
GO:0047749 cholestanetriol 26monooxygenase activity
Term Information
ID 
GO:0047749 
Name 
cholestanetriol 26monooxygenase activity 
Ontology 
Molecular Function 
Definition 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP+ + H2O.

GONUTS 
GO:0047749 Wiki Page 
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Click on the icon for more details.
Type 
Synonym 
exact 
5betacholestane3alpha,7alpha,12alphatriol hydroxylase activity 
related 
sterol 27hydroxylase activity 
broad 
sterol 26hydroxylase activity 
narrow 
cytochrome P450 27A1' activity 
related 
cholesterol 27hydroxylase activity 
broad 
5betacholestane3alpha,7alpha,12alphatriol hydroxylase activity 
exact 
5betacholestane3alpha,7alpha,12alphatriol 26hydroxylase activity 
exact 
5betacholestane3alpha,7alpha,12alphatriol,NADPH:oxygen oxidoreductase (26hydroxylating) 
related 
CYP27A 
related 
CYP27A1 
exact 
cholestanetriol 26hydroxylase activity 
exact 
5betacholestane3alpha,7alpha,12alphatriol 26hydroxylase activity 
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines 
Annotating to catalytic activities using the IPI evidence code  Link 
Describing enzyme functions that catalyse multistage reactions  Link 
Crossreferences
Database 
ID 
EC 
1.14.13.15 
MetaCyc 
CHOLESTANETRIOL26MONOOXYGENASERXN 
RHEA 
14376 
Ancestor Chart
This chart is interactive; you can click on the term boxes and legend for more information.
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0047749:
Protein Annotation
Cooccurring Terms
These tables show the number of times the term listed in the table has been coannotated with GO:0047749. The terms are listed in descending order of number of times the term has been coannotated.
The table on the left is calculated using both electronic and manualevidenced annotations, while the table on the right is calculated using only manualevidenced annotations.
Change Log
All changes
Timestamp 
Action 
Category 
Detail 
20110916 
Added 
XREF 
RHEA:14376 
20080513 
Added 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP+ + H2O. 
20080512 
Deleted 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP+ + H2O. 
20080401 
Updated 
RELATION 
is a GO:0016709 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen) 
20071108 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol 26hydroxylase activity 
20071108 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol hydroxylase activity 
20071108 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol,NADPH:oxygen oxidoreductase (26hydroxylating) 
20071108 
Added 
SYNONYM 
CYP27A 
20071108 
Added 
SYNONYM 
CYP27A1 
20070906 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol 26hydroxylase activity 
20070906 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol hydroxylase activity 
20070906 
Added 
SYNONYM 
cholesterol 27hydroxylase activity 
20070906 
Added 
SYNONYM 
cytochrome P450 27A1' activity 
20070906 
Added 
SYNONYM 
sterol 26hydroxylase activity 
20070906 
Added 
SYNONYM 
sterol 27hydroxylase activity 
20070809 
Added 
SYNONYM 
cholestanetriol 26hydroxylase activity 
20070809 
Deleted 
SYNONYM 
cholestanetriol 26hydroxylase activity 
20040419 
Added 
SYNONYM 
cholestanetriol 26hydroxylase activity 
20031031 
Updated 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP+ + H2O. 
20031027 
Added 
XREF 
MetaCyc:CHOLESTANETRIOL26MONOOXYGENASERXN 
20031024 
Updated 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP + H2O. 
20030828 
Added 
XREF 
EC:1.14.13.15 
20030828 
Added 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP + H2O. 
20030828 
Added 
TERM 
cholestanetriol 26monooxygenase activity 
Term
Timestamp 
Action 
Category 
Detail 
20030828 
Added 
TERM 
cholestanetriol 26monooxygenase activity 
Definition/synonyms
Timestamp 
Action 
Category 
Detail 
20080513 
Added 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP+ + H2O. 
20080512 
Deleted 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP+ + H2O. 
20071108 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol 26hydroxylase activity 
20071108 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol hydroxylase activity 
20071108 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol,NADPH:oxygen oxidoreductase (26hydroxylating) 
20071108 
Added 
SYNONYM 
CYP27A 
20071108 
Added 
SYNONYM 
CYP27A1 
20070906 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol 26hydroxylase activity 
20070906 
Added 
SYNONYM 
5betacholestane3alpha,7alpha,12alphatriol hydroxylase activity 
20070906 
Added 
SYNONYM 
cholesterol 27hydroxylase activity 
20070906 
Added 
SYNONYM 
cytochrome P450 27A1' activity 
20070906 
Added 
SYNONYM 
sterol 26hydroxylase activity 
20070906 
Added 
SYNONYM 
sterol 27hydroxylase activity 
20070809 
Added 
SYNONYM 
cholestanetriol 26hydroxylase activity 
20070809 
Deleted 
SYNONYM 
cholestanetriol 26hydroxylase activity 
20040419 
Added 
SYNONYM 
cholestanetriol 26hydroxylase activity 
20031031 
Updated 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP+ + H2O. 
20031024 
Updated 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP + H2O. 
20030828 
Added 
DEFINITION 
Catalysis of the reaction: 5betacholestane3alpha,7alpha,12alphatriol + NADPH + O2 = 5betacholestane3alpha,7alpha,12alpha,26tetraol + NADP + H2O. 
Relationships
Timestamp 
Action 
Category 
Detail 
20080401 
Updated 
RELATION 
is a GO:0016709 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen) 
Crossreferences
Timestamp 
Action 
Category 
Detail 
20110916 
Added 
XREF 
RHEA:14376 
20031027 
Added 
XREF 
MetaCyc:CHOLESTANETRIOL26MONOOXYGENASERXN 
20030828 
Added 
XREF 
EC:1.14.13.15 
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14ms
