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GO:0051864 histone demethylase activity (H3-K36 specific)

Catalysis of the reaction: methyl-lysine + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. The methyl-lysine residue is at position 36 of histone 3.

Term Information

ID GO:0051864
Name histone demethylase activity (H3-K36 specific)
Ontology Molecular Function
Definition Catalysis of the reaction: methyl-lysine + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. The methyl-lysine residue is at position 36 of histone 3.
Comment

Synonyms

Type Synonym
exact histone H3-lysine-36 demethylase activity
exact protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity
exact protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity
exact histone-lysine(H3-K36) demethylase activity
narrow JHDM1A activity
narrow JmjC domain-containing histone demethylase 1A activity
exact histone-lysine (H3-K36) demethylase activity
exact histone-lysine demethylase activity (H3-K36 specific)
exact [histone-H3]-lysine-36 demethylase activity
exact H3-K36-specific demethylase activity

Cross-references associated with this term:

Database ID
EC 1.14.11.27
MetaCyc RXN-8660
MetaCyc RXN-8661

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0032451 demethylase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0032452 histone demethylase activity
GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0051864 histone demethylase activity (H3-K36 specific)

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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