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GO:0045047 protein targeting to ER

Term Information

ID GO:0045047
Name protein targeting to ER
Ontology Biological Process
Definition The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
GONUTS GO:0045047 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact protein targeting to endoplasmic reticulum
exact protein-endoplasmic reticulum targeting
exact protein-ER targeting

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045047:
Relationship To GO:0045047 Child Term Child Term Name
Is a GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Is a GO:0006620 posttranslational protein targeting to membrane

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045047. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045047 based on the entire annotation set Co-occurrence statistics for GO:0045047 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-09-18 Added RELATION is a GO:1902580 (single-organism cellular localization)
2014-09-18 Added RELATION is a GO:0070972 (protein localization to endoplasmic reticulum)
2013-02-02 Added RELATION is a GO:0016482 (cytoplasmic transport)
2011-02-15 Added RELATION is a GO:0072599 (establishment of protein localization to endoplasmic reticulum)
2011-02-15 Deleted RELATION part of GO:0070972 (protein localization to endoplasmic reticulum)
2010-02-24 Deleted RELATION part of GO:0071539 (protein localization to centrosome)
2010-01-14 Added RELATION part of GO:0071539 (protein localization to centrosome)
2009-10-07 Added RELATION part of GO:0070972 (protein localization to endoplasmic reticulum)
2008-05-13 Added DEFINITION The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2008-05-12 Deleted DEFINITION The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2008-04-30 Deleted RELATION part of GO:0045045 (secretory pathway)
2008-04-01 Updated RELATION part of GO:0045045 (secretory pathway)
2008-04-01 Updated RELATION is a GO:0006605 (protein targeting)
2007-08-09 Added SYNONYM protein targeting to endoplasmic reticulum
2007-08-09 Added SYNONYM protein-ER targeting
2007-08-09 Added SYNONYM protein-endoplasmic reticulum targeting
2007-08-09 Deleted SYNONYM protein targeting to endoplasmic reticulum
2007-08-09 Deleted SYNONYM protein-ER targeting
2007-08-09 Deleted SYNONYM protein-endoplasmic reticulum targeting
2005-09-11 Updated TERM protein targeting to ER
2005-09-11 Added SYNONYM protein-ER targeting
2005-09-11 Deleted SYNONYM protein targeting to ER
2004-11-05 Added SYNONYM protein targeting to endoplasmic reticulum
2004-11-05 Added SYNONYM protein-endoplasmic reticulum targeting
2004-11-05 Added SYNONYM protein targeting to ER
2004-03-24 Updated DEFINITION The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2003-04-29 Updated DEFINITION The process of directing proteins towards the ER using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2002-11-27 Added DEFINITION The process of directing proteins towards the ER using signals contained within the protein. A 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2002-04-10 Added TERM protein-ER targeting

Term

Timestamp Action Category Detail
2005-09-11 Updated TERM protein targeting to ER
2002-04-10 Added TERM protein-ER targeting

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2008-05-12 Deleted DEFINITION The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2007-08-09 Added SYNONYM protein targeting to endoplasmic reticulum
2007-08-09 Added SYNONYM protein-ER targeting
2007-08-09 Added SYNONYM protein-endoplasmic reticulum targeting
2007-08-09 Deleted SYNONYM protein targeting to endoplasmic reticulum
2007-08-09 Deleted SYNONYM protein-ER targeting
2007-08-09 Deleted SYNONYM protein-endoplasmic reticulum targeting
2005-09-11 Added SYNONYM protein-ER targeting
2005-09-11 Deleted SYNONYM protein targeting to ER
2004-11-05 Added SYNONYM protein targeting to endoplasmic reticulum
2004-11-05 Added SYNONYM protein-endoplasmic reticulum targeting
2004-11-05 Added SYNONYM protein targeting to ER
2004-03-24 Updated DEFINITION The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2003-04-29 Updated DEFINITION The process of directing proteins towards the ER using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
2002-11-27 Added DEFINITION The process of directing proteins towards the ER using signals contained within the protein. A 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.

Relationships

Timestamp Action Category Detail
2014-09-18 Added RELATION is a GO:1902580 (single-organism cellular localization)
2014-09-18 Added RELATION is a GO:0070972 (protein localization to endoplasmic reticulum)
2013-02-02 Added RELATION is a GO:0016482 (cytoplasmic transport)
2011-02-15 Added RELATION is a GO:0072599 (establishment of protein localization to endoplasmic reticulum)
2011-02-15 Deleted RELATION part of GO:0070972 (protein localization to endoplasmic reticulum)
2010-02-24 Deleted RELATION part of GO:0071539 (protein localization to centrosome)
2010-01-14 Added RELATION part of GO:0071539 (protein localization to centrosome)
2009-10-07 Added RELATION part of GO:0070972 (protein localization to endoplasmic reticulum)
2008-04-30 Deleted RELATION part of GO:0045045 (secretory pathway)
2008-04-01 Updated RELATION part of GO:0045045 (secretory pathway)
2008-04-01 Updated RELATION is a GO:0006605 (protein targeting)
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