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GO:0051444 negative regulation of ubiquitin-protein transferase activity

Term Information

ID GO:0051444
Name negative regulation of ubiquitin-protein transferase activity
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.
GONUTS GO:0051444 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow APC inhibition
narrow APC inhibitor
exact downregulation of ubiquitin transferase activity
exact down-regulation of ubiquitin transferase activity
narrow ubiquitin transferase inhibitor
narrow inhibition of ubiquitin transferase activity
exact down regulation of ubiquitin transferase activity
exact negative regulation of ubiquitin transferase activity
narrow anaphase-promoting complex inhibitor
narrow anaphase-promoting complex inhibition
narrow anaphase promoting complex inhibitor
narrow anaphase promoting complex inhibition
narrow SCF complex inhibitor

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0051444:
Relationship To GO:0051444 Child Term Child Term Name
Is a GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
Is a GO:0051442 negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0051444. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0051444 based on the entire annotation set Co-occurrence statistics for GO:0051444 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-05-20 Added SYNONYM downregulation of ubiquitin transferase activity
2014-05-20 Added RELATION is a GO:0051348 (negative regulation of transferase activity)
2014-05-20 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2014-05-20 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.
2014-05-20 Updated TERM negative regulation of ubiquitin-protein transferase activity
2014-05-20 Deleted SYNONYM downregulation of ubiquitin ligase activity
2014-05-20 Deleted SYNONYM inhibition of ubiquitin ligase activity
2014-05-20 Deleted SYNONYM down regulation of ubiquitin ligase activity
2014-05-20 Added SYNONYM negative regulation of ubiquitin transferase activity
2014-05-20 Added SYNONYM down regulation of ubiquitin transferase activity
2014-05-20 Added SYNONYM inhibition of ubiquitin transferase activity
2014-05-20 Added SYNONYM ubiquitin transferase inhibitor
2014-05-20 Added SYNONYM down-regulation of ubiquitin transferase activity
2014-05-20 Deleted SYNONYM ubiquitin ligase inhibitor
2014-05-20 Deleted SYNONYM down-regulation of ubiquitin ligase activity
2014-05-20 Deleted SYNONYM negative regulation of ubiquitin ligase activity
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2010-06-15 Added RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2010-06-09 Updated TERM negative regulation of ubiquitin-protein ligase activity
2010-06-08 Added RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2010-06-08 Updated TERM negative regulation of ubiquitin-protein ligase activity
2010-02-27 Added RELATION is a GO:0031397 (negative regulation of protein ubiquitination)
2009-02-25 Updated TERM negative regulation of ubiquitin-protein ligase activity
2009-02-25 Deleted RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2009-02-22 Added RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2009-02-22 Updated TERM negative regulation of ubiquitin-protein ligase activity
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2008-04-01 Updated RELATION is a GO:0051438 (regulation of ubiquitin-protein transferase activity)
2008-04-01 Updated RELATION is a GO:0051352 (negative regulation of ligase activity)
2007-10-13 Added SYNONYM negative regulation of ubiquitin ligase activity
2007-10-13 Updated TERM negative regulation of ubiquitin-protein ligase activity
2007-08-09 Added SYNONYM APC inhibition
2007-08-09 Added SYNONYM APC inhibitor
2007-08-09 Added SYNONYM SCF complex inhibitor
2007-08-09 Added SYNONYM anaphase promoting complex inhibition
2007-08-09 Added SYNONYM anaphase promoting complex inhibitor
2007-08-09 Added SYNONYM anaphase-promoting complex inhibition
2007-08-09 Added SYNONYM anaphase-promoting complex inhibitor
2007-08-09 Added SYNONYM down regulation of ubiquitin ligase activity
2007-08-09 Added SYNONYM down-regulation of ubiquitin ligase activity
2007-08-09 Added SYNONYM downregulation of ubiquitin ligase activity
2007-08-09 Added SYNONYM inhibition of ubiquitin ligase activity
2007-08-09 Added SYNONYM ubiquitin ligase inhibitor
2007-08-09 Deleted SYNONYM down regulation of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM down-regulation of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM downregulation of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM inhibition of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM APC inhibition
2007-08-09 Deleted SYNONYM APC inhibitor
2007-08-09 Deleted SYNONYM SCF complex inhibitor
2007-08-09 Deleted SYNONYM anaphase promoting complex inhibition
2007-08-09 Deleted SYNONYM anaphase promoting complex inhibitor
2007-08-09 Deleted SYNONYM anaphase-promoting complex inhibition
2007-08-09 Deleted SYNONYM anaphase-promoting complex inhibitor
2007-08-09 Deleted SYNONYM ubiquitin ligase inhibitor
2007-02-23 Added SYNONYM down regulation of ubiquitin ligase activity
2007-02-23 Added SYNONYM down-regulation of ubiquitin ligase activity
2007-02-23 Added SYNONYM downregulation of ubiquitin ligase activity
2007-02-23 Added SYNONYM inhibition of ubiquitin ligase activity
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-07-17 Added SYNONYM anaphase promoting complex inhibition
2005-07-17 Added SYNONYM anaphase promoting complex inhibitor
2005-07-04 Added TERM negative regulation of ubiquitin ligase activity
2005-07-04 Added DEFINITION Any process that stops, prevents or reduces the rate of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-07-04 Added SYNONYM APC inhibition
2005-07-04 Added SYNONYM APC inhibitor
2005-07-04 Added SYNONYM SCF complex inhibitor
2005-07-04 Added SYNONYM anaphase-promoting complex inhibition
2005-07-04 Added SYNONYM anaphase-promoting complex inhibitor
2005-07-04 Added SYNONYM ubiquitin ligase inhibitor

Term

Timestamp Action Category Detail
2014-05-20 Updated TERM negative regulation of ubiquitin-protein transferase activity
2010-06-09 Updated TERM negative regulation of ubiquitin-protein ligase activity
2010-06-08 Updated TERM negative regulation of ubiquitin-protein ligase activity
2009-02-25 Updated TERM negative regulation of ubiquitin-protein ligase activity
2009-02-22 Updated TERM negative regulation of ubiquitin-protein ligase activity
2007-10-13 Updated TERM negative regulation of ubiquitin-protein ligase activity
2005-07-04 Added TERM negative regulation of ubiquitin ligase activity

Definition/synonyms

Timestamp Action Category Detail
2014-05-20 Added SYNONYM downregulation of ubiquitin transferase activity
2014-05-20 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2014-05-20 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.
2014-05-20 Deleted SYNONYM downregulation of ubiquitin ligase activity
2014-05-20 Deleted SYNONYM inhibition of ubiquitin ligase activity
2014-05-20 Deleted SYNONYM down regulation of ubiquitin ligase activity
2014-05-20 Added SYNONYM negative regulation of ubiquitin transferase activity
2014-05-20 Added SYNONYM down regulation of ubiquitin transferase activity
2014-05-20 Added SYNONYM inhibition of ubiquitin transferase activity
2014-05-20 Added SYNONYM ubiquitin transferase inhibitor
2014-05-20 Added SYNONYM down-regulation of ubiquitin transferase activity
2014-05-20 Deleted SYNONYM ubiquitin ligase inhibitor
2014-05-20 Deleted SYNONYM down-regulation of ubiquitin ligase activity
2014-05-20 Deleted SYNONYM negative regulation of ubiquitin ligase activity
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2007-10-13 Added SYNONYM negative regulation of ubiquitin ligase activity
2007-08-09 Added SYNONYM APC inhibition
2007-08-09 Added SYNONYM APC inhibitor
2007-08-09 Added SYNONYM SCF complex inhibitor
2007-08-09 Added SYNONYM anaphase promoting complex inhibition
2007-08-09 Added SYNONYM anaphase promoting complex inhibitor
2007-08-09 Added SYNONYM anaphase-promoting complex inhibition
2007-08-09 Added SYNONYM anaphase-promoting complex inhibitor
2007-08-09 Added SYNONYM down regulation of ubiquitin ligase activity
2007-08-09 Added SYNONYM down-regulation of ubiquitin ligase activity
2007-08-09 Added SYNONYM downregulation of ubiquitin ligase activity
2007-08-09 Added SYNONYM inhibition of ubiquitin ligase activity
2007-08-09 Added SYNONYM ubiquitin ligase inhibitor
2007-08-09 Deleted SYNONYM down regulation of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM down-regulation of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM downregulation of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM inhibition of ubiquitin ligase activity
2007-08-09 Deleted SYNONYM APC inhibition
2007-08-09 Deleted SYNONYM APC inhibitor
2007-08-09 Deleted SYNONYM SCF complex inhibitor
2007-08-09 Deleted SYNONYM anaphase promoting complex inhibition
2007-08-09 Deleted SYNONYM anaphase promoting complex inhibitor
2007-08-09 Deleted SYNONYM anaphase-promoting complex inhibition
2007-08-09 Deleted SYNONYM anaphase-promoting complex inhibitor
2007-08-09 Deleted SYNONYM ubiquitin ligase inhibitor
2007-02-23 Added SYNONYM down regulation of ubiquitin ligase activity
2007-02-23 Added SYNONYM down-regulation of ubiquitin ligase activity
2007-02-23 Added SYNONYM downregulation of ubiquitin ligase activity
2007-02-23 Added SYNONYM inhibition of ubiquitin ligase activity
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-07-17 Added SYNONYM anaphase promoting complex inhibition
2005-07-17 Added SYNONYM anaphase promoting complex inhibitor
2005-07-04 Added DEFINITION Any process that stops, prevents or reduces the rate of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-07-04 Added SYNONYM APC inhibition
2005-07-04 Added SYNONYM APC inhibitor
2005-07-04 Added SYNONYM SCF complex inhibitor
2005-07-04 Added SYNONYM anaphase-promoting complex inhibition
2005-07-04 Added SYNONYM anaphase-promoting complex inhibitor
2005-07-04 Added SYNONYM ubiquitin ligase inhibitor

Relationships

Timestamp Action Category Detail
2014-05-20 Added RELATION is a GO:0051348 (negative regulation of transferase activity)
2010-06-15 Added RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2010-06-08 Added RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2010-02-27 Added RELATION is a GO:0031397 (negative regulation of protein ubiquitination)
2009-02-25 Deleted RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2009-02-22 Added RELATION negatively regulates GO:0004842 (ubiquitin-protein transferase activity)
2008-04-01 Updated RELATION is a GO:0051438 (regulation of ubiquitin-protein transferase activity)
2008-04-01 Updated RELATION is a GO:0051352 (negative regulation of ligase activity)
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