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GO:0045174 glutathione dehydrogenase (ascorbate) activity

Term Information

ID GO:0045174
Name glutathione dehydrogenase (ascorbate) activity
Ontology Molecular Function
Definition Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.
GONUTS GO:0045174 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact dehydroascorbic acid reductase activity
exact dehydroascorbic reductase activity
exact glutathione:dehydroascorbate oxidoreductase activity
exact glutathione:dehydroascorbic acid oxidoreductase activity
exact dehydroascorbate reductase activity
related GDOR
exact DHA reductase activity
exact glutathione dehydroascorbate reductase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.8.5.1
KEGG R01108
MetaCyc 1.8.5.1-RXN
RHEA 24427

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045174:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045174. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045174 based on the entire annotation set Co-occurrence statistics for GO:0045174 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2010-10-11 Added DEFINITION Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.
2010-10-11 Added XREF KEGG:R01108
2010-10-11 Added XREF RHEA:24427
2008-06-30 Deleted RELATION is a GO:0009055 (electron carrier activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2008-04-01 Updated RELATION is a GO:0009055 (electron carrier activity)
2008-04-01 Updated RELATION is a GO:0015038 (glutathione disulfide oxidoreductase activity)
2008-04-01 Updated RELATION is a GO:0016209 (antioxidant activity)
2008-04-01 Updated RELATION is a GO:0016672 (oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor)
2007-11-08 Deleted SYNONYM dehydroascorbate reductase
2007-11-08 Added SYNONYM DHA reductase activity
2007-11-08 Added SYNONYM GDOR
2007-11-08 Added SYNONYM dehydroascorbate reductase activity
2007-11-08 Added SYNONYM dehydroascorbic acid reductase activity
2007-11-08 Added SYNONYM dehydroascorbic reductase activity
2007-11-08 Added SYNONYM glutathione dehydroascorbate reductase activity
2007-11-08 Added SYNONYM glutathione:dehydroascorbate oxidoreductase activity
2007-11-08 Added SYNONYM glutathione:dehydroascorbic acid oxidoreductase activity
2007-08-09 Added SYNONYM dehydroascorbate reductase
2007-08-09 Deleted SYNONYM dehydroascorbate reductase
2004-04-19 Added SYNONYM dehydroascorbate reductase
2004-04-16 Deleted SYNONYM dehydroascorbate reductase
2003-10-27 Added SYNONYM dehydroascorbate reductase
2003-10-27 Added XREF MetaCyc:1.8.5.1-RXN
2003-08-18 Deleted SYNONYM dehydroascorbate reductase
2003-03-26 Updated DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2003-03-19 Updated TERM glutathione dehydrogenase (ascorbate) activity
2003-03-19 Deleted SYNONYM glutathione dehydrogenase (ascorbate)
2002-12-19 Updated TERM glutathione dehydrogenase (ascorbate)
2002-12-19 Added SYNONYM dehydroascorbate reductase
2002-11-27 Added DEFINITION Catalysis of the glutathione-dependent reduction of dehydroascorbate, oxidizing glutathione in the process.
2002-04-30 Added XREF EC:1.8.5.1
2002-04-30 Added TERM dehydroascorbate reductase
2002-04-30 Added SYNONYM glutathione dehydrogenase (ascorbate)

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM glutathione dehydrogenase (ascorbate) activity
2002-12-19 Updated TERM glutathione dehydrogenase (ascorbate)
2002-04-30 Added TERM dehydroascorbate reductase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2010-10-11 Added DEFINITION Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2007-11-08 Deleted SYNONYM dehydroascorbate reductase
2007-11-08 Added SYNONYM DHA reductase activity
2007-11-08 Added SYNONYM GDOR
2007-11-08 Added SYNONYM dehydroascorbate reductase activity
2007-11-08 Added SYNONYM dehydroascorbic acid reductase activity
2007-11-08 Added SYNONYM dehydroascorbic reductase activity
2007-11-08 Added SYNONYM glutathione dehydroascorbate reductase activity
2007-11-08 Added SYNONYM glutathione:dehydroascorbate oxidoreductase activity
2007-11-08 Added SYNONYM glutathione:dehydroascorbic acid oxidoreductase activity
2007-08-09 Added SYNONYM dehydroascorbate reductase
2007-08-09 Deleted SYNONYM dehydroascorbate reductase
2004-04-19 Added SYNONYM dehydroascorbate reductase
2004-04-16 Deleted SYNONYM dehydroascorbate reductase
2003-10-27 Added SYNONYM dehydroascorbate reductase
2003-08-18 Deleted SYNONYM dehydroascorbate reductase
2003-03-26 Updated DEFINITION Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2003-03-19 Deleted SYNONYM glutathione dehydrogenase (ascorbate)
2002-12-19 Added SYNONYM dehydroascorbate reductase
2002-11-27 Added DEFINITION Catalysis of the glutathione-dependent reduction of dehydroascorbate, oxidizing glutathione in the process.
2002-04-30 Added SYNONYM glutathione dehydrogenase (ascorbate)

Relationships

Timestamp Action Category Detail
2008-06-30 Deleted RELATION is a GO:0009055 (electron carrier activity)
2008-04-01 Updated RELATION is a GO:0009055 (electron carrier activity)
2008-04-01 Updated RELATION is a GO:0015038 (glutathione disulfide oxidoreductase activity)
2008-04-01 Updated RELATION is a GO:0016209 (antioxidant activity)
2008-04-01 Updated RELATION is a GO:0016672 (oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF KEGG:R01108
2010-10-11 Added XREF RHEA:24427
2003-10-27 Added XREF MetaCyc:1.8.5.1-RXN
2002-04-30 Added XREF EC:1.8.5.1
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