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GO:0046632 alpha-beta T cell differentiation

Term Information

ID GO:0046632
Name alpha-beta T cell differentiation
Ontology Biological Process
Definition The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
Comment Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
GONUTS GO:0046632 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact alpha-beta T-cell differentiation
exact alpha-beta T lymphocyte differentiation
exact alpha-beta T-lymphocyte differentiation
related alpha-beta T cell development

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000299 GO:0032501 multicellular organismal process only_in_taxon 2759 Eukaryota
GOTAX:0000537 GO:0032501 multicellular organismal process never_in_taxon 4932 Saccharomyces cerevisiae
GOTAX:0000538 GO:0032501 multicellular organismal process never_in_taxon 4896 Schizosaccharomyces pombe
More information on taxon constraints in GO is available here

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000789 alpha-beta T cell

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046632:
Relationship To GO:0046632 Child Term Child Term Name
Part of GO:0043366 beta selection
Is a GO:0002293 alpha-beta T cell differentiation involved in immune response
Is a GO:0002299 alpha-beta intraepithelial T cell differentiation
Part of GO:0002363 alpha-beta T cell lineage commitment
Regulates GO:0046637 regulation of alpha-beta T cell differentiation
Positively regulates GO:0046638 positive regulation of alpha-beta T cell differentiation
Negatively regulates GO:0046639 negative regulation of alpha-beta T cell differentiation
Is a GO:0043367 CD4-positive, alpha-beta T cell differentiation
Is a GO:0043374 CD8-positive, alpha-beta T cell differentiation
Is a GO:0001865 NK T cell differentiation

Protein Annotation

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Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0046632. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0046632 based on the entire annotation set Co-occurrence statistics for GO:0046632 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-12-17 Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2010-12-17 Added DEFINITION The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2010-10-15 Added SYNONYM alpha-beta T cell development
2010-10-14 Added DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2010-10-14 Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-05-13 Added DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-05-12 Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-04-01 Updated RELATION is a GO:0046631 (alpha-beta T cell activation)
2008-04-01 Updated RELATION is a GO:0030217 (T cell differentiation)
2008-03-11 Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2007-08-09 Added SYNONYM alpha-beta T lymphocyte differentiation
2007-08-09 Added SYNONYM alpha-beta T-cell differentiation
2007-08-09 Added SYNONYM alpha-beta T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM alpha-beta T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM alpha-beta T lymphocyte differentiation
2007-08-09 Deleted SYNONYM alpha-beta T-cell differentiation
2005-06-02 Added SYNONYM alpha-beta T lymphocyte differentiation
2005-06-02 Added SYNONYM alpha-beta T-cell differentiation
2005-06-02 Added SYNONYM alpha-beta T-lymphocyte differentiation
2005-06-02 Updated DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T cell.
2005-06-02 Updated TERM alpha-beta T cell differentiation
2005-05-26 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T cell.
2005-01-21 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T-cell.
2002-11-27 Added DEFINITION The process by which a hemopoietic stem cell acquires characteristics of an alpha-beta T-cell.
2002-10-30 Added TERM alpha-beta T-cell differentiation

Term

Timestamp Action Category Detail
2005-06-02 Updated TERM alpha-beta T cell differentiation
2002-10-30 Added TERM alpha-beta T-cell differentiation

Definition/synonyms

Timestamp Action Category Detail
2010-12-17 Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2010-12-17 Added DEFINITION The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2010-10-15 Added SYNONYM alpha-beta T cell development
2010-10-14 Added DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2010-10-14 Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-05-13 Added DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-05-12 Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-03-11 Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2007-08-09 Added SYNONYM alpha-beta T lymphocyte differentiation
2007-08-09 Added SYNONYM alpha-beta T-cell differentiation
2007-08-09 Added SYNONYM alpha-beta T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM alpha-beta T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM alpha-beta T lymphocyte differentiation
2007-08-09 Deleted SYNONYM alpha-beta T-cell differentiation
2005-06-02 Added SYNONYM alpha-beta T lymphocyte differentiation
2005-06-02 Added SYNONYM alpha-beta T-cell differentiation
2005-06-02 Added SYNONYM alpha-beta T-lymphocyte differentiation
2005-06-02 Updated DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T cell.
2005-05-26 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T cell.
2005-01-21 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T-cell.
2002-11-27 Added DEFINITION The process by which a hemopoietic stem cell acquires characteristics of an alpha-beta T-cell.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0046631 (alpha-beta T cell activation)
2008-04-01 Updated RELATION is a GO:0030217 (T cell differentiation)
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