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GO:0050291 sphingosine N-acyltransferase activityCatalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae, either dihydrosphingosine (DHS) or phytosphingosine (PHS) can react with C26-fattyacyl-CoA to produce ceramide-I or ceramide-II (also called phytoceramide) respectively. In mammals, DHS is usually acylated with a C18 fatty acid group.
Term Information
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| Type | Synonym |
| exact | sphingosine acyltransferase activity |
| exact | ceramide synthetase activity |
| exact | ceramide synthase activity |
| exact | acyl-CoA:sphingosine N-acyltransferase activity |
| exact | dihydroceramide synthase activity |
| Database | ID |
| MetaCyc | SPHINGOSINE-N-ACYLTRANSFERASE-RXN |
| EC | 2.3.1.24 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016740 transferase activity | |||||
![]() | ![]() | ![]() | GO:0016746 transferase activity, transferring acyl groups | ||||
![]() | ![]() | ![]() | ![]() | GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0008415 acyltransferase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016410 N-acyltransferase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0050291 sphingosine N-acyltransferase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-25-04-02-21 |