spacer

GO:0045786 negative regulation of cell cycle

Term Information

ID GO:0045786
Name negative regulation of cell cycle
Ontology Biological Process
Definition Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
GONUTS GO:0045786 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative regulation of progression through cell cycle
exact down regulation of progression through cell cycle
exact down-regulation of progression through cell cycle
exact negative regulation of cell cycle progression
exact downregulation of progression through cell cycle
narrow inhibition of progression through cell cycle

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
cell cycleLink

Cross-references

Database ID
InterPro IPR028319
InterPro IPR029697

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045786:
Relationship To GO:0045786 Child Term Child Term Name
Is a GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
Is a GO:0045839 negative regulation of mitosis
Is a GO:0051447 negative regulation of meiotic cell cycle
Is a GO:0045930 negative regulation of mitotic cell cycle
Is a GO:0010948 negative regulation of cell cycle process
Is a GO:0007050 cell cycle arrest
Is a GO:2000002 negative regulation of DNA damage checkpoint
Is a GO:0070317 negative regulation of G0 to G1 transition
Is a GO:0044072 negative regulation by symbiont of host cell cycle

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045786. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045786 based on the entire annotation set Co-occurrence statistics for GO:0045786 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
2008-04-01 Updated RELATION is a GO:0048523 (negative regulation of cellular process)
2008-04-01 Updated RELATION is a GO:0051726 (regulation of cell cycle)
2008-04-01 Added RELATION negatively regulates GO:0007049 (cell cycle)
2007-12-27 Updated DEFINITION Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
2007-12-10 Added SYNONYM negative regulation of progression through cell cycle
2007-12-10 Updated TERM negative regulation of cell cycle
2007-08-09 Added SYNONYM downregulation of progression through cell cycle
2007-08-09 Added SYNONYM inhibition of progression through cell cycle
2007-08-09 Added SYNONYM negative regulation of cell cycle progression
2007-08-09 Added SYNONYM down regulation of progression through cell cycle
2007-08-09 Added SYNONYM down-regulation of progression through cell cycle
2007-08-09 Deleted SYNONYM down regulation of progression through cell cycle
2007-08-09 Deleted SYNONYM down-regulation of progression through cell cycle
2007-08-09 Deleted SYNONYM downregulation of progression through cell cycle
2007-08-09 Deleted SYNONYM inhibition of progression through cell cycle
2007-08-09 Deleted SYNONYM negative regulation of cell cycle progression
2007-02-23 Added SYNONYM down regulation of progression through cell cycle
2007-02-23 Added SYNONYM down-regulation of progression through cell cycle
2007-02-23 Added SYNONYM downregulation of progression through cell cycle
2007-02-23 Added SYNONYM inhibition of progression through cell cycle
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of progression through the cell cycle.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the cell cycle.
2005-07-22 Updated TERM negative regulation of progression through cell cycle
2005-07-22 Added SYNONYM negative regulation of cell cycle progression
2005-06-30 Updated DEFINITION Any process that stops, prevents or reduces the rate of progression through the cell cycle.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of cell cycle activity.
2002-08-20 Added TERM negative regulation of cell cycle

Term

Timestamp Action Category Detail
2007-12-10 Updated TERM negative regulation of cell cycle
2005-07-22 Updated TERM negative regulation of progression through cell cycle
2002-08-20 Added TERM negative regulation of cell cycle

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
2007-12-27 Updated DEFINITION Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
2007-12-10 Added SYNONYM negative regulation of progression through cell cycle
2007-08-09 Added SYNONYM downregulation of progression through cell cycle
2007-08-09 Added SYNONYM inhibition of progression through cell cycle
2007-08-09 Added SYNONYM negative regulation of cell cycle progression
2007-08-09 Added SYNONYM down regulation of progression through cell cycle
2007-08-09 Added SYNONYM down-regulation of progression through cell cycle
2007-08-09 Deleted SYNONYM down regulation of progression through cell cycle
2007-08-09 Deleted SYNONYM down-regulation of progression through cell cycle
2007-08-09 Deleted SYNONYM downregulation of progression through cell cycle
2007-08-09 Deleted SYNONYM inhibition of progression through cell cycle
2007-08-09 Deleted SYNONYM negative regulation of cell cycle progression
2007-02-23 Added SYNONYM down regulation of progression through cell cycle
2007-02-23 Added SYNONYM down-regulation of progression through cell cycle
2007-02-23 Added SYNONYM downregulation of progression through cell cycle
2007-02-23 Added SYNONYM inhibition of progression through cell cycle
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of progression through the cell cycle.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the cell cycle.
2005-07-22 Added SYNONYM negative regulation of cell cycle progression
2005-06-30 Updated DEFINITION Any process that stops, prevents or reduces the rate of progression through the cell cycle.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of cell cycle activity.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0048523 (negative regulation of cellular process)
2008-04-01 Updated RELATION is a GO:0051726 (regulation of cell cycle)
2008-04-01 Added RELATION negatively regulates GO:0007049 (cell cycle)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
22ms