spacer

GO:0046654 tetrahydrofolate biosynthetic process

Term Information

ID GO:0046654
Name tetrahydrofolate biosynthetic process
Ontology Biological Process
Definition The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
GONUTS GO:0046654 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact tetrahydrofolate biosynthesis
exact tetrahydrofolate formation
exact tetrahydrofolate synthesis
exact tetrahydrofolate anabolism

Cross-Ontology Relations

Relation Other Ontology ID Term
has_output CHEBI CHEBI:26907 tetrahydrofolic acid

Cross-references

Database ID
InterPro IPR001474
InterPro IPR016261
InterPro IPR018234
MetaCyc FOLSYN-PWY

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046654:
Relationship To GO:0046654 Child Term Child Term Name
Is a GO:0009257 10-formyltetrahydrofolate biosynthetic process

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0046654. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0046654 based on the entire annotation set Co-occurrence statistics for GO:0046654 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-11-25 Deleted RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2010-10-11 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2010-10-11 Added DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
2009-08-21 Added RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2009-05-21 Deleted XREF MetaCyc:PWY-3742
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2008-04-01 Updated RELATION is a GO:0046653 (tetrahydrofolate metabolic process)
2008-04-01 Updated RELATION is a GO:0009396 (folic acid-containing compound biosynthetic process)
2007-08-09 Added SYNONYM tetrahydrofolate anabolism
2007-08-09 Added SYNONYM tetrahydrofolate biosynthesis
2007-08-09 Added SYNONYM tetrahydrofolate formation
2007-08-09 Added SYNONYM tetrahydrofolate synthesis
2007-08-09 Deleted SYNONYM tetrahydrofolate biosynthesis
2007-08-09 Deleted SYNONYM tetrahydrofolate anabolism
2007-08-09 Deleted SYNONYM tetrahydrofolate formation
2007-08-09 Deleted SYNONYM tetrahydrofolate synthesis
2007-07-19 Added XREF MetaCyc:PWY-3742
2007-07-19 Added XREF MetaCyc:FOLSYN-PWY
2007-01-15 Updated TERM tetrahydrofolate biosynthetic process
2007-01-15 Added SYNONYM tetrahydrofolate biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2005-08-10 Added SYNONYM tetrahydrofolate anabolism
2005-08-10 Added SYNONYM tetrahydrofolate formation
2005-08-10 Added SYNONYM tetrahydrofolate synthesis
2002-11-27 Added DEFINITION The formation from simpler components of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2002-10-30 Added TERM tetrahydrofolate biosynthesis

Term

Timestamp Action Category Detail
2007-01-15 Updated TERM tetrahydrofolate biosynthetic process
2002-10-30 Added TERM tetrahydrofolate biosynthesis

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2010-10-11 Added DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2007-08-09 Added SYNONYM tetrahydrofolate anabolism
2007-08-09 Added SYNONYM tetrahydrofolate biosynthesis
2007-08-09 Added SYNONYM tetrahydrofolate formation
2007-08-09 Added SYNONYM tetrahydrofolate synthesis
2007-08-09 Deleted SYNONYM tetrahydrofolate biosynthesis
2007-08-09 Deleted SYNONYM tetrahydrofolate anabolism
2007-08-09 Deleted SYNONYM tetrahydrofolate formation
2007-08-09 Deleted SYNONYM tetrahydrofolate synthesis
2007-01-15 Added SYNONYM tetrahydrofolate biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.
2005-08-10 Added SYNONYM tetrahydrofolate anabolism
2005-08-10 Added SYNONYM tetrahydrofolate formation
2005-08-10 Added SYNONYM tetrahydrofolate synthesis
2002-11-27 Added DEFINITION The formation from simpler components of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.

Relationships

Timestamp Action Category Detail
2010-11-25 Deleted RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2009-08-21 Added RELATION is a GO:0042559 (pteridine-containing compound biosynthetic process)
2008-04-01 Updated RELATION is a GO:0046653 (tetrahydrofolate metabolic process)
2008-04-01 Updated RELATION is a GO:0009396 (folic acid-containing compound biosynthetic process)

Cross-references

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:PWY-3742
2007-07-19 Added XREF MetaCyc:PWY-3742
2007-07-19 Added XREF MetaCyc:FOLSYN-PWY
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
13ms