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GO:0045095 keratin filament

A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.

Term Information

ID GO:0045095
Name keratin filament
Ontology Cellular Component
Definition A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.
Comment
Secondary IDs

GONUTS Wiki Page

Synonyms

Type Synonym
related acidic keratin
related basic/neutral keratin

Cross-references associated with this term:

Database ID
INTERPRO IPR007659
INTERPRO IPR003054
INTERPRO IPR002494

This term can be used instead of these obsolete terms:

GO:0045097 basic/neutral keratin (replaced_by GO:0045095)
GO:0045096 acidic keratin (replaced_by GO:0045095)

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Ancestor Table

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GO:0005575 cellular_component
GO:0043226 organelle
GO:0032991 macromolecular complex
GO:0005623 cell
GO:0043234 protein complex
GO:0044422 organelle part
GO:0043228 non-membrane-bounded organelle
GO:0044464 cell part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0044446 intracellular organelle part
GO:0043232 intracellular non-membrane-bounded organelle
GO:0005856 cytoskeleton
GO:0045111 intermediate filament cytoskeleton
GO:0044430 cytoskeletal part
GO:0005882 intermediate filament
GO:0045095 keratin filament

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Term has no children

Protein Annotation

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9606 Human
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40674 Mammalia
3398 Magnoliophyta (flowering plants)
2759 Eukaryota
1117 Cyanobacteria
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GO Terms:
GO:0045095
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Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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Hostnametomcat-7.ebi.ac.uk
Uptime11:21 5/2/2010
Data version2010-02-10-03-49-32
Terminal
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