spacer

GO:0052621 diguanylate cyclase activity

Term Information

ID GO:0052621
Name diguanylate cyclase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+).
Secondary IDs GO:0043789
GONUTS GO:0052621 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad GTP:GTP guanylyltransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.7.65
KEGG R08057
MetaCyc RXN0-5359
RHEA 24901

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0052621:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0052621. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0052621 based on the entire annotation set Co-occurrence statistics for GO:0052621 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate.
2010-10-11 Added SYNONYM GTP:GTP guanylyltransferase activity
2010-10-11 Deleted SYNONYM GTP:GTP guanylyltransferase activity
2010-10-11 Added XREF RHEA:24901
2010-10-08 Added SECONDARY GO:0043789 (diguanylate cyclase [overall] activity)
2010-10-08 Added XREF KEGG:R08057
2010-10-08 Added SYNONYM GTP:GTP guanylyltransferase activity
2010-09-03 Added RELATION is a GO:0016779 (nucleotidyltransferase activity)
2010-09-03 Added XREF EC:2.7.7.65
2010-09-03 Added XREF MetaCyc:RXN0-5359
2010-09-03 Added DEFINITION Catalysis of the reaction: 2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate.
2010-09-03 Added TERM diguanylate cyclase activity

Term

Timestamp Action Category Detail
2010-09-03 Added TERM diguanylate cyclase activity

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate.
2010-10-11 Added SYNONYM GTP:GTP guanylyltransferase activity
2010-10-11 Deleted SYNONYM GTP:GTP guanylyltransferase activity
2010-10-08 Added SYNONYM GTP:GTP guanylyltransferase activity
2010-09-03 Added DEFINITION Catalysis of the reaction: 2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate.

Relationships

Timestamp Action Category Detail
2010-09-03 Added RELATION is a GO:0016779 (nucleotidyltransferase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:24901
2010-10-08 Added XREF KEGG:R08057
2010-09-03 Added XREF EC:2.7.7.65
2010-09-03 Added XREF MetaCyc:RXN0-5359

Other

Timestamp Action Category Detail
2010-10-08 Added SECONDARY GO:0043789 (diguanylate cyclase [overall] activity)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
12ms