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GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway

The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.

Term Information

ID GO:0060397
Name JAK-STAT cascade involved in growth hormone signaling pathway
Ontology Biological Process
Definition The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
Comment

Synonyms

Type Synonym
exact JAK-STAT cascade involved in growth hormone signalling pathway

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Ancestor Table

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GO:0008150 biological_process
GO:0050896 response to stimulus
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0009719 response to endogenous stimulus
GO:0050789 regulation of biological process
GO:0042221 response to chemical stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0010033 response to organic substance
GO:0050794 regulation of cellular process
GO:0070887 cellular response to chemical stimulus
GO:0009725 response to hormone stimulus
GO:0043434 response to peptide hormone stimulus
GO:0007165 signal transduction
GO:0060416 response to growth hormone stimulus
GO:0007242 intracellular signaling cascade
GO:0007166 cell surface receptor linked signal transduction
GO:0007243 protein kinase cascade
GO:0007167 enzyme linked receptor protein signaling pathway
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007259 JAK-STAT cascade
GO:0032870 cellular response to hormone stimulus
GO:0060396 growth hormone receptor signaling pathway
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway

Relationship key

Code Relationship
part of
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regulates
+ve regulates
-ve regulates

Child Terms

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Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
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Taxonomy
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Co-occurring Terms

Co-occurrence statistics

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