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GO:0045861 negative regulation of proteolysis

Term Information

ID GO:0045861
Name negative regulation of proteolysis
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GONUTS GO:0045861 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact downregulation of proteolysis
exact down-regulation of proteolysis
exact down regulation of proteolysis
narrow inhibition of proteolysis
exact negative regulation of peptidolysis

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045861:
Relationship To GO:0045861 Child Term Child Term Name
Is a GO:0002629 negative regulation of proteolysis associated with antigen processing and presentation
Is a GO:0051045 negative regulation of membrane protein ectodomain proteolysis
Is a GO:1901799 negative regulation of proteasomal protein catabolic process

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045861. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045861 based on the entire annotation set Co-occurrence statistics for GO:0045861 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-03-07 Added RELATION is a GO:0010955 (negative regulation of protein processing)
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2010-02-13 Deleted RELATION is a GO:0042177 (negative regulation of protein catabolic process)
2009-05-21 Added RELATION is a GO:0042177 (negative regulation of protein catabolic process)
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2008-04-01 Updated RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2008-04-01 Updated RELATION is a GO:0030162 (regulation of proteolysis)
2008-04-01 Added RELATION negatively regulates GO:0006508 (proteolysis)
2007-08-09 Added SYNONYM down regulation of proteolysis
2007-08-09 Added SYNONYM down-regulation of proteolysis
2007-08-09 Added SYNONYM downregulation of proteolysis
2007-08-09 Added SYNONYM inhibition of proteolysis
2007-08-09 Added SYNONYM negative regulation of peptidolysis
2007-08-09 Deleted SYNONYM down regulation of proteolysis
2007-08-09 Deleted SYNONYM down-regulation of proteolysis
2007-08-09 Deleted SYNONYM downregulation of proteolysis
2007-08-09 Deleted SYNONYM inhibition of proteolysis
2007-08-09 Deleted SYNONYM negative regulation of peptidolysis
2007-02-23 Added SYNONYM down regulation of proteolysis
2007-02-23 Added SYNONYM down-regulation of proteolysis
2007-02-23 Added SYNONYM downregulation of proteolysis
2007-02-23 Added SYNONYM inhibition of proteolysis
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the hydrolysis of a peptide bond or bonds within a protein.
2005-09-19 Updated TERM negative regulation of proteolysis
2005-09-19 Added SYNONYM negative regulation of peptidolysis
2005-09-17 Updated DEFINITION Any process that stops, prevents or reduces the rate of the hydrolysis of a peptide bond or bonds within a protein.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of proteolysis and peptidolysis.
2002-08-20 Added TERM negative regulation of proteolysis and peptidolysis

Term

Timestamp Action Category Detail
2005-09-19 Updated TERM negative regulation of proteolysis
2002-08-20 Added TERM negative regulation of proteolysis and peptidolysis

Definition/synonyms

Timestamp Action Category Detail
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2007-08-09 Added SYNONYM down regulation of proteolysis
2007-08-09 Added SYNONYM down-regulation of proteolysis
2007-08-09 Added SYNONYM downregulation of proteolysis
2007-08-09 Added SYNONYM inhibition of proteolysis
2007-08-09 Added SYNONYM negative regulation of peptidolysis
2007-08-09 Deleted SYNONYM down regulation of proteolysis
2007-08-09 Deleted SYNONYM down-regulation of proteolysis
2007-08-09 Deleted SYNONYM downregulation of proteolysis
2007-08-09 Deleted SYNONYM inhibition of proteolysis
2007-08-09 Deleted SYNONYM negative regulation of peptidolysis
2007-02-23 Added SYNONYM down regulation of proteolysis
2007-02-23 Added SYNONYM down-regulation of proteolysis
2007-02-23 Added SYNONYM downregulation of proteolysis
2007-02-23 Added SYNONYM inhibition of proteolysis
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the hydrolysis of a peptide bond or bonds within a protein.
2005-09-19 Added SYNONYM negative regulation of peptidolysis
2005-09-17 Updated DEFINITION Any process that stops, prevents or reduces the rate of the hydrolysis of a peptide bond or bonds within a protein.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of proteolysis and peptidolysis.

Relationships

Timestamp Action Category Detail
2014-03-07 Added RELATION is a GO:0010955 (negative regulation of protein processing)
2010-02-13 Deleted RELATION is a GO:0042177 (negative regulation of protein catabolic process)
2009-05-21 Added RELATION is a GO:0042177 (negative regulation of protein catabolic process)
2008-04-01 Updated RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2008-04-01 Updated RELATION is a GO:0030162 (regulation of proteolysis)
2008-04-01 Added RELATION negatively regulates GO:0006508 (proteolysis)
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