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EBIDatabasesQuickGO

GO:0045861 negative regulation of proteolysis

Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.

Term Information

ID GO:0045861
Name negative regulation of proteolysis
Ontology Biological Process
Definition Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Comment

Synonyms

Type Synonym
exact negative regulation of peptidolysis
narrow inhibition of proteolysis
exact downregulation of proteolysis
exact down-regulation of proteolysis
exact down regulation of proteolysis

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GTerm?id=termID&format=format

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0065007 biological regulation
GO:0050789 regulation of biological process
GO:0043170 macromolecule metabolic process
GO:0009056 catabolic process
GO:0044238 primary metabolic process
GO:0044237 cellular metabolic process
GO:0048519 negative regulation of biological process
GO:0043283 biopolymer metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0009057 macromolecule catabolic process
GO:0044260 cellular macromolecule metabolic process
GO:0019538 protein metabolic process
GO:0048523 negative regulation of cellular process
GO:0009894 regulation of catabolic process
GO:0080090 regulation of primary metabolic process
GO:0060255 regulation of macromolecule metabolic process
GO:0009892 negative regulation of metabolic process
GO:0043285 biopolymer catabolic process
GO:0034960 cellular biopolymer metabolic process
GO:0031323 regulation of cellular metabolic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0009895 negative regulation of catabolic process
GO:0030163 protein catabolic process
GO:0044267 cellular protein metabolic process
GO:0006508 proteolysis
GO:0051246 regulation of protein metabolic process
GO:0031324 negative regulation of cellular metabolic process
GO:0051248 negative regulation of protein metabolic process
GO:0042176 regulation of protein catabolic process
GO:0032268 regulation of cellular protein metabolic process
GO:0030162 regulation of proteolysis
GO:0042177 negative regulation of protein catabolic process
GO:0032269 negative regulation of cellular protein metabolic process
GO:0045861 negative regulation of proteolysis

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0002629 negative regulation of proteolysis associated with antigen processing and presentation
I GO:0051045 negative regulation of membrane protein ectodomain proteolysis
I GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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15ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-24-04-03-40
Terminal
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