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GO:0048102 autophagic cell death

Term Information

ID GO:0048102
Name autophagic cell death
Ontology Biological Process
Definition A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells.
PMID:18846107
GONUTS GO:0048102 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related type II programmed cell death
broad autophagic death
exact programmed cell death by macroautophagy
broad programmed cell death by autophagy

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating cell death and apoptosis using the new guidelinesLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000386 GO:0048102 autophagic cell death only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0007577 autophagic death (sensu Saccharomyces) CONSIDER GO:0048102
GO:0030465 autophagic death (sensu Fungi) CONSIDER GO:0048102

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0048102:
Relationship To GO:0048102 Child Term Child Term Name
Is a GO:0035071 salivary gland cell autophagic cell death
Has part GO:0016236 macroautophagy

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0048102. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0048102 based on the entire annotation set Co-occurrence statistics for GO:0048102 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-24 Deleted SYNONYM programmed cell death by autophagy
2013-04-24 Added SYNONYM programmed cell death by autophagy
2013-04-24 Added SYNONYM programmed cell death by macroautophagy
2009-08-31 Deleted SYNONYM autophagic death (sensu Fungi)
2009-08-31 Deleted SYNONYM autophagic death (sensu Saccharomyces)
2009-08-31 Added SYNONYM autophagic death
2009-03-13 Added SYNONYM type II programmed cell death
2009-02-09 Deleted DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2009-02-09 Added DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells.
2009-02-05 Deleted DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2009-02-05 Added DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2009-02-01 Added DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2009-02-01 Deleted DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2009-01-31 Deleted DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2009-01-31 Added DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2008-05-13 Added DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2008-05-12 Deleted DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2008-04-01 Updated RELATION is a GO:0012501 (programmed cell death)
2007-08-09 Added SYNONYM autophagic death (sensu Fungi)
2007-08-09 Added SYNONYM autophagic death (sensu Saccharomyces)
2007-08-09 Added SYNONYM programmed cell death by autophagy
2007-08-09 Deleted SYNONYM autophagic death (sensu Fungi)
2007-08-09 Deleted SYNONYM autophagic death (sensu Saccharomyces)
2007-08-09 Deleted SYNONYM programmed cell death by autophagy
2007-01-18 Deleted SYNONYM autophagic death (sensu the Fungi research community)
2007-01-18 Deleted SYNONYM autophagic death (sensu the Saccharomyces research community)
2007-01-18 Added SYNONYM autophagic death (sensu Fungi)
2007-01-18 Added SYNONYM autophagic death (sensu Saccharomyces)
2007-01-15 Deleted SYNONYM autophagic death (sensu Fungi)
2007-01-15 Deleted SYNONYM autophagic death (sensu Saccharomyces)
2007-01-15 Added SYNONYM autophagic death (sensu the Fungi research community)
2007-01-15 Added SYNONYM autophagic death (sensu the Saccharomyces research community)
2005-11-03 Added SYNONYM programmed cell death by autophagy
2005-08-10 Added SYNONYM autophagic death (sensu Fungi)
2005-08-10 Added SYNONYM autophagic death (sensu Saccharomyces)
2003-06-24 Added TERM autophagic cell death
2003-06-24 Added DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.

Term

Timestamp Action Category Detail
2003-06-24 Added TERM autophagic cell death

Definition/synonyms

Timestamp Action Category Detail
2013-04-24 Deleted SYNONYM programmed cell death by autophagy
2013-04-24 Added SYNONYM programmed cell death by autophagy
2013-04-24 Added SYNONYM programmed cell death by macroautophagy
2009-08-31 Deleted SYNONYM autophagic death (sensu Fungi)
2009-08-31 Deleted SYNONYM autophagic death (sensu Saccharomyces)
2009-08-31 Added SYNONYM autophagic death
2009-03-13 Added SYNONYM type II programmed cell death
2009-02-09 Deleted DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2009-02-09 Added DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells.
2009-02-05 Deleted DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2009-02-05 Added DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2009-02-01 Added DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2009-02-01 Deleted DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2009-01-31 Deleted DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2009-01-31 Added DEFINITION A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells
2008-05-13 Added DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2008-05-12 Deleted DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.
2007-08-09 Added SYNONYM autophagic death (sensu Fungi)
2007-08-09 Added SYNONYM autophagic death (sensu Saccharomyces)
2007-08-09 Added SYNONYM programmed cell death by autophagy
2007-08-09 Deleted SYNONYM autophagic death (sensu Fungi)
2007-08-09 Deleted SYNONYM autophagic death (sensu Saccharomyces)
2007-08-09 Deleted SYNONYM programmed cell death by autophagy
2007-01-18 Deleted SYNONYM autophagic death (sensu the Fungi research community)
2007-01-18 Deleted SYNONYM autophagic death (sensu the Saccharomyces research community)
2007-01-18 Added SYNONYM autophagic death (sensu Fungi)
2007-01-18 Added SYNONYM autophagic death (sensu Saccharomyces)
2007-01-15 Deleted SYNONYM autophagic death (sensu Fungi)
2007-01-15 Deleted SYNONYM autophagic death (sensu Saccharomyces)
2007-01-15 Added SYNONYM autophagic death (sensu the Fungi research community)
2007-01-15 Added SYNONYM autophagic death (sensu the Saccharomyces research community)
2005-11-03 Added SYNONYM programmed cell death by autophagy
2005-08-10 Added SYNONYM autophagic death (sensu Fungi)
2005-08-10 Added SYNONYM autophagic death (sensu Saccharomyces)
2003-06-24 Added DEFINITION Destruction of a cell by its own lysosomal contents. This type of programmed cell death is seen when entire tissues, or parts thereof, are committed to destruction, and occurs by the formation of multiple acidic autophagic vacuoles within the doomed cells.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0012501 (programmed cell death)
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