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GO:0043687 post-translational protein modification

The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.

Term Information

ID GO:0043687
Name post-translational protein modification
Ontology Biological Process
Definition The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.
Comment

Synonyms

Type Synonym
exact PTM
exact post-translational amino acid modification
exact post-translational modification
exact posttranslational modification
exact posttranslational protein modification
exact posttranslational amino acid modification

Cross-references associated with this term:

Database ID
Wikipedia Posttranslational_modification
INTERPRO IPR000608

Web service: term information

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0043170 macromolecule metabolic process
GO:0044238 primary metabolic process
GO:0044237 cellular metabolic process
GO:0043283 biopolymer metabolic process
GO:0043412 biopolymer modification
GO:0044260 cellular macromolecule metabolic process
GO:0019538 protein metabolic process
GO:0034960 cellular biopolymer metabolic process
GO:0044267 cellular protein metabolic process
GO:0006464 protein modification process
GO:0043687 post-translational protein modification

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0016570 histone modification
I GO:0016598 protein arginylation
I GO:0016926 protein desumoylation
I GO:0017006 protein-tetrapyrrole linkage
I GO:0017013 protein amino acid flavinylation
I GO:0017014 protein amino acid nitrosylation
I GO:0018065 protein-cofactor linkage
I GO:0018079 protein amino acid halogenation
I GO:0018094 protein polyglycylation
I GO:0018126 protein amino acid hydroxylation
I GO:0018143 nucleic acid-protein covalent cross-linking
I GO:0018298 protein-chromophore linkage
I GO:0018307 enzyme active site formation
I GO:0018322 protein amino acid tyrosinylation
I GO:0018335 protein amino acid succinylation
I GO:0006467 protein thiol-disulfide exchange
I GO:0018350 protein amino acid esterification
I GO:0018410 peptide or protein carboxyl-terminal blocking
I GO:0018411 protein amino acid glucuronidation
I GO:0009305 protein amino acid biotinylation
I GO:0006468 protein amino acid phosphorylation
I GO:0018149 peptide cross-linking
I GO:0018158 protein amino acid oxidation
I GO:0006470 protein amino acid dephosphorylation
I GO:0006471 protein amino acid ADP-ribosylation
I GO:0030047 actin modification
I GO:0030923 metal incorporation into metallo-oxygen cluster
I GO:0031162 sulfur incorporation into metallo-sulfur cluster
I GO:0001318 formation of oxidatively modified proteins during replicative cell aging
I GO:0006476 protein amino acid deacetylation
I GO:0006477 protein amino acid sulfation
I GO:0008213 protein amino acid alkylation
I GO:0008214 protein amino acid dealkylation
I GO:0000413 protein peptidyl-prolyl isomerization
I GO:0000338 protein deneddylation
I GO:0018175 protein amino acid nucleotidylation
I GO:0018180 protein amino acid desulfurization
I GO:0018184 protein amino acid polyamination
I GO:0018214 protein amino acid carboxylation
I GO:0018215 protein amino acid phosphopantetheinylation
I GO:0018249 protein amino acid dehydration
I GO:0018282 metal incorporation into metallo-sulfur cluster
I GO:0016255 attachment of GPI anchor to protein
I GO:0046944 protein amino acid carbamoylation
I GO:0051697 protein delipidation
I GO:0051725 protein amino acid de-ADP-ribosylation
I GO:0016925 protein sumoylation
I GO:0019951 Smt3-protein conjugation
I GO:0032447 protein urmylation
I GO:0045116 protein neddylation
I GO:0016567 protein ubiquitination
I GO:0070084 protein initiator methionine removal
I GO:0032020 ISG15-protein conjugation
I GO:0016579 protein deubiquitination
I GO:0042040 metal incorporation into metallo-molybdopterin complex
I GO:0070490 protein pupylation

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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