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GO:0045040 protein import into mitochondrial outer membrane

The import of proteins into the outer membrane of the mitochondrion. Outer membrane proteins have a short matrix-targeting sequence followed by a long stretch of hydrophobic amino acids at the N-terminus. The hydrophobic sequence functions as a stop-transfer sequence that both prevents transfer of the protein into the matrix and anchors it as an integral protein in the outer membrane.

Term Information

ID GO:0045040
Name protein import into mitochondrial outer membrane
Ontology Biological Process
Definition The import of proteins into the outer membrane of the mitochondrion. Outer membrane proteins have a short matrix-targeting sequence followed by a long stretch of hydrophobic amino acids at the N-terminus. The hydrophobic sequence functions as a stop-transfer sequence that both prevents transfer of the protein into the matrix and anchors it as an integral protein in the outer membrane.
Comment

Synonyms

Type Synonym
exact mitochondrial outer membrane protein import
exact protein transport into mitochondrial outer membrane

Cross-references associated with this term:

Database ID
INTERPRO IPR010547

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Ancestor Table

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GO:0008150 biological_process
GO:0051179 localization
GO:0009987 cellular process
GO:0016043 cellular component organization
GO:0051234 establishment of localization
GO:0033036 macromolecule localization
GO:0016044 membrane organization
GO:0006810 transport
GO:0051641 cellular localization
GO:0006996 organelle organization
GO:0008104 protein localization
GO:0007005 mitochondrion organization
GO:0070727 cellular macromolecule localization
GO:0051649 establishment of localization in cell
GO:0045184 establishment of protein localization
GO:0007006 mitochondrial membrane organization
GO:0046907 intracellular transport
GO:0007008 outer mitochondrial membrane organization
GO:0034613 cellular protein localization
GO:0015031 protein transport
GO:0017038 protein import
GO:0006839 mitochondrial transport
GO:0033365 protein localization in organelle
GO:0070585 protein localization in mitochondrion
GO:0006886 intracellular protein transport
GO:0006605 protein targeting
GO:0006612 protein targeting to membrane
GO:0006626 protein targeting to mitochondrion
GO:0045040 protein import into mitochondrial outer membrane

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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