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GO:0045202 synapse

Term Information

ID GO:0045202
Name synapse
Ontology Cellular Component
Definition The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
GONUTS GO:0045202 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow mixed synapse
related electrotonic synapse
exact synaptic junction

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000365 GO:0045202 synapse only_in_taxon 33208 Metazoa
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462

Cross-references

Database ID
InterPro IPR001237
InterPro IPR008899
InterPro IPR018293
InterPro IPR030024
InterPro IPR030025
NIF_Subcellular sao914572699
UniProtKB-KW Synapse
UniProtKB-SubCell Synapse
Wikipedia Chemical_synapse

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045202:
Relationship To GO:0045202 Child Term Child Term Name
Is a GO:0032279 asymmetric synapse
Is a GO:0032280 symmetric synapse
Is a GO:0031594 neuromuscular junction
Part of GO:0044456 synapse part
Is a GO:0060076 excitatory synapse
Is a GO:0060077 inhibitory synapse
Is a GO:0097470 ribbon synapse
Is a GO:0097471 mossy fiber rosette

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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ID Mapping

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045202. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045202 based on the entire annotation set Co-occurrence statistics for GO:0045202 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2013-02-23 Deleted SYNONYM electrotonic synapse
2013-02-23 Added SYNONYM electrotonic synapse
2013-02-22 Added SYNONYM mixed synapse
2013-02-22 Added SYNONYM electrotonic synapse
2010-02-04 Added XREF NIF_Subcellular:sao914572699
2009-02-25 Added XREF Wikipedia:Chemical_synapse
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2008-05-12 Deleted DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2008-04-01 Updated RELATION is a GO:0005575 (cellular_component)
2007-08-09 Added SYNONYM synaptic junction
2007-08-09 Deleted SYNONYM synaptic junction
2004-04-19 Added SYNONYM synaptic junction
2004-04-16 Deleted SYNONYM synaptic junction
2004-01-10 Added SYNONYM synaptic junction
2004-01-10 Deleted SYNONYM synapse
2004-01-10 Updated TERM synapse
2003-04-29 Updated DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2003-04-24 Updated DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the post-synaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the post-synaptic membrane.
2002-11-27 Added DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the pre-synaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the pre-synaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the post-synaptic membrane. In response to the arrival of nerve impulses, the pre-synaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the post-synaptic membrane.
2002-05-02 Added TERM synaptic junction
2002-05-02 Added SYNONYM synapse

Term

Timestamp Action Category Detail
2004-01-10 Updated TERM synapse
2002-05-02 Added TERM synaptic junction

Definition/synonyms

Timestamp Action Category Detail
2013-02-23 Deleted SYNONYM electrotonic synapse
2013-02-23 Added SYNONYM electrotonic synapse
2013-02-22 Added SYNONYM mixed synapse
2013-02-22 Added SYNONYM electrotonic synapse
2008-05-13 Added DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2008-05-12 Deleted DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2007-08-09 Added SYNONYM synaptic junction
2007-08-09 Deleted SYNONYM synaptic junction
2004-04-19 Added SYNONYM synaptic junction
2004-04-16 Deleted SYNONYM synaptic junction
2004-01-10 Added SYNONYM synaptic junction
2004-01-10 Deleted SYNONYM synapse
2003-04-29 Updated DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2003-04-24 Updated DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the post-synaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the post-synaptic membrane.
2002-11-27 Added DEFINITION The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the pre-synaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the pre-synaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the post-synaptic membrane. In response to the arrival of nerve impulses, the pre-synaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the post-synaptic membrane.
2002-05-02 Added SYNONYM synapse

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005575 (cellular_component)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao914572699
2009-02-25 Added XREF Wikipedia:Chemical_synapse

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2008-06-09 Added SLIM goslim_pir
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