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GO:0045121 membrane raft

Term Information

ID GO:0045121
Name membrane raft
Ontology Cellular Component
Definition Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
PMID:16645198 PMID:20044567
GONUTS GO:0045121 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact lipid raft
related glycolipid-enriched membrane domain
related GEM domain

Cross-references

Database ID
InterPro IPR028209
InterPro IPR032748
InterPro IPR033240
UniProtKB-SubCell Membrane raft
Wikipedia Lipid_raft

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045121:
Relationship To GO:0045121 Child Term Child Term Name
Part of GO:0071986 Ragulator complex
Is a GO:0044853 plasma membrane raft

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045121. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045121 based on the entire annotation set Co-occurrence statistics for GO:0045121 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-10-24 Deleted RELATION is a GO:0098589 (membrane region)
2015-10-24 Added RELATION is a GO:0098857 (membrane microdomain)
2014-08-09 Deleted RELATION is a GO:0044425 (membrane part)
2014-08-09 Added RELATION is a GO:0098589 (membrane region)
2009-02-25 Added XREF Wikipedia:Lipid_raft
2008-05-13 Added DEFINITION Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2008-05-12 Deleted DEFINITION Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2008-04-27 Updated DEFINITION Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2008-04-01 Updated RELATION is a GO:0044425 (membrane part)
2008-03-02 Added SYNONYM lipid raft
2008-03-02 Updated TERM membrane raft
2007-10-04 Added SYNONYM GEM domain
2007-10-04 Added SYNONYM glycolipid-enriched membrane domain
2007-04-20 Updated DEFINITION Specialized membrane domains composed mainly of cholesterol and sphingolipids, and relatively poor in polyunsaturated lipids such as glycerophospholipids. The formation of these membrane domains is promoted by the presence of cholesterol in the lipid bilayer: the rigid hexagonal rings of cholesterol can pack tightly against the saturated hydrocarbon chains of some membrane lipids, allowing these lipids to assemble into cohesive units floating in the mass of loosely packed polyunsaturated plasma membrane components.
2002-11-27 Added DEFINITION Specialized membrane domains composed mainly of cholesterol and sphingolipids, and are relatively poor in polyunsaturated lipids such as glycerophospholipids. The formation of these membrane domains is promoted by the presence of cholesterol in the lipid bilayer: the rigid hexagonal rings of cholesterol can pack tightly against the saturated hydrocarbon chains of some membrane lipids, allowing these lipids to assemble into cohesive units floating in the mass of loosely packed polyunsaturated plasma membrane components.
2002-04-18 Added TERM lipid raft

Term

Timestamp Action Category Detail
2008-03-02 Updated TERM membrane raft
2002-04-18 Added TERM lipid raft

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2008-05-12 Deleted DEFINITION Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2008-04-27 Updated DEFINITION Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2008-03-02 Added SYNONYM lipid raft
2007-10-04 Added SYNONYM GEM domain
2007-10-04 Added SYNONYM glycolipid-enriched membrane domain
2007-04-20 Updated DEFINITION Specialized membrane domains composed mainly of cholesterol and sphingolipids, and relatively poor in polyunsaturated lipids such as glycerophospholipids. The formation of these membrane domains is promoted by the presence of cholesterol in the lipid bilayer: the rigid hexagonal rings of cholesterol can pack tightly against the saturated hydrocarbon chains of some membrane lipids, allowing these lipids to assemble into cohesive units floating in the mass of loosely packed polyunsaturated plasma membrane components.
2002-11-27 Added DEFINITION Specialized membrane domains composed mainly of cholesterol and sphingolipids, and are relatively poor in polyunsaturated lipids such as glycerophospholipids. The formation of these membrane domains is promoted by the presence of cholesterol in the lipid bilayer: the rigid hexagonal rings of cholesterol can pack tightly against the saturated hydrocarbon chains of some membrane lipids, allowing these lipids to assemble into cohesive units floating in the mass of loosely packed polyunsaturated plasma membrane components.

Relationships

Timestamp Action Category Detail
2015-10-24 Deleted RELATION is a GO:0098589 (membrane region)
2015-10-24 Added RELATION is a GO:0098857 (membrane microdomain)
2014-08-09 Deleted RELATION is a GO:0044425 (membrane part)
2014-08-09 Added RELATION is a GO:0098589 (membrane region)
2008-04-01 Updated RELATION is a GO:0044425 (membrane part)

Cross-references

Timestamp Action Category Detail
2009-02-25 Added XREF Wikipedia:Lipid_raft
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