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GO:0051346 negative regulation of hydrolase activity

Term Information

ID GO:0051346
Name negative regulation of hydrolase activity
Ontology Biological Process
Definition Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GONUTS GO:0051346 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact down regulation of hydrolase activity
exact down-regulation of hydrolase activity
exact downregulation of hydrolase activity
exact hydrolase inhibitor
narrow inhibition of hydrolase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0051346:
Relationship To GO:0051346 Child Term Child Term Name
Is a GO:0043105 negative regulation of GTP cyclohydrolase I activity
Is a GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity
Is a GO:0051422 negative regulation of endo-1,4-beta-xylanase activity
Is a GO:0032074 negative regulation of nuclease activity
Is a GO:0010466 negative regulation of peptidase activity
Is a GO:0051097 negative regulation of helicase activity
Is a GO:0032780 negative regulation of ATPase activity
Is a GO:0060192 negative regulation of lipase activity
Is a GO:0034260 negative regulation of GTPase activity
Is a GO:0010923 negative regulation of phosphatase activity
Is a GO:1902545 negative regulation of DNA N-glycosylase activity
Is a GO:1903016 negative regulation of exo-alpha-sialidase activity
Is a GO:1901726 negative regulation of histone deacetylase activity
Is a GO:2000575 negative regulation of microtubule motor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0051346. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0051346 based on the entire annotation set Co-occurrence statistics for GO:0051346 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-06-15 Added RELATION negatively regulates GO:0016787 (hydrolase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0016787 (hydrolase activity)
2010-06-09 Updated TERM negative regulation of hydrolase activity
2010-06-08 Added RELATION negatively regulates GO:0016787 (hydrolase activity)
2010-06-08 Updated TERM negative regulation of hydrolase activity
2009-02-25 Updated TERM negative regulation of hydrolase activity
2009-02-25 Deleted RELATION negatively regulates GO:0016787 (hydrolase activity)
2009-02-22 Added RELATION negatively regulates GO:0016787 (hydrolase activity)
2009-02-22 Updated TERM negative regulation of hydrolase activity
2008-05-13 Added DEFINITION Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
2008-05-12 Deleted DEFINITION Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
2008-04-01 Updated RELATION is a GO:0051336 (regulation of hydrolase activity)
2008-04-01 Updated RELATION is a GO:0043086 (negative regulation of catalytic activity)
2007-08-09 Added SYNONYM down regulation of hydrolase activity
2007-08-09 Added SYNONYM down-regulation of hydrolase activity
2007-08-09 Added SYNONYM downregulation of hydrolase activity
2007-08-09 Added SYNONYM hydrolase inhibitor
2007-08-09 Added SYNONYM inhibition of hydrolase activity
2007-08-09 Deleted SYNONYM down regulation of hydrolase activity
2007-08-09 Deleted SYNONYM down-regulation of hydrolase activity
2007-08-09 Deleted SYNONYM downregulation of hydrolase activity
2007-08-09 Deleted SYNONYM inhibition of hydrolase activity
2007-08-09 Deleted SYNONYM hydrolase inhibitor
2007-02-23 Added SYNONYM down regulation of hydrolase activity
2007-02-23 Added SYNONYM down-regulation of hydrolase activity
2007-02-23 Added SYNONYM downregulation of hydrolase activity
2007-02-23 Added SYNONYM inhibition of hydrolase activity
2005-02-25 Added DEFINITION Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
2005-02-24 Added SYNONYM hydrolase inhibitor
2005-02-24 Added TERM negative regulation of hydrolase activity

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM negative regulation of hydrolase activity
2010-06-08 Updated TERM negative regulation of hydrolase activity
2009-02-25 Updated TERM negative regulation of hydrolase activity
2009-02-22 Updated TERM negative regulation of hydrolase activity
2005-02-24 Added TERM negative regulation of hydrolase activity

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
2008-05-12 Deleted DEFINITION Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
2007-08-09 Added SYNONYM down regulation of hydrolase activity
2007-08-09 Added SYNONYM down-regulation of hydrolase activity
2007-08-09 Added SYNONYM downregulation of hydrolase activity
2007-08-09 Added SYNONYM hydrolase inhibitor
2007-08-09 Added SYNONYM inhibition of hydrolase activity
2007-08-09 Deleted SYNONYM down regulation of hydrolase activity
2007-08-09 Deleted SYNONYM down-regulation of hydrolase activity
2007-08-09 Deleted SYNONYM downregulation of hydrolase activity
2007-08-09 Deleted SYNONYM inhibition of hydrolase activity
2007-08-09 Deleted SYNONYM hydrolase inhibitor
2007-02-23 Added SYNONYM down regulation of hydrolase activity
2007-02-23 Added SYNONYM down-regulation of hydrolase activity
2007-02-23 Added SYNONYM downregulation of hydrolase activity
2007-02-23 Added SYNONYM inhibition of hydrolase activity
2005-02-25 Added DEFINITION Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
2005-02-24 Added SYNONYM hydrolase inhibitor

Relationships

Timestamp Action Category Detail
2010-06-15 Added RELATION negatively regulates GO:0016787 (hydrolase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0016787 (hydrolase activity)
2010-06-08 Added RELATION negatively regulates GO:0016787 (hydrolase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0016787 (hydrolase activity)
2009-02-22 Added RELATION negatively regulates GO:0016787 (hydrolase activity)
2008-04-01 Updated RELATION is a GO:0051336 (regulation of hydrolase activity)
2008-04-01 Updated RELATION is a GO:0043086 (negative regulation of catalytic activity)
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