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GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway

Term Information

ID GO:0060397
Name JAK-STAT cascade involved in growth hormone signaling pathway
Ontology Biological Process
Definition The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
PMID:11445442
GONUTS GO:0060397 Wiki Page
Acknowledgements This term was created by the GO Consortium with support from BHF logo

Synonyms

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Type Synonym
exact JAK-STAT cascade involved in growth hormone signalling pathway

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Ontology Development Project
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0060397:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0060397. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0060397 based on the entire annotation set Co-occurrence statistics for GO:0060397 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-12-12 Deleted DEFINITION The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
2010-12-12 Added DEFINITION The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
2010-04-21 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-20 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2009-01-12 Added TERM JAK-STAT cascade involved in growth hormone signaling pathway
2009-01-12 Added DEFINITION The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
2009-01-12 Added SYNONYM JAK-STAT cascade involved in growth hormone signalling pathway
2009-01-12 Added RELATION part of GO:0060396 (growth hormone receptor signaling pathway)
2009-01-12 Added RELATION is a GO:0007259 (JAK-STAT cascade)

Term

Timestamp Action Category Detail
2009-01-12 Added TERM JAK-STAT cascade involved in growth hormone signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2010-12-12 Deleted DEFINITION The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
2010-12-12 Added DEFINITION The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
2009-01-12 Added DEFINITION The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
2009-01-12 Added SYNONYM JAK-STAT cascade involved in growth hormone signalling pathway

Relationships

Timestamp Action Category Detail
2010-04-21 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-20 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2009-01-12 Added RELATION part of GO:0060396 (growth hormone receptor signaling pathway)
2009-01-12 Added RELATION is a GO:0007259 (JAK-STAT cascade)
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