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GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity

Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.

Term Information

ID GO:0051903
Name S-(hydroxymethyl)glutathione dehydrogenase activity
Ontology Molecular Function
Definition Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
Comment

Synonyms

Type Synonym
exact GS-FDH activity
exact NAD- and glutathione-dependent formaldehyde dehydrogenase activity
exact GD-FALDH activity
related FDH activity
narrow ADH3 activity
exact S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity
exact glutathione-dependent formaldehyde dehydrogenase activity
related formic dehydrogenase activity
related class III alcohol dehydrogenase activity
narrow chi-ADH activity
exact NAD-dependent formaldehyde dehydrogenase activity
exact NAD-linked formaldehyde dehydrogenase activity

Cross-references associated with this term:

Database ID
INTERPRO IPR014183
UM-BBD_enzymeID e0709
MetaCyc RXN-2962
EC 1.1.1.284

This term can be used instead of these obsolete terms:

GO:0004327 formaldehyde dehydrogenase (glutathione) activity (consider GO:0051903)

Web service: term information

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Ancestor Chart

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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