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GO:0051352 negative regulation of ligase activity

Term Information

ID GO:0051352
Name negative regulation of ligase activity
Ontology Biological Process
Definition Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
GONUTS GO:0051352 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact downregulation of ligase activity
exact down-regulation of ligase activity
exact down regulation of ligase activity
exact ligase inhibitor
narrow inhibition of ligase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0051352:
Relationship To GO:0051352 Child Term Child Term Name
Is a GO:0051444 negative regulation of ubiquitin-protein transferase activity
Is a GO:0035228 negative regulation of glutamate-cysteine ligase activity
Is a GO:1903183 negative regulation of SUMO transferase activity
Is a GO:1903631 negative regulation of aminoacyl-tRNA ligase activity
Is a GO:1903634 negative regulation of leucine-tRNA ligase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0051352. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0051352 based on the entire annotation set Co-occurrence statistics for GO:0051352 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-06-15 Added RELATION negatively regulates GO:0016874 (ligase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0016874 (ligase activity)
2010-06-09 Updated TERM negative regulation of ligase activity
2010-06-08 Added RELATION negatively regulates GO:0016874 (ligase activity)
2010-06-08 Updated TERM negative regulation of ligase activity
2009-02-25 Updated TERM negative regulation of ligase activity
2009-02-25 Deleted RELATION negatively regulates GO:0016874 (ligase activity)
2009-02-22 Added RELATION negatively regulates GO:0016874 (ligase activity)
2009-02-22 Updated TERM negative regulation of ligase activity
2008-05-13 Added DEFINITION Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-05-12 Deleted DEFINITION Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-04-01 Updated RELATION is a GO:0051340 (regulation of ligase activity)
2008-04-01 Updated RELATION is a GO:0043086 (negative regulation of catalytic activity)
2007-08-09 Added SYNONYM down regulation of ligase activity
2007-08-09 Added SYNONYM down-regulation of ligase activity
2007-08-09 Added SYNONYM downregulation of ligase activity
2007-08-09 Added SYNONYM inhibition of ligase activity
2007-08-09 Added SYNONYM ligase inhibitor
2007-08-09 Deleted SYNONYM down regulation of ligase activity
2007-08-09 Deleted SYNONYM down-regulation of ligase activity
2007-08-09 Deleted SYNONYM downregulation of ligase activity
2007-08-09 Deleted SYNONYM inhibition of ligase activity
2007-08-09 Deleted SYNONYM ligase inhibitor
2007-02-23 Added SYNONYM down regulation of ligase activity
2007-02-23 Added SYNONYM down-regulation of ligase activity
2007-02-23 Added SYNONYM downregulation of ligase activity
2007-02-23 Added SYNONYM inhibition of ligase activity
2005-02-25 Added DEFINITION Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
2005-02-24 Added SYNONYM ligase inhibitor
2005-02-24 Added TERM negative regulation of ligase activity

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM negative regulation of ligase activity
2010-06-08 Updated TERM negative regulation of ligase activity
2009-02-25 Updated TERM negative regulation of ligase activity
2009-02-22 Updated TERM negative regulation of ligase activity
2005-02-24 Added TERM negative regulation of ligase activity

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-05-12 Deleted DEFINITION Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
2007-08-09 Added SYNONYM down regulation of ligase activity
2007-08-09 Added SYNONYM down-regulation of ligase activity
2007-08-09 Added SYNONYM downregulation of ligase activity
2007-08-09 Added SYNONYM inhibition of ligase activity
2007-08-09 Added SYNONYM ligase inhibitor
2007-08-09 Deleted SYNONYM down regulation of ligase activity
2007-08-09 Deleted SYNONYM down-regulation of ligase activity
2007-08-09 Deleted SYNONYM downregulation of ligase activity
2007-08-09 Deleted SYNONYM inhibition of ligase activity
2007-08-09 Deleted SYNONYM ligase inhibitor
2007-02-23 Added SYNONYM down regulation of ligase activity
2007-02-23 Added SYNONYM down-regulation of ligase activity
2007-02-23 Added SYNONYM downregulation of ligase activity
2007-02-23 Added SYNONYM inhibition of ligase activity
2005-02-25 Added DEFINITION Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
2005-02-24 Added SYNONYM ligase inhibitor

Relationships

Timestamp Action Category Detail
2010-06-15 Added RELATION negatively regulates GO:0016874 (ligase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0016874 (ligase activity)
2010-06-08 Added RELATION negatively regulates GO:0016874 (ligase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0016874 (ligase activity)
2009-02-22 Added RELATION negatively regulates GO:0016874 (ligase activity)
2008-04-01 Updated RELATION is a GO:0051340 (regulation of ligase activity)
2008-04-01 Updated RELATION is a GO:0043086 (negative regulation of catalytic activity)
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