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GO:0048011 neurotrophin TRK receptor signaling pathway

Term Information

ID GO:0048011
Name neurotrophin TRK receptor signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
PMID:12065629
GONUTS GO:0048011 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow TrkB signaling pathway
narrow TrkC signaling pathway
narrow TrkA signaling pathway
exact tropomyosin-receptor-kinase signaling

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0001010 GO:0070848 response to growth factor never_in_taxon 2, 2157, 4751 Fungi or Bacteria or Archaea
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR026682

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0048011:
Relationship To GO:0048011 Child Term Child Term Name
Regulates GO:0051386 regulation of neurotrophin TRK receptor signaling pathway
Negatively regulates GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway
Positively regulates GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0048011. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0048011 based on the entire annotation set Co-occurrence statistics for GO:0048011 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-05-17 Deleted SYNONYM nerve growth factor receptor signaling pathway
2013-05-17 Added SYNONYM tropomyosin-receptor-kinase signaling
2013-05-17 Deleted SYNONYM NGF receptor signaling pathway
2013-05-17 Deleted SYNONYM nerve growth factor receptor signalling pathway
2013-05-17 Deleted SYNONYM NGF receptor signalling pathway
2013-03-29 Added SYNONYM NGF receptor signaling pathway
2013-03-29 Added SYNONYM NGF receptor signalling pathway
2013-03-29 Added SYNONYM TrkC signaling pathway
2013-03-29 Added RELATION is a GO:0038179 (neurotrophin signaling pathway)
2013-03-29 Deleted SYNONYM NGF receptor signalling pathway
2013-03-29 Deleted SYNONYM nerve growth factor receptor signalling pathway
2013-03-29 Deleted SYNONYM NGF receptor signaling pathway
2013-03-29 Added SYNONYM nerve growth factor receptor signaling pathway
2013-03-29 Added SYNONYM nerve growth factor receptor signalling pathway
2013-03-29 Added SYNONYM TrkA signaling pathway
2013-03-29 Added SYNONYM TrkB signaling pathway
2013-03-29 Updated TERM neurotrophin TRK receptor signaling pathway
2013-03-29 Deleted DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.
2013-03-29 Added DEFINITION A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.
2008-04-01 Updated RELATION is a GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway)
2007-08-09 Added SYNONYM NGF receptor signaling pathway
2007-08-09 Added SYNONYM NGF receptor signalling pathway
2007-08-09 Added SYNONYM nerve growth factor receptor signalling pathway
2007-08-09 Deleted SYNONYM NGF receptor signaling pathway
2007-08-09 Deleted SYNONYM NGF receptor signalling pathway
2007-08-09 Deleted SYNONYM nerve growth factor receptor signalling pathway
2005-06-27 Added SYNONYM nerve growth factor receptor signalling pathway
2004-04-19 Added SYNONYM NGF receptor signaling pathway
2004-04-19 Added SYNONYM NGF receptor signalling pathway
2004-04-16 Deleted SYNONYM NGF receptor signaling pathway
2004-04-16 Deleted SYNONYM NGF receptor signalling pathway
2004-02-12 Added SYNONYM NGF receptor signaling pathway
2004-02-12 Updated TERM nerve growth factor receptor signaling pathway
2003-11-13 Added SYNONYM NGF receptor signalling pathway
2002-11-27 Added DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.
2002-07-11 Added TERM NGF receptor signaling pathway

Term

Timestamp Action Category Detail
2013-03-29 Updated TERM neurotrophin TRK receptor signaling pathway
2004-02-12 Updated TERM nerve growth factor receptor signaling pathway
2002-07-11 Added TERM NGF receptor signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2013-05-17 Deleted SYNONYM nerve growth factor receptor signaling pathway
2013-05-17 Added SYNONYM tropomyosin-receptor-kinase signaling
2013-05-17 Deleted SYNONYM NGF receptor signaling pathway
2013-05-17 Deleted SYNONYM nerve growth factor receptor signalling pathway
2013-05-17 Deleted SYNONYM NGF receptor signalling pathway
2013-03-29 Added SYNONYM NGF receptor signaling pathway
2013-03-29 Added SYNONYM NGF receptor signalling pathway
2013-03-29 Added SYNONYM TrkC signaling pathway
2013-03-29 Deleted SYNONYM NGF receptor signalling pathway
2013-03-29 Deleted SYNONYM nerve growth factor receptor signalling pathway
2013-03-29 Deleted SYNONYM NGF receptor signaling pathway
2013-03-29 Added SYNONYM nerve growth factor receptor signaling pathway
2013-03-29 Added SYNONYM nerve growth factor receptor signalling pathway
2013-03-29 Added SYNONYM TrkA signaling pathway
2013-03-29 Added SYNONYM TrkB signaling pathway
2013-03-29 Deleted DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.
2013-03-29 Added DEFINITION A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
2008-05-13 Added DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.
2008-05-12 Deleted DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.
2007-08-09 Added SYNONYM NGF receptor signaling pathway
2007-08-09 Added SYNONYM NGF receptor signalling pathway
2007-08-09 Added SYNONYM nerve growth factor receptor signalling pathway
2007-08-09 Deleted SYNONYM NGF receptor signaling pathway
2007-08-09 Deleted SYNONYM NGF receptor signalling pathway
2007-08-09 Deleted SYNONYM nerve growth factor receptor signalling pathway
2005-06-27 Added SYNONYM nerve growth factor receptor signalling pathway
2004-04-19 Added SYNONYM NGF receptor signaling pathway
2004-04-19 Added SYNONYM NGF receptor signalling pathway
2004-04-16 Deleted SYNONYM NGF receptor signaling pathway
2004-04-16 Deleted SYNONYM NGF receptor signalling pathway
2004-02-12 Added SYNONYM NGF receptor signaling pathway
2003-11-13 Added SYNONYM NGF receptor signalling pathway
2002-11-27 Added DEFINITION The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands.

Relationships

Timestamp Action Category Detail
2013-03-29 Added RELATION is a GO:0038179 (neurotrophin signaling pathway)
2008-04-01 Updated RELATION is a GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway)
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