERM interleukin-27 complex

Definition/synonyms

Timestamp Action Category Detail
2009-06-26 Added SYNONYM p28
2009-06-26 Added SYNONYM EBI3
2009-06-26 Added SYNONYM IL-27 complex
2009-06-26 Added SYNONYM IL27
2009-06-26 Added DEFINITION A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.

Relationships

Timestamp Action Category Detail
2009-06-26 Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 Added RELATION is a GO:0043234 (protein complex)
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