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GO:0060337 type I interferon signaling pathway

Term Information

ID GO:0060337
Name type I interferon signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GONUTS GO:0060337 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact type I interferon-mediated signalling pathway
related type I interferon-mediated signaling pathway
exact type I interferon-activated signaling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0001008 GO:0045087 innate immune response never_in_taxon 2, 2157, 4751 Fungi or Bacteria or Archaea
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0060337:
Relationship To GO:0060337 Child Term Child Term Name
Regulates GO:0060338 regulation of type I interferon-mediated signaling pathway
Negatively regulates GO:0060339 negative regulation of type I interferon-mediated signaling pathway
Positively regulates GO:0060340 positive regulation of type I interferon-mediated signaling pathway
Part of GO:0004905 type I interferon receptor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0060337. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0060337 based on the entire annotation set Co-occurrence statistics for GO:0060337 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-11-29 Updated TERM type I interferon signaling pathway
2013-11-29 Added SYNONYM type I interferon-mediated signaling pathway
2013-11-29 Added SYNONYM type I interferon-activated signaling pathway
2013-11-29 Deleted DEFINITION A series of molecular signals initiated by the binding of a type I interferon binding to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2013-11-29 Added DEFINITION A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of a type I interferon binding to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2012-01-18 Deleted DEFINITION A series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2011-01-30 Added RELATION is a GO:0071357 (cellular response to type I interferon)
2009-03-15 Added SYNONYM type I interferon-mediated signalling pathway
2008-10-06 Added DEFINITION A series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2008-10-06 Deleted DEFINITION A series of molecular events generated as a consequence of a type Ininterferon binding to a cell surface receptor. Type I interferons includenthe interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omegangene families.
2008-10-05 Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)
2008-10-05 Added TERM type I interferon-mediated signaling pathway
2008-10-05 Added DEFINITION A series of molecular events generated as a consequence of a type Ininterferon binding to a cell surface receptor. Type I interferons includenthe interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omegangene families.

Term

Timestamp Action Category Detail
2013-11-29 Updated TERM type I interferon signaling pathway
2008-10-05 Added TERM type I interferon-mediated signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2013-11-29 Added SYNONYM type I interferon-mediated signaling pathway
2013-11-29 Added SYNONYM type I interferon-activated signaling pathway
2013-11-29 Deleted DEFINITION A series of molecular signals initiated by the binding of a type I interferon binding to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2013-11-29 Added DEFINITION A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of a type I interferon binding to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2012-01-18 Deleted DEFINITION A series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2009-03-15 Added SYNONYM type I interferon-mediated signalling pathway
2008-10-06 Added DEFINITION A series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2008-10-06 Deleted DEFINITION A series of molecular events generated as a consequence of a type Ininterferon binding to a cell surface receptor. Type I interferons includenthe interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omegangene families.
2008-10-05 Added DEFINITION A series of molecular events generated as a consequence of a type Ininterferon binding to a cell surface receptor. Type I interferons includenthe interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omegangene families.

Relationships

Timestamp Action Category Detail
2011-01-30 Added RELATION is a GO:0071357 (cellular response to type I interferon)
2008-10-05 Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)
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