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GO:0047787 delta4-3-oxosteroid 5beta-reductase activityCatalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+.
Term Information
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| Type | Synonym |
| exact | delta-4-3-oxosteroid 5-beta-reductase activity |
| exact | cortisone beta-reductase activity |
| exact | cortisone b-reductase activity |
| exact | cholestenone 5b-reductase activity |
| exact | cholestenone 5-beta-reductase activity |
| exact | testosterone 5beta-reductase activity |
| exact | steroid 5beta-reductase activity |
| exact | delta4-hydrogenase activity |
| exact | delta4-5beta-reductase activity |
| exact | cortisone delta4-5beta-reductase activity |
| exact | cortisone 5beta-reductase activity |
| exact | cholestenone 5beta-reductase activity |
| exact | androstenedione 5beta-reductase activity |
| exact | 5beta-reductase activity |
| exact | 5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity |
| exact | 4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity |
| exact | 3-oxo-delta4-steroid 5beta-reductase activity |
| exact | 3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity |
| exact | delta4-3-ketosteroid 5beta-reductase activity |
| exact | testosterone 5-beta-reductase activity |
| exact | steroid 5-beta-reductase activity |
| exact | delta(4)-hydrogenase activity |
| exact | delta(4)-5-beta-reductase activity |
| exact | 3-oxo-Delta(4)-steroid 5-beta-reductase activity |
| broad | 5-beta-reductase activity |
| exact | androstenedione 5-beta-reductase activity |
| exact | cortisone 5-beta-reductase activity |
| exact | cortisone delta(4)-5-beta-reductase activity |
| exact | delta(4)-3-ketosteroid 5-beta-reductase activity |
| Database | ID |
| MetaCyc | CORTISONE-BETA-REDUCTASE-RXN |
| MetaCyc | CHOLESTENONE-5-BETA-REDUCTASE-RXN |
| EC | 1.3.1.3 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016491 oxidoreductase activity | |||
![]() | ![]() | ![]() | GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors | ||
![]() | ![]() | ![]() | ![]() | GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0047787 delta4-3-oxosteroid 5beta-reductase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-23-04-03-36 |