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GO:0045248 cytosolic oxoglutarate dehydrogenase complex

Term Information

ID GO:0045248
Name cytosolic oxoglutarate dehydrogenase complex
Ontology Cellular Component
Definition A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
PMID:10848975
Comment See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
GONUTS GO:0045248 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000368 GO:0045248 cytosolic oxoglutarate dehydrogenase complex only_in_taxon 2, 2157 Prokaryota
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045248:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045248. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045248 based on the entire annotation set Co-occurrence statistics for GO:0045248 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-12-10 Added RELATION is a GO:0044445 (cytosolic part)
2009-12-10 Deleted RELATION is a GO:0044444 (cytoplasmic part)
2009-08-31 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2008-05-13 Added DEFINITION A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
2008-05-12 Deleted DEFINITION A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0045252 (oxoglutarate dehydrogenase complex)
2007-08-09 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2007-08-09 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2007-02-16 Updated DEFINITION A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
2007-02-12 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2007-02-12 Updated TERM cytosolic oxoglutarate dehydrogenase complex
2007-01-18 Updated TERM oxoglutarate dehydrogenase complex (sensu Bacteria)
2007-01-15 Updated TERM oxoglutarate dehydrogenase complex (sensu the Bacteria research community)
2005-02-02 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-07-22 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the taxon Eubacteria (Bacteria, ncbi_taxonomy_id:2).
2004-02-24 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). As in, but not restricted to, the taxon Eubacteria (Bacteria, ncbi_taxonomy_id:2).
2003-10-23 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). Found in bacteria.
2002-11-27 Added DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide within the mitochondrial matrix (GO:0005759). Found in bacteria.
2002-05-10 Added TERM oxoglutarate dehydrogenase complex (sensu Bacteria)

Term

Timestamp Action Category Detail
2007-02-12 Updated TERM cytosolic oxoglutarate dehydrogenase complex
2007-01-18 Updated TERM oxoglutarate dehydrogenase complex (sensu Bacteria)
2007-01-15 Updated TERM oxoglutarate dehydrogenase complex (sensu the Bacteria research community)
2002-05-10 Added TERM oxoglutarate dehydrogenase complex (sensu Bacteria)

Definition/synonyms

Timestamp Action Category Detail
2009-08-31 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2008-05-13 Added DEFINITION A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
2008-05-12 Deleted DEFINITION A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
2007-08-09 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2007-08-09 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2007-02-16 Updated DEFINITION A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
2007-02-12 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Bacteria)
2005-02-02 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-07-22 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the taxon Eubacteria (Bacteria, ncbi_taxonomy_id:2).
2004-02-24 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). As in, but not restricted to, the taxon Eubacteria (Bacteria, ncbi_taxonomy_id:2).
2003-10-23 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). Found in bacteria.
2002-11-27 Added DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide within the mitochondrial matrix (GO:0005759). Found in bacteria.

Relationships

Timestamp Action Category Detail
2009-12-10 Added RELATION is a GO:0044445 (cytosolic part)
2009-12-10 Deleted RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0045252 (oxoglutarate dehydrogenase complex)
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