spacer

GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway

Term Information

ID GO:0045744
Name negative regulation of G-protein coupled receptor protein signaling pathway
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
GONUTS GO:0045744 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative regulation of GPCR protein signaling pathway
exact negative regulation of GPCR protein signalling pathway
exact negative regulation of G-protein-coupled receptor protein signalling pathway
exact negative regulation of G-protein-coupled receptor protein signaling pathway
exact negative regulation of G-protein coupled receptor protein signalling pathway
exact negative regulation of G protein coupled receptor protein signalling pathway
exact negative regulation of G protein coupled receptor protein signaling pathway
narrow inhibition of G-protein coupled receptor protein signaling pathway
exact downregulation of G-protein coupled receptor protein signaling pathway
exact down-regulation of G-protein coupled receptor protein signaling pathway
exact down regulation of G-protein coupled receptor protein signaling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0016299 regulator of G-protein signaling activity CONSIDER GO:0045744

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045744:
Relationship To GO:0045744 Child Term Child Term Name
Is a GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway
Is a GO:0071878 negative regulation of adrenergic receptor signaling pathway
Is a GO:0060160 negative regulation of dopamine receptor signaling pathway
Is a GO:0060169 negative regulation of adenosine receptor signaling pathway
Is a GO:0090029 negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
Is a GO:2000126 negative regulation of octopamine or tyramine signaling pathway
Is a GO:0075089 negative regulation by host of symbiont G-protein coupled receptor protein signal transduction
Is a GO:0075120 negative regulation by symbiont of host G-protein coupled receptor protein signal transduction
Is a GO:0075158 negative regulation of G-protein coupled receptor protein signaling pathway in response to host
Is a GO:0070495 negative regulation of thrombin receptor signaling pathway
Is a GO:0038032 termination of G-protein coupled receptor signaling pathway
Is a GO:2000475 negative regulation of opioid receptor signaling pathway
Is a GO:1990172 G-protein coupled receptor catabolic process
Is a GO:1900737 negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045744. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045744 based on the entire annotation set Co-occurrence statistics for GO:0045744 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-01-16 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2011-01-16 Deleted RELATION is a GO:0035467 (negative regulation of signaling pathway)
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2010-04-21 Added RELATION is a GO:0035467 (negative regulation of signaling pathway)
2010-04-21 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2008-04-01 Updated RELATION is a GO:0008277 (regulation of G-protein coupled receptor protein signaling pathway)
2008-04-01 Added RELATION negatively regulates GO:0007186 (G-protein coupled receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0009968 (negative regulation of signal transduction)
2007-08-09 Added SYNONYM negative regulation of G protein coupled receptor protein signalling pathway
2007-08-09 Added SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2007-08-09 Added SYNONYM negative regulation of G-protein-coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM negative regulation of G-protein-coupled receptor protein signalling pathway
2007-08-09 Added SYNONYM negative regulation of GPCR protein signaling pathway
2007-08-09 Added SYNONYM negative regulation of GPCR protein signalling pathway
2007-08-09 Added SYNONYM down regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM down-regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM downregulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM inhibition of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM negative regulation of G protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM down-regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM downregulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM inhibition of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM down regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of G protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of G protein coupled receptor protein signalling pathway
2007-08-09 Deleted SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2007-08-09 Deleted SYNONYM negative regulation of G-protein-coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of G-protein-coupled receptor protein signalling pathway
2007-08-09 Deleted SYNONYM negative regulation of GPCR protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of GPCR protein signalling pathway
2007-02-23 Added SYNONYM down regulation of G-protein coupled receptor protein signaling pathway
2007-02-23 Added SYNONYM down-regulation of G-protein coupled receptor protein signaling pathway
2007-02-23 Added SYNONYM downregulation of G-protein coupled receptor protein signaling pathway
2007-02-23 Added SYNONYM inhibition of G-protein coupled receptor protein signaling pathway
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of G-protein coupled receptor protein signaling pathway activity.
2005-06-27 Added SYNONYM negative regulation of G protein coupled receptor protein signaling pathway
2005-06-27 Added SYNONYM negative regulation of G protein coupled receptor protein signalling pathway
2005-06-27 Added SYNONYM negative regulation of G-protein-coupled receptor protein signaling pathway
2005-06-27 Added SYNONYM negative regulation of G-protein-coupled receptor protein signalling pathway
2005-06-27 Added SYNONYM negative regulation of GPCR protein signaling pathway
2005-06-27 Added SYNONYM negative regulation of GPCR protein signalling pathway
2004-04-19 Added SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2004-04-16 Deleted SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2003-11-13 Added SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of G-protein coupled receptor protein signaling pathway activity.
2002-08-20 Added TERM negative regulation of G-protein coupled receptor protein signaling pathway

Term

Timestamp Action Category Detail
2002-08-20 Added TERM negative regulation of G-protein coupled receptor protein signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2007-08-09 Added SYNONYM negative regulation of G protein coupled receptor protein signalling pathway
2007-08-09 Added SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2007-08-09 Added SYNONYM negative regulation of G-protein-coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM negative regulation of G-protein-coupled receptor protein signalling pathway
2007-08-09 Added SYNONYM negative regulation of GPCR protein signaling pathway
2007-08-09 Added SYNONYM negative regulation of GPCR protein signalling pathway
2007-08-09 Added SYNONYM down regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM down-regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM downregulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM inhibition of G-protein coupled receptor protein signaling pathway
2007-08-09 Added SYNONYM negative regulation of G protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM down-regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM downregulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM inhibition of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM down regulation of G-protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of G protein coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of G protein coupled receptor protein signalling pathway
2007-08-09 Deleted SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2007-08-09 Deleted SYNONYM negative regulation of G-protein-coupled receptor protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of G-protein-coupled receptor protein signalling pathway
2007-08-09 Deleted SYNONYM negative regulation of GPCR protein signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of GPCR protein signalling pathway
2007-02-23 Added SYNONYM down regulation of G-protein coupled receptor protein signaling pathway
2007-02-23 Added SYNONYM down-regulation of G-protein coupled receptor protein signaling pathway
2007-02-23 Added SYNONYM downregulation of G-protein coupled receptor protein signaling pathway
2007-02-23 Added SYNONYM inhibition of G-protein coupled receptor protein signaling pathway
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of G-protein coupled receptor protein signaling pathway activity.
2005-06-27 Added SYNONYM negative regulation of G protein coupled receptor protein signaling pathway
2005-06-27 Added SYNONYM negative regulation of G protein coupled receptor protein signalling pathway
2005-06-27 Added SYNONYM negative regulation of G-protein-coupled receptor protein signaling pathway
2005-06-27 Added SYNONYM negative regulation of G-protein-coupled receptor protein signalling pathway
2005-06-27 Added SYNONYM negative regulation of GPCR protein signaling pathway
2005-06-27 Added SYNONYM negative regulation of GPCR protein signalling pathway
2004-04-19 Added SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2004-04-16 Deleted SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2003-11-13 Added SYNONYM negative regulation of G-protein coupled receptor protein signalling pathway
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of G-protein coupled receptor protein signaling pathway activity.

Relationships

Timestamp Action Category Detail
2011-01-16 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2011-01-16 Deleted RELATION is a GO:0035467 (negative regulation of signaling pathway)
2010-04-21 Added RELATION is a GO:0035467 (negative regulation of signaling pathway)
2010-04-21 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2008-04-01 Updated RELATION is a GO:0008277 (regulation of G-protein coupled receptor protein signaling pathway)
2008-04-01 Added RELATION negatively regulates GO:0007186 (G-protein coupled receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0009968 (negative regulation of signal transduction)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
16ms