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GO:0016485 protein processing

Term Information

ID GO:0016485
Name protein processing
Ontology Biological Process
Definition Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Secondary IDs GO:0051605
GONUTS GO:0016485 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact protein maturation by peptide bond hydrolysis
exact protein maturation by peptide bond cleavage
related peptidolysis during protein maturation
related protein maturation by proteolysis

Cross-references

Database ID
InterPro IPR000501
InterPro IPR004419
InterPro IPR008710
InterPro IPR009294
InterPro IPR017730
InterPro IPR029734

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0006510 ATP-dependent proteolysis CONSIDER GO:0016485

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016485:
Relationship To GO:0016485 Child Term Child Term Name
Is a GO:0019082 viral protein processing
Is a GO:0006624 vacuolar protein processing
Is a GO:0030908 protein splicing
Is a GO:0016540 protein autoprocessing
Regulates GO:0070613 regulation of protein processing
Is a GO:0034982 mitochondrial protein processing
Is a GO:0090472 dibasic protein processing
Is a GO:0002541 activation of plasma proteins involved in acute inflammatory response
Is a GO:0006465 signal peptide processing
Positively regulates GO:0010954 positive regulation of protein processing
Negatively regulates GO:0010955 negative regulation of protein processing
Is a GO:0016486 peptide hormone processing
Is a GO:0031638 zymogen activation
Is a GO:0035103 sterol regulatory element binding protein cleavage
Is a GO:0035334 Notch receptor processing, ligand-independent
Is a GO:0035551 protein initiator methionine removal involved in protein maturation
Is a GO:0038005 peptide bond cleavage involved in epidermal growth factor receptor ligand maturation
Is a GO:0071586 CAAX-box protein processing
Is a GO:1900756 protein processing in phagocytic vesicle

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016485. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016485 based on the entire annotation set Co-occurrence statistics for GO:0016485 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-03-29 Added RELATION is a GO:0006508 (proteolysis)
2015-03-22 Added RELATION is a GO:0051604 (protein maturation)
2015-03-22 Deleted RELATION is a GO:0019538 (protein metabolic process)
2015-01-08 Added RELATION is a GO:0019538 (protein metabolic process)
2015-01-08 Deleted RELATION is a GO:0051604 (protein maturation)
2011-08-21 Added SYNONYM protein maturation by peptide bond cleavage
2011-08-21 Added SYNONYM protein maturation by peptide bond hydrolysis
2011-08-21 Added SYNONYM peptidolysis during protein maturation
2011-08-21 Deleted DEFINITION Any protein maturation process achieved by the cleavage of peptide bonds.
2011-08-21 Added SYNONYM protein maturation by proteolysis
2011-08-21 Added DEFINITION Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
2011-08-21 Added SECONDARY GO:0051605 (protein maturation by peptide bond cleavage)
2011-08-21 Added RELATION has part GO:0080120 (CAAX-box protein maturation)
2010-02-20 Deleted SYNONYM protein maturation by posttranslational modification
2010-01-31 Deleted DEFINITION The posttranslational modification, which may include cleavage of peptide bonds, of a protein, leading to the attainment of the full functional capacity of the protein. Protein processing particularly affects secretory proteins and proteins targeted for membranes or specific cellular locations.
2010-01-31 Added DEFINITION Any protein maturation process achieved by the cleavage of peptide bonds.
2009-05-03 Added RELATION is a GO:0051604 (protein maturation)
2009-05-03 Deleted RELATION is a GO:0043687 (post-translational protein modification)
2009-05-03 Added SYNONYM protein maturation by posttranslational modification
2009-05-03 Deleted DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2009-05-03 Added DEFINITION The posttranslational modification, which may include cleavage of peptide bonds, of a protein, leading to the attainment of the full functional capacity of the protein. Protein processing particularly affects secretory proteins and proteins targeted for membranes or specific cellular locations.
2008-05-13 Added DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2008-05-12 Deleted DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2008-04-01 Updated RELATION is a GO:0043687 (post-translational protein modification)
2007-06-27 Updated DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2004-03-12 Added DEFINITION The post translational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2002-02-06 Updated TERM protein processing
2001-04-03 Updated TERM protein processing
2001-03-30 Added TERM protein processing

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM protein processing
2001-04-03 Updated TERM protein processing
2001-03-30 Added TERM protein processing

Definition/synonyms

Timestamp Action Category Detail
2011-08-21 Added SYNONYM protein maturation by peptide bond cleavage
2011-08-21 Added SYNONYM protein maturation by peptide bond hydrolysis
2011-08-21 Added SYNONYM peptidolysis during protein maturation
2011-08-21 Deleted DEFINITION Any protein maturation process achieved by the cleavage of peptide bonds.
2011-08-21 Added SYNONYM protein maturation by proteolysis
2011-08-21 Added DEFINITION Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
2010-02-20 Deleted SYNONYM protein maturation by posttranslational modification
2010-01-31 Deleted DEFINITION The posttranslational modification, which may include cleavage of peptide bonds, of a protein, leading to the attainment of the full functional capacity of the protein. Protein processing particularly affects secretory proteins and proteins targeted for membranes or specific cellular locations.
2010-01-31 Added DEFINITION Any protein maturation process achieved by the cleavage of peptide bonds.
2009-05-03 Added SYNONYM protein maturation by posttranslational modification
2009-05-03 Deleted DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2009-05-03 Added DEFINITION The posttranslational modification, which may include cleavage of peptide bonds, of a protein, leading to the attainment of the full functional capacity of the protein. Protein processing particularly affects secretory proteins and proteins targeted for membranes or specific cellular locations.
2008-05-13 Added DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2008-05-12 Deleted DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2007-06-27 Updated DEFINITION The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.
2004-03-12 Added DEFINITION The post translational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.

Relationships

Timestamp Action Category Detail
2015-03-29 Added RELATION is a GO:0006508 (proteolysis)
2015-03-22 Added RELATION is a GO:0051604 (protein maturation)
2015-03-22 Deleted RELATION is a GO:0019538 (protein metabolic process)
2015-01-08 Added RELATION is a GO:0019538 (protein metabolic process)
2015-01-08 Deleted RELATION is a GO:0051604 (protein maturation)
2011-08-21 Added RELATION has part GO:0080120 (CAAX-box protein maturation)
2009-05-03 Added RELATION is a GO:0051604 (protein maturation)
2009-05-03 Deleted RELATION is a GO:0043687 (post-translational protein modification)
2008-04-01 Updated RELATION is a GO:0043687 (post-translational protein modification)

Other

Timestamp Action Category Detail
2011-08-21 Added SECONDARY GO:0051605 (protein maturation by peptide bond cleavage)
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