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GO:0045548 phenylalanine ammonia-lyase activity

Term Information

ID GO:0045548
Name phenylalanine ammonia-lyase activity
Ontology Molecular Function
Definition Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.
GONUTS GO:0045548 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact L-phenylalanine ammonia-lyase activity
exact phenylalanine ammonium-lyase activity
exact phenylalanine deaminase activity
exact phe ammonia-lyase activity
broad PAL activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 4.3.1.24
EC 4.3.1.25
RHEA 21387

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045548:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045548. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045548 based on the entire annotation set Co-occurrence statistics for GO:0045548 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-03-01 Added DEFINITION Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.
2012-03-01 Deleted DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.
2012-03-01 Added SYNONYM PAL activity
2012-03-01 Added SYNONYM phe ammonia-lyase activity
2012-03-01 Deleted SYNONYM L-tyrosine ammonia-lyase activity
2012-03-01 Deleted SYNONYM L-phenylalanine ammonia-lyase (trans-cinnamate-forming)
2012-03-01 Deleted SYNONYM tyrase activity
2012-03-01 Deleted SYNONYM PAL
2012-03-01 Added XREF RHEA:21387
2012-03-01 Added XREF EC:4.3.1.25
2012-03-01 Added XREF EC:4.3.1.24
2012-03-01 Deleted XREF MetaCyc:PHENYLALANINE-AMMONIA-LYASE-RXN
2012-03-01 Deleted XREF EC:4.3.1.5
2012-03-01 Deleted SYNONYM tyrosine ammonia-lyase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.
2008-04-01 Updated RELATION is a GO:0016841 (ammonia-lyase activity)
2007-11-08 Added SYNONYM L-phenylalanine ammonia-lyase (trans-cinnamate-forming)
2007-11-08 Added SYNONYM L-phenylalanine ammonia-lyase activity
2007-11-08 Added SYNONYM L-tyrosine ammonia-lyase activity
2007-11-08 Added SYNONYM PAL
2007-11-08 Added SYNONYM phenylalanine ammonium-lyase activity
2007-11-08 Added SYNONYM phenylalanine deaminase activity
2007-11-08 Added SYNONYM tyrase activity
2007-11-08 Added SYNONYM tyrosine ammonia-lyase activity
2003-10-27 Added XREF MetaCyc:PHENYLALANINE-AMMONIA-LYASE-RXN
2003-03-19 Updated TERM phenylalanine ammonia-lyase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.
2002-08-09 Added XREF EC:4.3.1.5
2002-08-09 Added TERM phenylalanine ammonia-lyase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM phenylalanine ammonia-lyase activity
2002-08-09 Added TERM phenylalanine ammonia-lyase

Definition/synonyms

Timestamp Action Category Detail
2012-03-01 Added DEFINITION Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.
2012-03-01 Deleted DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.
2012-03-01 Added SYNONYM PAL activity
2012-03-01 Added SYNONYM phe ammonia-lyase activity
2012-03-01 Deleted SYNONYM L-tyrosine ammonia-lyase activity
2012-03-01 Deleted SYNONYM L-phenylalanine ammonia-lyase (trans-cinnamate-forming)
2012-03-01 Deleted SYNONYM tyrase activity
2012-03-01 Deleted SYNONYM PAL
2012-03-01 Deleted SYNONYM tyrosine ammonia-lyase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.
2007-11-08 Added SYNONYM L-phenylalanine ammonia-lyase (trans-cinnamate-forming)
2007-11-08 Added SYNONYM L-phenylalanine ammonia-lyase activity
2007-11-08 Added SYNONYM L-tyrosine ammonia-lyase activity
2007-11-08 Added SYNONYM PAL
2007-11-08 Added SYNONYM phenylalanine ammonium-lyase activity
2007-11-08 Added SYNONYM phenylalanine deaminase activity
2007-11-08 Added SYNONYM tyrase activity
2007-11-08 Added SYNONYM tyrosine ammonia-lyase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016841 (ammonia-lyase activity)

Cross-references

Timestamp Action Category Detail
2012-03-01 Added XREF RHEA:21387
2012-03-01 Added XREF EC:4.3.1.25
2012-03-01 Added XREF EC:4.3.1.24
2012-03-01 Deleted XREF MetaCyc:PHENYLALANINE-AMMONIA-LYASE-RXN
2012-03-01 Deleted XREF EC:4.3.1.5
2003-10-27 Added XREF MetaCyc:PHENYLALANINE-AMMONIA-LYASE-RXN
2002-08-09 Added XREF EC:4.3.1.5
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