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GO:0045012 obsolete MHC class II receptor activity

This term is obsolete.
This term was made obsolete because it was defined ambiguously, and has therefore been used incorrectly in annotations. To update annotations of gene products that act as receptors for MHC class II protein complexes, use the molecular function term 'MHC class II receptor activity ; GO:0032395'; to update annotations of gene products which are components of MHC class II protein complexes, use the cellular component term 'MHC class II protein complex ; GO:0042613'.

Term Information

ID GO:0045012
Name obsolete MHC class II receptor activity
Ontology Molecular Function
Definition OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
Comment This term was made obsolete because it was defined ambiguously, and has therefore been used incorrectly in annotations. To update annotations of gene products that act as receptors for MHC class II protein complexes, use the molecular function term 'MHC class II receptor activity ; GO:0032395'; to update annotations of gene products which are components of MHC class II protein complexes, use the cellular component term 'MHC class II protein complex ; GO:0042613'.
GONUTS GO:0045012 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact MHC class II receptor activity
related class II major histocompatibility complex antigen
exact major histocompatibility complex class II receptor

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Consider GO:0032395 Molecular Function MHC class II receptor activity
Consider GO:0042613 Cellular Component MHC class II protein complex

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045012:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045012. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045012 based on the entire annotation set Co-occurrence statistics for GO:0045012 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-06-18 Updated TERM obsolete MHC class II receptor activity
2015-06-18 Added SYNONYM MHC class II receptor activity
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2010-06-08 Updated TERM MHC class II receptor activity
2008-06-03 Added OBSOLETION consider GO:0032395 (MHC class II receptor activity)
2008-06-03 Added OBSOLETION consider GO:0042613 (MHC class II protein complex)
2008-05-13 Added DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2008-05-12 Deleted DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2008-04-01 Updated RELATION is a GO:0008369 (obsolete molecular function)
2007-08-09 Added SYNONYM class II major histocompatibility complex antigen
2007-08-09 Added SYNONYM major histocompatibility complex class II receptor
2007-08-09 Deleted SYNONYM class II major histocompatibility complex antigen
2007-08-09 Deleted SYNONYM major histocompatibility complex class II receptor
2006-11-21 Updated DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2005-08-10 Added SYNONYM class II major histocompatibility complex antigen
2004-04-19 Added SYNONYM major histocompatibility complex class II receptor
2004-04-16 Deleted SYNONYM major histocompatibility complex class II receptor
2003-03-19 Updated TERM MHC class II receptor activity
2003-03-04 Added SYNONYM major histocompatibility complex class II receptor
2002-11-27 Added DEFINITION A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2002-03-17 Added TERM MHC class II receptor

Term

Timestamp Action Category Detail
2015-06-18 Updated TERM obsolete MHC class II receptor activity
2010-06-08 Updated TERM MHC class II receptor activity
2003-03-19 Updated TERM MHC class II receptor activity
2002-03-17 Added TERM MHC class II receptor

Obsoletions

Timestamp Action Category Detail
2008-06-03 Added OBSOLETION consider GO:0032395 (MHC class II receptor activity)
2008-06-03 Added OBSOLETION consider GO:0042613 (MHC class II protein complex)

Definition/synonyms

Timestamp Action Category Detail
2015-06-18 Added SYNONYM MHC class II receptor activity
2008-05-13 Added DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2008-05-12 Deleted DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2007-08-09 Added SYNONYM class II major histocompatibility complex antigen
2007-08-09 Added SYNONYM major histocompatibility complex class II receptor
2007-08-09 Deleted SYNONYM class II major histocompatibility complex antigen
2007-08-09 Deleted SYNONYM major histocompatibility complex class II receptor
2006-11-21 Updated DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2005-08-10 Added SYNONYM class II major histocompatibility complex antigen
2004-04-19 Added SYNONYM major histocompatibility complex class II receptor
2004-04-16 Deleted SYNONYM major histocompatibility complex class II receptor
2003-03-04 Added SYNONYM major histocompatibility complex class II receptor
2002-11-27 Added DEFINITION A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.

Relationships

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-04-01 Updated RELATION is a GO:0008369 (obsolete molecular function)
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