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GO:0047035 testosterone dehydrogenase (NAD+) activity

Term Information

ID GO:0047035
Name testosterone dehydrogenase (NAD+) activity
Ontology Molecular Function
Definition Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.
Secondary IDs GO:0050327
GONUTS GO:0047035 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact testosterone 17b-dehydrogenase activity
exact testosterone 17beta-dehydrogenase activity
exact testosterone 17-beta-dehydrogenase (NAD+) activity
broad 3alpha,17beta-hydroxy steroid dehydrogenase activity
broad 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
broad 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
broad 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
broad 17-beta-HSD activity
related 17beta-HSD
broad 17-ketoreductase activity
exact 17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity
related 3alpha(17beta)-HSD

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.1.1.239
KEGG R01836
MetaCyc 1.1.1.239-RXN
MetaCyc TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN
RHEA 14932
Wikipedia 3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0047035:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0047035. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0047035 based on the entire annotation set Co-occurrence statistics for GO:0047035 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-10-02 Added XREF KEGG:R01836
2013-10-02 Added XREF MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN
2013-10-02 Added SECONDARY GO:0050327 (testosterone 17-beta-dehydrogenase (NAD+) activity)
2013-10-02 Deleted DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2013-10-02 Added DEFINITION Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.
2013-10-02 Added SYNONYM 17-beta-HSD activity
2013-10-02 Added SYNONYM 17beta-HSD
2013-10-02 Added SYNONYM 17-ketoreductase activity
2013-10-02 Added SYNONYM 17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity
2013-10-02 Added SYNONYM testosterone 17b-dehydrogenase activity
2013-10-02 Added SYNONYM testosterone 17beta-dehydrogenase activity
2013-10-02 Added SYNONYM testosterone 17-beta-dehydrogenase (NAD+) activity
2011-09-16 Added XREF RHEA:14932
2011-04-18 Added RELATION is a GO:0033764 (steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2011-04-18 Deleted RELATION is a GO:0030283 (testosterone dehydrogenase [NAD(P)] activity)
2011-02-15 Added RELATION is a GO:0030283 (testosterone dehydrogenase [NAD(P)] activity)
2011-02-15 Deleted RELATION is a GO:0033764 (steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2011-02-15 Added SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 Added SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2011-02-15 Added SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 Added SYNONYM 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
2011-02-15 Deleted SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 Deleted SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 Deleted SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2011-02-15 Updated TERM testosterone dehydrogenase (NAD+) activity
2009-02-25 Added XREF Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)
2008-05-13 Added DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2008-04-01 Updated RELATION is a GO:0033764 (steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2007-11-08 Added SYNONYM 3alpha(17beta)-HSD
2007-11-08 Added SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2007-11-08 Added SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2007-11-08 Added SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2004-01-07 Updated TERM 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
2003-10-31 Updated DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + androst-4-ene-3,17-dione.
2003-10-27 Added XREF MetaCyc:1.1.1.239-RXN
2003-09-09 Updated TERM 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD) activity
2003-09-06 Updated TERM 3-alpha (17-beta)-hydroxysteroid dehydrogenase (NAD) activity
2003-08-19 Added XREF EC:1.1.1.239
2003-08-19 Added DEFINITION Catalysis of the reaction: NAD + testosterone = NADH + androst-4-ene-3,17-dione.
2003-08-19 Added TERM 3-alpha (17-beta)-hydroxysteroid dehydrogenase (NAD+) activity

Term

Timestamp Action Category Detail
2011-02-15 Updated TERM testosterone dehydrogenase (NAD+) activity
2004-01-07 Updated TERM 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
2003-09-09 Updated TERM 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD) activity
2003-09-06 Updated TERM 3-alpha (17-beta)-hydroxysteroid dehydrogenase (NAD) activity
2003-08-19 Added TERM 3-alpha (17-beta)-hydroxysteroid dehydrogenase (NAD+) activity

Definition/synonyms

Timestamp Action Category Detail
2013-10-02 Deleted DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2013-10-02 Added DEFINITION Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.
2013-10-02 Added SYNONYM 17-beta-HSD activity
2013-10-02 Added SYNONYM 17beta-HSD
2013-10-02 Added SYNONYM 17-ketoreductase activity
2013-10-02 Added SYNONYM 17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity
2013-10-02 Added SYNONYM testosterone 17b-dehydrogenase activity
2013-10-02 Added SYNONYM testosterone 17beta-dehydrogenase activity
2013-10-02 Added SYNONYM testosterone 17-beta-dehydrogenase (NAD+) activity
2011-02-15 Added SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 Added SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2011-02-15 Added SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 Added SYNONYM 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
2011-02-15 Deleted SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 Deleted SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 Deleted SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2007-11-08 Added SYNONYM 3alpha(17beta)-HSD
2007-11-08 Added SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2007-11-08 Added SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2007-11-08 Added SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2003-10-31 Updated DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + androst-4-ene-3,17-dione.
2003-08-19 Added DEFINITION Catalysis of the reaction: NAD + testosterone = NADH + androst-4-ene-3,17-dione.

Relationships

Timestamp Action Category Detail
2011-04-18 Added RELATION is a GO:0033764 (steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2011-04-18 Deleted RELATION is a GO:0030283 (testosterone dehydrogenase [NAD(P)] activity)
2011-02-15 Added RELATION is a GO:0030283 (testosterone dehydrogenase [NAD(P)] activity)
2011-02-15 Deleted RELATION is a GO:0033764 (steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2008-04-01 Updated RELATION is a GO:0033764 (steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2013-10-02 Added XREF KEGG:R01836
2013-10-02 Added XREF MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN
2011-09-16 Added XREF RHEA:14932
2009-02-25 Added XREF Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)
2003-10-27 Added XREF MetaCyc:1.1.1.239-RXN
2003-08-19 Added XREF EC:1.1.1.239

Other

Timestamp Action Category Detail
2013-10-02 Added SECONDARY GO:0050327 (testosterone 17-beta-dehydrogenase (NAD+) activity)
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