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GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

Term Information

ID GO:0050659
Name N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity
Ontology Molecular Function
Definition Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
Comment Consider instead annotating to the individual reactions: 'chondroitin 6-sulfotransferase activity ; GO:0008459' and 'dermatan 6-sulfotransferase activity ; GO:0036443'.
GONUTS GO:0050659 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related GalNAc4S-6ST
exact 3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity
exact N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.8.2.33
KEGG R02181
KEGG R07288
MetaCyc RXN-7953
MetaCyc RXN-7954

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0050659:
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Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0050659. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0050659 based on the entire annotation set Co-occurrence statistics for GO:0050659 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-10-23 Added XREF KEGG:R07288
2013-10-23 Added XREF KEGG:R02181
2013-10-23 Deleted XREF RHEA:11111
2011-09-16 Added XREF RHEA:11111
2009-05-21 Added XREF MetaCyc:RXN-7954
2009-05-21 Added XREF MetaCyc:RXN-7953
2008-05-13 Added DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2008-05-12 Deleted DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2008-04-27 Updated DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2008-04-01 Updated RELATION is a GO:0008146 (sulfotransferase activity)
2007-12-27 Updated DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2007-12-06 Deleted SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2007-12-06 Added SYNONYM 3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity
2007-12-06 Added SYNONYM GalNAc4S-6ST
2007-12-06 Added SYNONYM N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity
2007-12-06 Added XREF EC:2.8.2.33
2007-12-06 Deleted XREF EC:2.8.2.-
2007-08-09 Added SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2007-08-09 Deleted SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine 4-sulfate (in chondroitin sulfate) = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4,6-bissulfate. Functions on nonreducing terminal and internal GalNAc(4SO(4)) residues contained in chondroitin sulfate A and dermatan sulfate (chondroitin sulfate B).
2004-04-19 Added SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2004-04-16 Deleted SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2003-11-13 Added SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2003-10-09 Added XREF EC:2.8.2.-
2003-10-09 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate (PAPS) + N-acetyl-D-galactosamine 4-sulfate (in chondroitin sulfate) = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4,6-bissulfate. Functions on nonreducing terminal and internal GalNAc(4SO(4)) residues contained in chondroitin sulfate A and dermatan sulfate (chondroitin sulfate B).
2003-10-09 Added TERM N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

Term

Timestamp Action Category Detail
2003-10-09 Added TERM N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2008-05-12 Deleted DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2008-04-27 Updated DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2007-12-27 Updated DEFINITION Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2007-12-06 Deleted SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2007-12-06 Added SYNONYM 3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity
2007-12-06 Added SYNONYM GalNAc4S-6ST
2007-12-06 Added SYNONYM N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity
2007-08-09 Added SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2007-08-09 Deleted SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine 4-sulfate (in chondroitin sulfate) = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4,6-bissulfate. Functions on nonreducing terminal and internal GalNAc(4SO(4)) residues contained in chondroitin sulfate A and dermatan sulfate (chondroitin sulfate B).
2004-04-19 Added SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2004-04-16 Deleted SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2003-11-13 Added SYNONYM N-acetylgalactosamine 4-sulphate 6-O-sulphotransferase activity
2003-10-09 Added DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate (PAPS) + N-acetyl-D-galactosamine 4-sulfate (in chondroitin sulfate) = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4,6-bissulfate. Functions on nonreducing terminal and internal GalNAc(4SO(4)) residues contained in chondroitin sulfate A and dermatan sulfate (chondroitin sulfate B).

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008146 (sulfotransferase activity)

Cross-references

Timestamp Action Category Detail
2013-10-23 Added XREF KEGG:R07288
2013-10-23 Added XREF KEGG:R02181
2013-10-23 Deleted XREF RHEA:11111
2011-09-16 Added XREF RHEA:11111
2009-05-21 Added XREF MetaCyc:RXN-7954
2009-05-21 Added XREF MetaCyc:RXN-7953
2007-12-06 Added XREF EC:2.8.2.33
2007-12-06 Deleted XREF EC:2.8.2.-
2003-10-09 Added XREF EC:2.8.2.-
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