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GO:0060333 interferon-gamma-mediated signaling pathway

Term Information

ID GO:0060333
Name interferon-gamma-mediated signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
GONUTS GO:0060333 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad type II interferon-mediated signaling pathway
exact interferon-gamma-mediated signalling pathway
exact gamma-interferon-mediated signaling pathway
exact immune interferon signaling pathway
broad type II IFN-mediated signaling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0001008 GO:0045087 innate immune response never_in_taxon 2, 2157, 4751 Fungi or Bacteria or Archaea
More information on taxon constraints in GO is available here

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0060333:
Relationship To GO:0060333 Child Term Child Term Name
Regulates GO:0060334 regulation of interferon-gamma-mediated signaling pathway
Positively regulates GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway
Negatively regulates GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
Part of GO:0004906 interferon-gamma receptor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0060333. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0060333 based on the entire annotation set Co-occurrence statistics for GO:0060333 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-01-08 Added DEFINITION A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
2014-01-08 Deleted DEFINITION A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2014-01-08 Deleted SYNONYM type II interferon-mediated signaling pathway
2014-01-08 Deleted SYNONYM type II IFN-mediated signaling pathway
2014-01-08 Added SYNONYM type II interferon-mediated signaling pathway
2014-01-08 Added SYNONYM type II IFN-mediated signaling pathway
2012-01-14 Deleted DEFINITION A series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
2012-01-14 Added DEFINITION A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2011-01-30 Added RELATION is a GO:0071346 (cellular response to interferon-gamma)
2009-03-15 Added SYNONYM interferon-gamma-mediated signalling pathway
2008-10-05 Added TERM interferon-gamma-mediated signaling pathway
2008-10-05 Added DEFINITION A series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
2008-10-05 Added SYNONYM type II IFN-mediated signaling pathway
2008-10-05 Added SYNONYM type II interferon-mediated signaling pathway
2008-10-05 Added SYNONYM gamma-interferon-mediated signaling pathway
2008-10-05 Added SYNONYM immune interferon signaling pathway
2008-10-05 Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)

Term

Timestamp Action Category Detail
2008-10-05 Added TERM interferon-gamma-mediated signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2014-01-08 Added DEFINITION A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
2014-01-08 Deleted DEFINITION A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2014-01-08 Deleted SYNONYM type II interferon-mediated signaling pathway
2014-01-08 Deleted SYNONYM type II IFN-mediated signaling pathway
2014-01-08 Added SYNONYM type II interferon-mediated signaling pathway
2014-01-08 Added SYNONYM type II IFN-mediated signaling pathway
2012-01-14 Deleted DEFINITION A series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
2012-01-14 Added DEFINITION A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2009-03-15 Added SYNONYM interferon-gamma-mediated signalling pathway
2008-10-05 Added DEFINITION A series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
2008-10-05 Added SYNONYM type II IFN-mediated signaling pathway
2008-10-05 Added SYNONYM type II interferon-mediated signaling pathway
2008-10-05 Added SYNONYM gamma-interferon-mediated signaling pathway
2008-10-05 Added SYNONYM immune interferon signaling pathway

Relationships

Timestamp Action Category Detail
2011-01-30 Added RELATION is a GO:0071346 (cellular response to interferon-gamma)
2008-10-05 Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)
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