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GO:0046718 viral entry into host cell

Term Information

ID GO:0046718
Name viral entry into host cell
Ontology Biological Process
Definition The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
Comment Viral attachment to the host cell is not part of viral entry in GO because virus attachment does not always lead to viral entry: attachment can also result in the virion being carried by the host cell to another location.
Secondary IDs GO:0019063
GONUTS GO:0046718 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact phage translocation
exact virion penetration into host cell
exact entry of virus into host cell
exact virion penetration
exact virus entry into host cell
exact viral penetration

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating gene products that interact with other organisms Link

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
Viral ProcessesLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_virus30

Cross-references

Database ID
InterPro IPR004957
InterPro IPR005563
InterPro IPR006777
InterPro IPR009113
InterPro IPR015960
InterPro IPR015961
InterPro IPR015962
UniProtKB-KW Viral penetration into host cytoplasm
UniProtKB-KW Virus entry into host cell
VZ 936

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0019059 initiation of viral infection CONSIDER GO:0046718
GO:0019066 translocation of virus into host cell REPLACEDBY GO:0046718

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046718:
Relationship To GO:0046718 Child Term Child Term Name
Is a GO:0044694 pore-mediated entry of viral genome into host cell
Is a GO:0039667 viral entry into host cell via pilus retraction
Part of GO:0039663 membrane fusion involved in viral entry into host cell
Part of GO:0039664 lysis of host organelle involved in viral entry into host cell
Part of GO:0039665 permeabilization of host organelle membrane involved in viral entry into host cell
Part of GO:0075509 endocytosis involved in viral entry into host cell
Is a GO:0039678 viral genome ejection through host cell envelope
Part of GO:0075510 macropinocytosis involved in viral entry into host cell
Regulates GO:0046596 regulation of viral entry into host cell
Negatively regulates GO:0046597 negative regulation of viral entry into host cell
Positively regulates GO:0046598 positive regulation of viral entry into host cell

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0046718. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0046718 based on the entire annotation set Co-occurrence statistics for GO:0046718 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-03-07 Added SLIM goslim_virus
2013-12-04 Deleted RELATION is a GO:0016032 (viral process)
2013-11-27 Added DEFINITION The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
2013-11-27 Deleted DEFINITION The process that occurs after viral attachment by which a virion, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
2013-09-27 Added RELATION part of GO:0019058 (viral life cycle)
2013-08-31 Added SYNONYM virus entry into host cell
2013-07-12 Added RELATION is a GO:0016032 (viral process)
2013-07-12 Deleted RELATION is a GO:0019048 (modulation by virus of host morphology or physiology)
2012-09-16 Deleted RELATION part of GO:0019059 (initiation of viral infection)
2012-08-24 Deleted RELATION is a GO:0022415 (viral reproductive process)
2012-03-29 Added SECONDARY GO:0019063 (virion penetration into host cell)
2012-03-29 Added XREF VZ:936
2012-03-29 Added RELATION is a GO:0022415 (viral reproductive process)
2012-03-29 Added RELATION is a GO:0019048 (modulation by virus of host morphology or physiology)
2012-03-29 Added SYNONYM virion penetration
2012-03-29 Deleted SYNONYM viral entry into host cell
2012-03-29 Added SYNONYM entry of virus into host cell
2012-03-29 Added SYNONYM viral penetration
2012-03-29 Added SYNONYM virion penetration into host cell
2012-03-29 Added SYNONYM phage translocation
2012-03-29 Updated TERM viral entry into host cell
2012-03-29 Deleted DEFINITION The process in which a virion enters a host cell, including virion attachment and penetration.
2012-03-29 Added DEFINITION The process that occurs after viral attachment by which a virion, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
2010-12-12 Added DEFINITION The process in which a virion enters a host cell, including virion attachment and penetration.
2010-12-12 Deleted DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.
2008-05-13 Added DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.
2008-05-12 Deleted DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.
2008-04-01 Updated RELATION is a GO:0030260 (entry into host cell)
2008-04-01 Updated RELATION part of GO:0019059 (initiation of viral infection)
2007-08-09 Added SYNONYM viral entry into host cell
2007-08-09 Deleted SYNONYM viral entry into host cell
2005-12-10 Added SYNONYM viral entry into host cell
2005-12-10 Updated TERM entry of virus into host cell
2005-02-03 Updated TERM viral entry into host cell
2003-03-26 Added DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.
2002-12-06 Added TERM viral entry

Term

Timestamp Action Category Detail
2012-03-29 Updated TERM viral entry into host cell
2005-12-10 Updated TERM entry of virus into host cell
2005-02-03 Updated TERM viral entry into host cell
2002-12-06 Added TERM viral entry

Definition/synonyms

Timestamp Action Category Detail
2013-11-27 Added DEFINITION The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
2013-11-27 Deleted DEFINITION The process that occurs after viral attachment by which a virion, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
2013-08-31 Added SYNONYM virus entry into host cell
2012-03-29 Added SYNONYM virion penetration
2012-03-29 Deleted SYNONYM viral entry into host cell
2012-03-29 Added SYNONYM entry of virus into host cell
2012-03-29 Added SYNONYM viral penetration
2012-03-29 Added SYNONYM virion penetration into host cell
2012-03-29 Added SYNONYM phage translocation
2012-03-29 Deleted DEFINITION The process in which a virion enters a host cell, including virion attachment and penetration.
2012-03-29 Added DEFINITION The process that occurs after viral attachment by which a virion, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
2010-12-12 Added DEFINITION The process in which a virion enters a host cell, including virion attachment and penetration.
2010-12-12 Deleted DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.
2008-05-13 Added DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.
2008-05-12 Deleted DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.
2007-08-09 Added SYNONYM viral entry into host cell
2007-08-09 Deleted SYNONYM viral entry into host cell
2005-12-10 Added SYNONYM viral entry into host cell
2003-03-26 Added DEFINITION The process by which a virion enters a host cell, including virion attachment and penetration.

Relationships

Timestamp Action Category Detail
2013-12-04 Deleted RELATION is a GO:0016032 (viral process)
2013-09-27 Added RELATION part of GO:0019058 (viral life cycle)
2013-07-12 Added RELATION is a GO:0016032 (viral process)
2013-07-12 Deleted RELATION is a GO:0019048 (modulation by virus of host morphology or physiology)
2012-09-16 Deleted RELATION part of GO:0019059 (initiation of viral infection)
2012-08-24 Deleted RELATION is a GO:0022415 (viral reproductive process)
2012-03-29 Added RELATION is a GO:0022415 (viral reproductive process)
2012-03-29 Added RELATION is a GO:0019048 (modulation by virus of host morphology or physiology)
2008-04-01 Updated RELATION is a GO:0030260 (entry into host cell)
2008-04-01 Updated RELATION part of GO:0019059 (initiation of viral infection)

Cross-references

Timestamp Action Category Detail
2012-03-29 Added XREF VZ:936

Other

Timestamp Action Category Detail
2014-03-07 Added SLIM goslim_virus
2012-03-29 Added SECONDARY GO:0019063 (virion penetration into host cell)
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