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GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Term Information

ID GO:0046934
Name phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).
GONUTS GO:0046934 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow phosphatidylinositol 3-kinase activity, class II
exact ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity
narrow phosphatidylinositol 3-kinase, class I, catalyst activity
narrow phosphatidylinositol 3-kinase activity, class I
narrow type I phosphoinositide 3-kinase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.1.153
KEGG R04545
MetaCyc 2.7.1.153-RXN
RHEA 21295

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0016305 phosphatidylinositol 3-kinase activity, class II CONSIDER GO:0046934
GO:0015072 phosphatidylinositol 3-kinase, class I, catalyst activity REPLACEDBY GO:0046934
GO:0016304 phosphatidylinositol 3-kinase activity, class I REPLACEDBY GO:0046934

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046934:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0046934. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0046934 based on the entire annotation set Co-occurrence statistics for GO:0046934 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-01-15 Added RELATION is a GO:0035004 (phosphatidylinositol 3-kinase activity)
2011-10-28 Added RELATION is a GO:0052813 (phosphatidylinositol bisphosphate kinase activity)
2011-10-28 Deleted RELATION is a GO:0035004 (phosphatidylinositol 3-kinase activity)
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
2010-10-11 Added DEFINITION Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).
2010-10-11 Added XREF RHEA:21295
2010-10-11 Added XREF KEGG:R04545
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
2008-04-01 Updated RELATION is a GO:0035004 (phosphatidylinositol 3-kinase activity)
2007-11-08 Added SYNONYM ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity
2007-09-06 Added SYNONYM type I phosphoinositide 3-kinase activity
2007-08-09 Added SYNONYM phosphatidylinositol 3-kinase, class I, catalyst activity
2007-08-09 Added SYNONYM phosphatidylinositol 3-kinase activity, class I
2007-08-09 Added SYNONYM phosphatidylinositol 3-kinase activity, class II
2007-08-09 Deleted SYNONYM phosphatidylinositol 3-kinase activity, class I
2007-08-09 Deleted SYNONYM phosphatidylinositol 3-kinase activity, class II
2007-08-09 Deleted SYNONYM phosphatidylinositol 3-kinase, class I, catalyst activity
2005-08-10 Added SYNONYM phosphatidylinositol 3-kinase activity, class I
2005-08-10 Added SYNONYM phosphatidylinositol 3-kinase activity, class II
2005-08-10 Added SYNONYM phosphatidylinositol 3-kinase, class I, catalyst activity
2003-10-27 Added XREF MetaCyc:2.7.1.153-RXN
2003-08-28 Added XREF EC:2.7.1.153
2003-05-08 Added TERM phosphatidylinositol-4,5-bisphosphate 3-kinase activity
2003-05-08 Added DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.

Term

Timestamp Action Category Detail
2003-05-08 Added TERM phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
2010-10-11 Added DEFINITION Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
2007-11-08 Added SYNONYM ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity
2007-09-06 Added SYNONYM type I phosphoinositide 3-kinase activity
2007-08-09 Added SYNONYM phosphatidylinositol 3-kinase, class I, catalyst activity
2007-08-09 Added SYNONYM phosphatidylinositol 3-kinase activity, class I
2007-08-09 Added SYNONYM phosphatidylinositol 3-kinase activity, class II
2007-08-09 Deleted SYNONYM phosphatidylinositol 3-kinase activity, class I
2007-08-09 Deleted SYNONYM phosphatidylinositol 3-kinase activity, class II
2007-08-09 Deleted SYNONYM phosphatidylinositol 3-kinase, class I, catalyst activity
2005-08-10 Added SYNONYM phosphatidylinositol 3-kinase activity, class I
2005-08-10 Added SYNONYM phosphatidylinositol 3-kinase activity, class II
2005-08-10 Added SYNONYM phosphatidylinositol 3-kinase, class I, catalyst activity
2003-05-08 Added DEFINITION Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.

Relationships

Timestamp Action Category Detail
2012-01-15 Added RELATION is a GO:0035004 (phosphatidylinositol 3-kinase activity)
2011-10-28 Added RELATION is a GO:0052813 (phosphatidylinositol bisphosphate kinase activity)
2011-10-28 Deleted RELATION is a GO:0035004 (phosphatidylinositol 3-kinase activity)
2008-04-01 Updated RELATION is a GO:0035004 (phosphatidylinositol 3-kinase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:21295
2010-10-11 Added XREF KEGG:R04545
2003-10-27 Added XREF MetaCyc:2.7.1.153-RXN
2003-08-28 Added XREF EC:2.7.1.153
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