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GO:0047011 2-dehydropantolactone reductase (A-specific) activity

Term Information

ID GO:0047011
Name 2-dehydropantolactone reductase (A-specific) activity
Ontology Molecular Function
Definition Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
GONUTS GO:0047011 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact 2-dehydropantoyl-lactone reductase (A-specific) activity
broad 2-oxopantoyl lactone reductase
exact (R)-pantolactone:NADP+ oxidoreductase (A-specific)
broad ketopantoyl lactone reductase activity
broad 2-ketopantoyl lactone reductase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.1.1.168
MetaCyc 1.1.1.168-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0047011:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0047011. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0047011 based on the entire annotation set Co-occurrence statistics for GO:0047011 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-10-02 Deleted XREF RHEA:18984
2013-10-02 Added RELATION is a GO:0036441 (2-dehydropantolactone reductase activity)
2013-10-02 Deleted RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2011-09-16 Added XREF RHEA:18984
2008-05-13 Added DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2008-03-11 Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2007-11-08 Added SYNONYM (R)-pantolactone:NADP+ oxidoreductase (A-specific)
2007-11-08 Added SYNONYM 2-oxopantoyl lactone reductase
2007-09-06 Added SYNONYM 2-dehydropantoyl-lactone reductase (A-specific) activity
2007-09-06 Added SYNONYM 2-ketopantoyl lactone reductase activity
2007-09-06 Added SYNONYM ketopantoyl lactone reductase activity
2006-01-26 Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
2003-10-31 Updated DEFINITION Catalysis of the reaction: NADP+ + pantoyl lactone = NADPH + 2-dehydropantoyl lactone.
2003-10-27 Added XREF MetaCyc:1.1.1.168-RXN
2003-08-19 Added XREF EC:1.1.1.168
2003-08-19 Added DEFINITION Catalysis of the reaction: NADP + pantoyl lactone = NADPH + 2-dehydropantoyl lactone.
2003-08-19 Added TERM 2-dehydropantolactone reductase (A-specific) activity

Term

Timestamp Action Category Detail
2003-08-19 Added TERM 2-dehydropantolactone reductase (A-specific) activity

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-03-11 Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2007-11-08 Added SYNONYM (R)-pantolactone:NADP+ oxidoreductase (A-specific)
2007-11-08 Added SYNONYM 2-oxopantoyl lactone reductase
2007-09-06 Added SYNONYM 2-dehydropantoyl-lactone reductase (A-specific) activity
2007-09-06 Added SYNONYM 2-ketopantoyl lactone reductase activity
2007-09-06 Added SYNONYM ketopantoyl lactone reductase activity
2006-01-26 Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
2003-10-31 Updated DEFINITION Catalysis of the reaction: NADP+ + pantoyl lactone = NADPH + 2-dehydropantoyl lactone.
2003-08-19 Added DEFINITION Catalysis of the reaction: NADP + pantoyl lactone = NADPH + 2-dehydropantoyl lactone.

Relationships

Timestamp Action Category Detail
2013-10-02 Added RELATION is a GO:0036441 (2-dehydropantolactone reductase activity)
2013-10-02 Deleted RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2013-10-02 Deleted XREF RHEA:18984
2011-09-16 Added XREF RHEA:18984
2003-10-27 Added XREF MetaCyc:1.1.1.168-RXN
2003-08-19 Added XREF EC:1.1.1.168
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