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GO:0050709 negative regulation of protein secretion

Term Information

ID GO:0050709
Name negative regulation of protein secretion
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
GONUTS GO:0050709 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact downregulation of protein secretion
exact down-regulation of protein secretion
narrow inhibition of protein secretion
exact down regulation of protein secretion

Cross-references

Database ID
InterPro IPR013401
InterPro IPR027048

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0050709:
Relationship To GO:0050709 Child Term Child Term Name
Is a GO:0046676 negative regulation of insulin secretion
Is a GO:0050710 negative regulation of cytokine secretion
Is a GO:0051025 negative regulation of immunoglobulin secretion
Is a GO:0061358 negative regulation of Wnt protein secretion
Is a GO:0070164 negative regulation of adiponectin secretion
Is a GO:0090341 negative regulation of secretion of lysosomal enzymes
Is a GO:1900134 negative regulation of renin secretion into blood stream
Is a GO:1902277 negative regulation of pancreatic amylase secretion
Is a GO:1902721 negative regulation of prolactin secretion
Is a GO:2001285 negative regulation of BMP secretion
Is a GO:1904243 negative regulation of pancreatic trypsinogen secretion
Is a GO:1904465 negative regulation of matrix metallopeptidase secretion

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0050709. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0050709 based on the entire annotation set Co-occurrence statistics for GO:0050709 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-10-10 Added RELATION is a GO:1903531 (negative regulation of secretion by cell)
2014-10-10 Deleted RELATION is a GO:0051048 (negative regulation of secretion)
2014-10-10 Deleted RELATION is a GO:0048523 (negative regulation of cellular process)
2013-02-15 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2013-02-15 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2009-06-16 Added RELATION is a GO:0048523 (negative regulation of cellular process)
2009-02-01 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2009-02-01 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2008-10-21 Added RELATION is a GO:0051224 (negative regulation of protein transport)
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2008-04-01 Added RELATION negatively regulates GO:0009306 (protein secretion)
2008-04-01 Updated RELATION is a GO:0050708 (regulation of protein secretion)
2008-04-01 Updated RELATION is a GO:0051048 (negative regulation of secretion)
2007-08-09 Added SYNONYM down regulation of protein secretion
2007-08-09 Added SYNONYM down-regulation of protein secretion
2007-08-09 Added SYNONYM downregulation of protein secretion
2007-08-09 Added SYNONYM inhibition of protein secretion
2007-08-09 Deleted SYNONYM down regulation of protein secretion
2007-08-09 Deleted SYNONYM down-regulation of protein secretion
2007-08-09 Deleted SYNONYM downregulation of protein secretion
2007-08-09 Deleted SYNONYM inhibition of protein secretion
2007-02-23 Added SYNONYM down regulation of protein secretion
2007-02-23 Added SYNONYM down-regulation of protein secretion
2007-02-23 Added SYNONYM downregulation of protein secretion
2007-02-23 Added SYNONYM inhibition of protein secretion
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a protein from a cell or group of cells.
2003-10-22 Added TERM negative regulation of protein secretion
2003-10-22 Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of a protein from a cell or group of cells.

Term

Timestamp Action Category Detail
2003-10-22 Added TERM negative regulation of protein secretion

Definition/synonyms

Timestamp Action Category Detail
2013-02-15 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2013-02-15 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2009-02-01 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
2009-02-01 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2007-08-09 Added SYNONYM down regulation of protein secretion
2007-08-09 Added SYNONYM down-regulation of protein secretion
2007-08-09 Added SYNONYM downregulation of protein secretion
2007-08-09 Added SYNONYM inhibition of protein secretion
2007-08-09 Deleted SYNONYM down regulation of protein secretion
2007-08-09 Deleted SYNONYM down-regulation of protein secretion
2007-08-09 Deleted SYNONYM downregulation of protein secretion
2007-08-09 Deleted SYNONYM inhibition of protein secretion
2007-02-23 Added SYNONYM down regulation of protein secretion
2007-02-23 Added SYNONYM down-regulation of protein secretion
2007-02-23 Added SYNONYM downregulation of protein secretion
2007-02-23 Added SYNONYM inhibition of protein secretion
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a protein from a cell or group of cells.
2003-10-22 Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of a protein from a cell or group of cells.

Relationships

Timestamp Action Category Detail
2014-10-10 Added RELATION is a GO:1903531 (negative regulation of secretion by cell)
2014-10-10 Deleted RELATION is a GO:0051048 (negative regulation of secretion)
2014-10-10 Deleted RELATION is a GO:0048523 (negative regulation of cellular process)
2009-06-16 Added RELATION is a GO:0048523 (negative regulation of cellular process)
2008-10-21 Added RELATION is a GO:0051224 (negative regulation of protein transport)
2008-04-01 Added RELATION negatively regulates GO:0009306 (protein secretion)
2008-04-01 Updated RELATION is a GO:0050708 (regulation of protein secretion)
2008-04-01 Updated RELATION is a GO:0051048 (negative regulation of secretion)
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