spacer

GO:0046639 negative regulation of alpha-beta T cell differentiation

Term Information

ID GO:0046639
Name negative regulation of alpha-beta T cell differentiation
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
Comment Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
GONUTS GO:0046639 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative regulation of alpha-beta T-lymphocyte differentiation
exact negative regulation of alpha-beta T-cell differentiation
exact negative regulation of alpha-beta T lymphocyte differentiation
narrow inhibition of alpha-beta T cell differentiation
exact downregulation of alpha-beta T cell differentiation
exact down-regulation of alpha-beta T cell differentiation
exact down regulation of alpha-beta T cell differentiation
related negative regulation of alpha-beta T cell development

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046639:
Relationship To GO:0046639 Child Term Child Term Name
Is a GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation
Is a GO:0043377 negative regulation of CD8-positive, alpha-beta T cell differentiation
Is a GO:0051137 negative regulation of NK T cell differentiation

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0046639. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0046639 based on the entire annotation set Co-occurrence statistics for GO:0046639 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-15 Added SYNONYM negative regulation of alpha-beta T cell development
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2008-04-01 Added RELATION negatively regulates GO:0046632 (alpha-beta T cell differentiation)
2008-04-01 Updated RELATION is a GO:0046637 (regulation of alpha-beta T cell differentiation)
2008-04-01 Updated RELATION is a GO:0046636 (negative regulation of alpha-beta T cell activation)
2008-04-01 Updated RELATION is a GO:0045581 (negative regulation of T cell differentiation)
2007-08-09 Added SYNONYM down regulation of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM down-regulation of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM downregulation of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM inhibition of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM negative regulation of alpha-beta T lymphocyte differentiation
2007-08-09 Added SYNONYM negative regulation of alpha-beta T-cell differentiation
2007-08-09 Added SYNONYM negative regulation of alpha-beta T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM down regulation of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM down-regulation of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM downregulation of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM inhibition of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM negative regulation of alpha-beta T lymphocyte differentiation
2007-08-09 Deleted SYNONYM negative regulation of alpha-beta T-cell differentiation
2007-08-09 Deleted SYNONYM negative regulation of alpha-beta T-lymphocyte differentiation
2007-02-23 Added SYNONYM down regulation of alpha-beta T cell differentiation
2007-02-23 Added SYNONYM down-regulation of alpha-beta T cell differentiation
2007-02-23 Added SYNONYM downregulation of alpha-beta T cell differentiation
2007-02-23 Added SYNONYM inhibition of alpha-beta T cell differentiation
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of alpha-beta T cell differentiation.
2005-06-02 Added SYNONYM negative regulation of alpha-beta T lymphocyte differentiation
2005-06-02 Added SYNONYM negative regulation of alpha-beta T-cell differentiation
2005-06-02 Added SYNONYM negative regulation of alpha-beta T-lymphocyte differentiation
2005-06-02 Updated TERM negative regulation of alpha-beta T cell differentiation
2005-05-26 Updated DEFINITION Any process that stops, prevents or reduces the rate of alpha-beta T cell differentiation.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of alpha-beta T-cell differentiation.
2002-10-30 Added TERM negative regulation of alpha-beta T-cell differentiation

Term

Timestamp Action Category Detail
2005-06-02 Updated TERM negative regulation of alpha-beta T cell differentiation
2002-10-30 Added TERM negative regulation of alpha-beta T-cell differentiation

Definition/synonyms

Timestamp Action Category Detail
2010-10-15 Added SYNONYM negative regulation of alpha-beta T cell development
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2007-08-09 Added SYNONYM down regulation of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM down-regulation of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM downregulation of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM inhibition of alpha-beta T cell differentiation
2007-08-09 Added SYNONYM negative regulation of alpha-beta T lymphocyte differentiation
2007-08-09 Added SYNONYM negative regulation of alpha-beta T-cell differentiation
2007-08-09 Added SYNONYM negative regulation of alpha-beta T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM down regulation of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM down-regulation of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM downregulation of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM inhibition of alpha-beta T cell differentiation
2007-08-09 Deleted SYNONYM negative regulation of alpha-beta T lymphocyte differentiation
2007-08-09 Deleted SYNONYM negative regulation of alpha-beta T-cell differentiation
2007-08-09 Deleted SYNONYM negative regulation of alpha-beta T-lymphocyte differentiation
2007-02-23 Added SYNONYM down regulation of alpha-beta T cell differentiation
2007-02-23 Added SYNONYM down-regulation of alpha-beta T cell differentiation
2007-02-23 Added SYNONYM downregulation of alpha-beta T cell differentiation
2007-02-23 Added SYNONYM inhibition of alpha-beta T cell differentiation
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of alpha-beta T cell differentiation.
2005-06-02 Added SYNONYM negative regulation of alpha-beta T lymphocyte differentiation
2005-06-02 Added SYNONYM negative regulation of alpha-beta T-cell differentiation
2005-06-02 Added SYNONYM negative regulation of alpha-beta T-lymphocyte differentiation
2005-05-26 Updated DEFINITION Any process that stops, prevents or reduces the rate of alpha-beta T cell differentiation.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of alpha-beta T-cell differentiation.

Relationships

Timestamp Action Category Detail
2008-04-01 Added RELATION negatively regulates GO:0046632 (alpha-beta T cell differentiation)
2008-04-01 Updated RELATION is a GO:0046637 (regulation of alpha-beta T cell differentiation)
2008-04-01 Updated RELATION is a GO:0046636 (negative regulation of alpha-beta T cell activation)
2008-04-01 Updated RELATION is a GO:0045581 (negative regulation of T cell differentiation)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
13ms