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GO:0043490 malate-aspartate shuttle

Term Information

ID GO:0043490
Name malate-aspartate shuttle
Ontology Biological Process
Definition The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
GONUTS GO:0043490 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact malate:aspartate shuttle
exact malate/aspartate shuttle
exact malate aspartate shuttle

Cross-references

Database ID
Wikipedia Malate-aspartate_shuttle

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043490:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0043490. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0043490 based on the entire annotation set Co-occurrence statistics for GO:0043490 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-03-29 Added XREF Wikipedia:Malate-aspartate_shuttle
2008-05-13 Added DEFINITION The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
2008-05-12 Deleted DEFINITION The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
2008-04-01 Updated RELATION part of GO:0022904 (respiratory electron transport chain)
2008-04-01 Updated RELATION is a GO:0006839 (mitochondrial transport)
2007-08-09 Added SYNONYM malate aspartate shuttle
2007-08-09 Added SYNONYM malate/aspartate shuttle
2007-08-09 Added SYNONYM malate:aspartate shuttle
2007-08-09 Deleted SYNONYM malate aspartate shuttle
2007-08-09 Deleted SYNONYM malate/aspartate shuttle
2007-08-09 Deleted SYNONYM malate:aspartate shuttle
2005-09-04 Added SYNONYM malate:aspartate shuttle
2005-09-04 Added SYNONYM malate/aspartate shuttle
2005-09-04 Added SYNONYM malate aspartate shuttle
2005-09-04 Added DEFINITION The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
2005-09-04 Added TERM malate-aspartate shuttle

Term

Timestamp Action Category Detail
2005-09-04 Added TERM malate-aspartate shuttle

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
2008-05-12 Deleted DEFINITION The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
2007-08-09 Added SYNONYM malate aspartate shuttle
2007-08-09 Added SYNONYM malate/aspartate shuttle
2007-08-09 Added SYNONYM malate:aspartate shuttle
2007-08-09 Deleted SYNONYM malate aspartate shuttle
2007-08-09 Deleted SYNONYM malate/aspartate shuttle
2007-08-09 Deleted SYNONYM malate:aspartate shuttle
2005-09-04 Added SYNONYM malate:aspartate shuttle
2005-09-04 Added SYNONYM malate/aspartate shuttle
2005-09-04 Added SYNONYM malate aspartate shuttle
2005-09-04 Added DEFINITION The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION part of GO:0022904 (respiratory electron transport chain)
2008-04-01 Updated RELATION is a GO:0006839 (mitochondrial transport)

Cross-references

Timestamp Action Category Detail
2009-03-29 Added XREF Wikipedia:Malate-aspartate_shuttle
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