spacer

GO:0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity

Term Information

ID GO:0047480
Name UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Ontology Molecular Function
Definition Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
Comment Note that the enzyme UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase also has UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (GO:0008766).
GONUTS GO:0047480 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
exact UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity
exact UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)
related MurF synthetase activity
exact UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
exact UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
exact UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity
exact UDPacetylmuramoylpentapeptide synthetase activity
exact UDP-MurNAc-pentapeptide synthetase activity
exact UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity
exact UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity
exact UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity
exact uridine diphosphoacetylmuramoylpentapeptide synthetase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 6.3.2.10
MetaCyc 6.3.2.10-RXN
RHEA 16088

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0047480:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0047480. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0047480 based on the entire annotation set Co-occurrence statistics for GO:0047480 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:16088
2008-05-13 Added DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2008-04-01 Updated RELATION is a GO:0016881 (acid-amino acid ligase activity)
2007-11-08 Added SYNONYM UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)
2007-09-06 Added SYNONYM MurF synthetase activity
2007-09-06 Added SYNONYM UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity
2007-09-06 Added SYNONYM UDP-MurNAc-pentapeptide synthetase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2007-09-06 Added SYNONYM UDPacetylmuramoylpentapeptide synthetase activity
2007-09-06 Added SYNONYM uridine diphosphoacetylmuramoylpentapeptide synthetase activity
2007-08-09 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2007-08-09 Added SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2007-08-09 Deleted SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2007-08-09 Deleted SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2004-04-19 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2004-04-19 Added SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2004-04-16 Deleted SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2004-04-16 Deleted SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-10-27 Added SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-10-27 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2003-10-27 Added XREF MetaCyc:6.3.2.10-RXN
2003-09-09 Updated TERM UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-09-06 Updated TERM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-08-19 Added XREF EC:6.3.2.10
2003-08-19 Added DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2003-08-19 Added TERM UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity

Term

Timestamp Action Category Detail
2003-09-09 Updated TERM UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-09-06 Updated TERM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-08-19 Added TERM UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2007-11-08 Added SYNONYM UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)
2007-09-06 Added SYNONYM MurF synthetase activity
2007-09-06 Added SYNONYM UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity
2007-09-06 Added SYNONYM UDP-MurNAc-pentapeptide synthetase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity
2007-09-06 Added SYNONYM UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2007-09-06 Added SYNONYM UDPacetylmuramoylpentapeptide synthetase activity
2007-09-06 Added SYNONYM uridine diphosphoacetylmuramoylpentapeptide synthetase activity
2007-08-09 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2007-08-09 Added SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2007-08-09 Deleted SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2007-08-09 Deleted SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2004-04-19 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2004-04-19 Added SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2004-04-16 Deleted SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2004-04-16 Deleted SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-10-27 Added SYNONYM UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
2003-10-27 Added SYNONYM UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
2003-08-19 Added DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016881 (acid-amino acid ligase activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:16088
2003-10-27 Added XREF MetaCyc:6.3.2.10-RXN
2003-08-19 Added XREF EC:6.3.2.10
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
13ms